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October 2024 - January 1908

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July 2021, Vol 181, No. 7, Pages 894-1024

Viewpoint

Dealing With Death as an Outcome in Supportive Care Clinical Trials

Scott D. Halpern, MD, PhD; Jennifer S. Temel, MD; Katherine R. Courtright, MD, MS
Abstract Full Text
JAMA Intern Med. 2021;181(7):895-896. doi:10.1001/jamainternmed.2021.1816

This Viewpoint seeks to provide guidance to investigators of palliative and supportive care clinical trials to improve end-of-life care for patient and caregiver.

Integrating New Effectiveness Data Into US Food and Drug Administration鈥揂pproved Drug Labeling

Bishal Gyawali, MD, PhD; Jonathan J. Darrow, SJD, JD, MBA; Aaron S. Kesselheim, MD, JD, MPH
Abstract Full Text
JAMA Intern Med. 2021;181(7):897-898. doi:10.1001/jamainternmed.2021.1994

This Viewpoint assesses US Food and Drug Administration policies regarding drug label changes.

A Clinical Approach to Preventing Death on the Streets

Katherine A. Koh, MD, MSc; Jill S. Roncarati, ScD, MPH, PA-C; James J. O鈥機onnell, MD
Abstract Full Text
has audio
JAMA Intern Med. 2021;181(7):899-901. doi:10.1001/jamainternmed.2021.2402

This Viewpoint offers a novel framework to empower clinicians to assess a person in need on the street and prevent avoidable death.

  • Podcast: A Clinical Approach to Preventing Death on the Streets
Perspective

Screening for Traumatic Experiences in Health Care Settings: A Personal Perspective From a Trauma Survivor

Anna E. Austin, PhD
Abstract Full Text
JAMA Intern Med. 2021;181(7):902-903. doi:10.1001/jamainternmed.2021.1452

This physician perspective describes failings in the trauma disclosure system currently in place in the new patient intake process of most health care facilities.

Original Investigation

Physician Work Environment and Well-Being

Delay of Pregnancy Among Physicians vs Nonphysicians

Maria C. Cusimano, MD; Nancy N. Baxter, PhD; Rinku Sutradhar, PhD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):905-912. doi:10.1001/jamainternmed.2021.1635

This cohort study compares patterns of childbirth among physicians vs nonphysicians.

Comparison of Estimated Effectiveness of Case-Based and Population-Based Interventions on COVID-19 Containment in Taiwan

Ta-Chou Ng, BSc; Hao-Yuan Cheng, MD, MSc; Hsiao-Han Chang, PhD; et al.
Abstract Full Text
open access
JAMA Intern Med. 2021;181(7):913-921. doi:10.1001/jamainternmed.2021.1644

This comparative effectiveness research study examines case-based and population-based interventions and their association with COVID-19 control in Taiwan.

Effectiveness of a Vaping Cessation Text Message Program Among Young Adult e-Cigarette Users: A Randomized Clinical Trial

Amanda L. Graham, PhD; Michael S. Amato, PhD; Sarah Cha, MSPH; et al.
Abstract Full Text
open access
JAMA Intern Med. 2021;181(7):923-930. doi:10.1001/jamainternmed.2021.1793

This randomized clinical trial determines the effectiveness of a text message program for vaping cessation among young adults aged 18 to 24 years vs assessment-only control.

Health Care Reform

Hospital Responses to Incentives in Episode-Based Payment for Joint Surgery: A Controlled Population-Based Study

Andrew D. Wilcock, PhD; Michael L. Barnett, MD; J. Michael McWilliams, MD, PhD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):932-940. doi:10.1001/jamainternmed.2021.1897

This controlled population-based study investigates the response of hospitals to changing incentives in Medicare鈥檚 Comprehensive Care for Joint Replacement program, an episode-based payment model.

Association of Low-Value Care Exposure With Health Care Experience Ratings Among Patient Panels

Prachi Sanghavi, PhD; J. Michael McWilliams, MD, PhD; Aaron L. Schwartz, MD, PhD; et al.
Abstract Full Text
open access
JAMA Intern Med. 2021;181(7):941-948. doi:10.1001/jamainternmed.2021.1974

This quality improvement study assesses associations between rates of low-value service provision to a primary care professional patient panel and patients鈥� ratings of their health care experiences.

Factors Associated With Access to and Receipt of Liver Transplantation in Veterans With End-stage Liver Disease

Fasiha Kanwal, MD, MSHS; Ruben Hernaez, MD, PhD; Yan Liu, MS; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):949-959. doi:10.1001/jamainternmed.2021.2051

This cohort study uses data from the United Network of Organ Sharing to assess the factors associated with referral, wait-listing, and receipt of liver allografts in veterans with end-stage liver disease.

SARS-CoV-2 Transmission Risk Among National Basketball Association Players, Staff, and Vendors Exposed to Individuals With Positive Test Results After COVID-19 Recovery During the 2020 Regular and Postseason

Christina D. Mack, PhD, MSPH; John DiFiori, MD; Caroline G. Tai, PhD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):960-966. doi:10.1001/jamainternmed.2021.2114

This cohort study examines viral dynamics and transmission of infection for National Basketball Association players, staff, and vendors who had clinically recovered from SARS-CoV-2 infection but continued to have positive test results following discontinuation of isolation precautions.

Socioeconomic Inequality in Respiratory Health in the US From 1959 to 2018

Adam W. Gaffney, MD, MPH; David U. Himmelstein, MD; David C. Christiani, MD, MS, MPH; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):968-976. doi:10.1001/jamainternmed.2021.2441

This cross-sectional study examines long-term trends in socioeconomic disparities in respiratory disease prevalence, pulmonary symptoms, and pulmonary function

Invited Commentary

Screening for Traumatic Childhood Experiences in Health Care Settings

David Finkelhor, PhD; Lucy Berliner, MSW
Abstract Full Text
JAMA Intern Med. 2021;181(7):903-904. doi:10.1001/jamainternmed.2021.1442

An Inexpensive Intervention to Reduce e-Cigarette Use Among Young Adults

Anand R. Habib, MD, MPhil; Mitchell H. Katz, MD
Abstract Full Text
JAMA Intern Med. 2021;181(7):930-931. doi:10.1001/jamainternmed.2021.1791

Health Care Reform

Lung Health Disparities in Time

Emily Brigham, MD, MHS; Sarath Raju, MD, MPH
Abstract Full Text
JAMA Intern Med. 2021;181(7):976-977. doi:10.1001/jamainternmed.2021.2572
Editor's Note

Lessons From the Success of COVID-19 Control in Taiwan

Robert Steinbrook, MD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):922. doi:10.1001/jamainternmed.2021.1625

COVID-19 Lessons From the National Basketball Association Bubble鈥擟an Persistently SARS-CoV-2鈥揚ositive Individuals Transmit Infection to Others?

James W. Salazar, MD, MAS; Mitchell H. Katz, MD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):967. doi:10.1001/jamainternmed.2021.2121

Reassessment of Glycemic Goals in Older Patients With Dementia鈥擬ore Work Is Needed to Do Less

Jennifer D. Claytor, MD, MS; Richard W. Grant, MD, MPH
Abstract Full Text
JAMA Intern Med. 2021;181(7):994-995. doi:10.1001/jamainternmed.2021.1834
Teachable Moment

The Key Role of Nonpharmacologic Management of Cachexia in Persons With Advanced Illness: A Teachable Moment

Aamna Kabani, BA; Sydney M. Dy, MD, MS; Arjun Gupta, MD
Abstract Full Text
JAMA Intern Med. 2021;181(7):978-979. doi:10.1001/jamainternmed.2021.1533

This Teachable Moment considers the psychological distress that anorexia and/or cachexia leads to in caregivers and patients with advanced illness, and how clinicians can help without using pharmacologic management.

Research Letter

Less Is More

Glycemic Control and Use of High-risk Antihyperglycemic Agents Among Nursing Home Residents With Diabetes in Ontario, Canada

Iliana C. Lega, MD; Michael A. Campitelli, MSc; Jeremy Matlow, MD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):992-994. doi:10.1001/jamainternmed.2021.0022

This cohort study examines levels of glycemic control among nursing home residents with diabetes and compares rates of intensive glycemic control with high-risk antihyperglycemic agents across levels of cognitive impairment.

Health Care Policy and Law

Frequency of First Generic Drug Approvals With 鈥淪kinny Labels鈥� in the United States

Bryan S. Walsh, JD; Ameet Sarpatwari, PhD, JD; Benjamin N. Rome, MD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):995-997. doi:10.1001/jamainternmed.2021.0484

This cohort study assessed the frequency of approvals of first generic drugs with skinny labels in the US.

Incidence of 30-Day Venous Thromboembolism in Adults Tested for SARS-CoV-2 Infection in an Integrated Health Care System in Northern California

Nareg H. Roubinian, MD; Jennifer R. Dusendang, MPH; Dustin G. Mark, MD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):997-999. doi:10.1001/jamainternmed.2021.0488

This cohort study examines the 30-day incidence of outpatient and hospital-associated venous thromboembolism following SARS-CoV-2 testing among adults in a large health system.

The COVID-GRAM Tool for Patients Hospitalized With COVID-19 in Europe

Óscar Moreno-Pérez, MD, PhD; Mariano Andrés, MD, PhD; José Manuel León-Ramirez, MD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1000-1001. doi:10.1001/jamainternmed.2021.0491

This study applies a clinical risk assessment tool (COVID-GRAM) developed in China to a population of patients hospitalized with COVID-19 in Spain to evaluate the tool鈥檚 usefulness in Europe.

Incorporating HIV Screening With COVID-19 Testing in an Urban Emergency Department During the Pandemic

Kimberly A. Stanford, MD, MPH; Moira C. McNulty, MD, MS; Jessica R. Schmitt, LCSW, AM; et al.
Abstract Full Text
open access
JAMA Intern Med. 2021;181(7):1001-1003. doi:10.1001/jamainternmed.2021.0839

This cohort study reports the results of incorporating HIV screening into COVID-19 testing at the University of Chicago emergency department.

Systematic Assessment of Online Health Information for Coronary Revascularization

Irbaz Hameed, MD; N. U. Farrukh Hameed, MD, Mch; Christian T. Oakley, BS; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1003-1006. doi:10.1001/jamainternmed.2021.1051

This cross-sectional study examines the readability, accuracy, content, quality, and suitability of online health information on coronary artery bypass grafting or percutaneous coronary intervention for patients.

Hand Hygiene Compliance Rate During the COVID-19 Pandemic

Sonya Makhni, MD, MBA; Craig A. Umscheid, MD, MS; Jackie Soo, MPH, ScD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1006-1008. doi:10.1001/jamainternmed.2021.1429

This quality improvement study assesses hand hygiene compliance rates in a hospital with an automated hand hygiene monitoring system during the COVID-19 pandemic.

Association of Race/Ethnicity With Likeliness of COVID-19 Vaccine Uptake Among Health Workers and the General Population in the San Francisco Bay Area

Kevin Grumbach, MD; Timothy Judson, MD, MPH; Manisha Desai, PhD; et al.
Abstract Full Text
open access
JAMA Intern Med. 2021;181(7):1008-1011. doi:10.1001/jamainternmed.2021.1445

This cross-sectional survey study investigates COVID-19 vaccine intentions among racially and ethnically diverse samples of health workers and the general population.

Challenges in Clinical Electrocardiography

Less Is More

Dual Tachycardia in a Middle-aged Woman: Occam鈥檚 Razor vs Hickam鈥檚 Dictum

Aayush K. Singal, MD, DM; Raghav Bansal, MD, DM; Sandeep Seth, MD, DM
Abstract Full Text
JAMA Intern Med. 2021;181(7):980-982. doi:10.1001/jamainternmed.2021.1434

This case report presents the electrocardiographic findings of a woman in her 40s with obesity who presented to the emergency department with a first episode of acute-onset palpitations for 1 hour.

Isolated ST-Elevation Myocardial Infarction of the Diagonal: Time to Think Lateral

Venkatakrishnan Ramakumar, DM; Ram Manohar Talupula, MD; Satyavir Yadav, DM
Abstract Full Text
JAMA Intern Med. 2021;181(7):983-984. doi:10.1001/jamainternmed.2021.1575

This case report describes a man in his 50s presented to the emergency department with sudden-onset retrosternal chest pain. What is your diagnosis?

An Unusual Cause of Macroscopic T-Wave Alternans in a Patient With Acute Promyelocytic Leukemia

Zhen-Hua Liang, MD; Yun-Tao Zhao, MD; Yi-Chang Zhou, MD
Abstract Full Text
JAMA Intern Med. 2021;181(7):985-987. doi:10.1001/jamainternmed.2021.1631

This case study presents the electrocardiographic findings in a man in his 50s with a history of acute promyelocytic leukemia treated with arsenic trioxide who was hospitalized with recurrent loss of consciousness.

Taking Time With the RP Interval in Narrow Complex Tachycardia

John M. Cunningham, MD; Ryan Borne, MD
Abstract Full Text
JAMA Intern Med. 2021;181(7):988-989. doi:10.1001/jamainternmed.2021.1981

This case report describes the electrocardiographic findings in a man in his 80s without prior history of arrhythmia who presented with cough and shortness of breath during the COVID-19 pandemic.

Beat-to-Beat Variation in QRS Morphology Following Transcatheter Aortic Valve Replacement

Natee Sirinvaravong, MD; Datun Qi, MD; Gan-Xin Yan, MD, PhD
Abstract Full Text
JAMA Intern Med. 2021;181(7):990-991. doi:10.1001/jamainternmed.2021.1997

This case report describes beat-to-beat variation in QRS morphology occurring in a patient who has undergone transcatheter aortic valve replacement.

JAMA Internal Medicine Patient Page

I Am Concerned About Osteoporosis: What Do I Need to Know?

Katie L. Kaput, DO; Vishnu Sundaresh, MD, MS
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1024. doi:10.1001/jamainternmed.2021.1628

This Patient Page provides information regarding osteoporosis risk and treatments.

Comment & Response

Treatment of Fibromyalgia in the 21st Century

Maria J. Silveira, MD, MA, MPH; Kevin F. Boehnke, PHD; Dan Clauw, MD
Abstract Full Text
JAMA Intern Med. 2021;181(7):1011. doi:10.1001/jamainternmed.2020.9276

Treatment of Fibromyalgia in the 21st Century鈥擱eply

Rodrigo Oliveira Mascarenhas, MSc; Mateus Bastos Souza, BAppSc; Vinicius Cunha Oliveira, PhD
Abstract Full Text
JAMA Intern Med. 2021;181(7):1011-1012. doi:10.1001/jamainternmed.2020.9293

Drug-Eluting vs Bare-Metal Stents for Percutaneous Coronary Intervention

Alfredo M. Rodríguez-Granillo, MD; Carlos Fernández-Pereira, MD, PhD; Alfredo E. Rodríguez, MD, PhD
Abstract Full Text
JAMA Intern Med. 2021;181(7):1012-1013. doi:10.1001/jamainternmed.2021.0030

Drug-Eluting vs Bare-Metal Stents for Percutaneous Coronary Intervention鈥擱eply

Irbaz Hameed, MD; Mario Gaudino, MD, PhD, MSCE
Abstract Full Text
JAMA Intern Med. 2021;181(7):1013. doi:10.1001/jamainternmed.2021.0033

SARS-CoV-2 Seroprevalence Data to Guide Local Public Health Interventions

Lao-Tzu Allan-Blitz, MD; Jeffrey D. Klausner, MD, MPH
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1014. doi:10.1001/jamainternmed.2021.0074

Factors Contributing to Missing COVID-19 Cases During Contact Tracing

Shannan N. Rich, MSc; Veronica L. Richards, MPH; Emily M. Klann, MPH
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1014-1015. doi:10.1001/jamainternmed.2021.0077

Factors Contributing to Missing COVID-19 Cases During Contact Tracing鈥擱eply

Darpun D. Sachdev, MD; Stephanie E. Cohen, MD, MPH; Susan Scheer, PhD, MPH
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1015. doi:10.1001/jamainternmed.2021.0071

Narrative Ethics in Response to Unbearable Suffering鈥攖he Dutch Slippery Slope Is Nonexistent

Barend W. Florijn, MD, PhD; Ad A. Kaptein, PhD
Abstract Full Text
JAMA Intern Med. 2021;181(7):1016. doi:10.1001/jamainternmed.2021.0198

Narrative Ethics in Response to Unbearable Suffering鈥攖he Dutch Slippery Slope Is Nonexistent

Jan Bollen, LLM, MD, PhD; Walther van Mook, MD, PhD; Kris Vissers, MD, PhD
Abstract Full Text
JAMA Intern Med. 2021;181(7):1016-1017. doi:10.1001/jamainternmed.2021.0212

Health Care Policy and Law

Narrative Ethics in Response to Unbearable Suffering鈥攖he Dutch Slippery Slope Is Nonexistent鈥擱eply

Diane E. Meier, MD
Abstract Full Text
JAMA Intern Med. 2021;181(7):1017. doi:10.1001/jamainternmed.2021.0201

Tocilizumab in Treatment for Patients With COVID-19

Chengliang Yang, MD; Mingyao Liu, MD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1017-1018. doi:10.1001/jamainternmed.2021.0392

Tocilizumab in Treatment for Patients With COVID-19

Jean-François Rossi, MD, PhD; Hao-Chun Chiang, PhD; Bernard Klein, MD, PhD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1018-1019. doi:10.1001/jamainternmed.2021.0395

Tocilizumab in Treatment for Patients With COVID-19

Lucy C. K. Bell, MB, BS, PhD; Gabriele Pollara, MB, BS, PhD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1019. doi:10.1001/jamainternmed.2021.0401

Tocilizumab in Treatment for Patients With COVID-19鈥擱eply

Carlo Salvarani, MD; Marco Massari, MD; Nicola Facciolongo, MD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1019-1020. doi:10.1001/jamainternmed.2021.0404

Tocilizumab in Treatment for Patients With COVID-19鈥擱eply

Olivier Hermine, MD, PhD; Xavier Mariette, MD, PhD; Philippe Ravaud, MD, PhD
Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1020-1021. doi:10.1001/jamainternmed.2021.0407
Correction

Addition of Group Members Supplement

Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1021. doi:10.1001/jamainternmed.2021.1229

Errors in Group Information Supplement

Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1021. doi:10.1001/jamainternmed.2021.2155

Error in Sample Size

Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):1021. doi:10.1001/jamainternmed.2021.3845
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2021;181(7):894. doi:10.1001/jamainternmed.2020.5279
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