Leticia A. Deveza, MD, PhD; Sarah R. Robbins, PhD; Vicky Duong, BSc (Hons); et al.
free access
JAMA Intern Med. 2021;181(4):429-438. doi:10.1001/jamainternmed.2020.7101
This randomized clinical trial determines the efficacy of a 6-week combination of conservative treatments vs an education comparator for people with thumb base osteoarthritis.
Orestis A. Panagiotou, MD, PhD; Cyrus M. Kosar, MA; Elizabeth M. White, PhD, APRN; et al.
free access
JAMA Intern Med. 2021;181(4):439-448. doi:10.1001/jamainternmed.2020.7968
This cohort study examines risk factors for 30-day all-cause mortality among US nursing home residents with COVID-19.
Kristina L. Bajema, MD, MSc; Ryan E. Wiegand, MS; Kendra Cuffe, MPH; et al.
open access
JAMA Intern Med. 2021;181(4):450-460. doi:10.1001/jamainternmed.2020.7976
This cross-sectional study examines the prevalence of persons with SARS-CoV-2 antibodies across the US and changes from July to September 2020.
Phillip W. Clapp, PhD; Emily E. Sickbert-Bennett, PhD, MS; James M. Samet, PhD, MPH; et al.
free access
JAMA Intern Med. 2021;181(4):463-469. doi:10.1001/jamainternmed.2020.8168
This comparative study examines the fitted filtration efficiency of 7 consumer-grade face masks and 5 medical procedure mask modifications.
David A. Asch, MD, MBA; Natalie E. Sheils, PhD; Md Nazmul Islam, PhD, MBA; et al.
open access
JAMA Intern Med. 2021;181(4):471-478. doi:10.1001/jamainternmed.2020.8193
This cohort study examines variations in COVID-19 mortality rates and over the first 6 months of the pandemic.
Farhood Farjah, MD, MPH; Sarah E. Monsell, MS; Michael K. Gould, MD, MS; et al.
free access
JAMA Intern Med. 2021;181(4):480-489. doi:10.1001/jamainternmed.2020.8250
This comparative effectiveness research reports the radiation exposure, adverse events, and health expenditures associated with the varying intensities of lung nodule detection.
Avi Cherla, MSc; Huseyin Naci, MHS, PhD; Aaron S. Kesselheim, MD, JD, MPH; et al.
open access
JAMA Intern Med. 2021;181(4):490-498. doi:10.1001/jamainternmed.2020.8441
This cohort study assesses the concordance between cancer drug indications receiving accelerated approval from the US Food and Drug Administration between 1992 and 2017 and those subsequently authorized for funding through the National Health Service in England.
Daniel E. Meyers, MD, MSc; Kristina Jenei, BSN; Timothy M. Chisamore, MSc; et al.
free access
JAMA Intern Med. 2021;181(4):499-508. doi:10.1001/jamainternmed.2020.8588
This cohort study evaluates the quality of evidence in the drug submission process for provincial reimbursement of the pan-Canadian Oncology Drug Review.
Mary R. Rooney, PhD, MPH; Andreea M. Rawlings, PhD; James S. Pankow, PhD, MPH; et al.
free access
has multimedia
has audio
JAMA Intern Med. 2021;181(4):511-519. doi:10.1001/jamainternmed.2020.8774
This cohort study of older adults without diabetes compares different prediabetes definitions and characterizes the risks of prediabetes and diabetes in this population.
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Video:
Screening for Prediabetes
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Podcast:
Risk of Progression to Diabetes Among Older Adults With Prediabetes
Harinder Singh Chahal, PharmD, MSc; Sanjana Mukherjee, PhD, MSc; Daniel W. Sigelman, JD; et al.
open access
JAMA Intern Med. 2021;181(4):522-529. doi:10.1001/jamainternmed.2020.8866
This cross-sectional study analyzes the US Food and Drug Administration’s reasons for issuing refuse-to-file letters and assesses public transparency of refuse-to-file letters and their contents.
Susan M. McCurry, PhD; Weiwei Zhu, MS; Michael Von Korff, ScD; et al.
free access
JAMA Intern Med. 2021;181(4):530-538. doi:10.1001/jamainternmed.2020.9049
This randomized clinical trial evaluates the effectiveness of a telephone cognitive behavioral therapy for insomnia vs education-only control in older adults with moderate to severe osteoarthritis pain.