Thomas A. Wadden, PhD; Gregory K. Brown, PhD; Christina Egebjerg, PhD; et al.
open access
JAMA Intern Med. 2024;184(11):1290-1300. doi:10.1001/jamainternmed.2024.4346
This post hoc analysis of 4 randomized clinical trials evaluates the psychiatric safety of subcutaneous semaglutide, 2.4 mg, once weekly in people with obesity or overweight without known major psychopathology.
Peter Ueda, MD, PhD; Jonas Söderling, PhD; Viktor Wintzell, PhD; et al.
open access
JAMA Intern Med. 2024;184(11):1301-1312. doi:10.1001/jamainternmed.2024.4369
This cohort study assesses the association between use of glucagon-like peptide-1 receptor agonists and the risk of suicide death in routine clinical practice.
Fasiha Kanwal, MD, MSHS; Jennifer R. Kramer, MPH, PhD; Liang Li, PhD; et al.
has audio
JAMA Intern Med. 2024;184(11):1314-1323. doi:10.1001/jamainternmed.2024.4661
This cohort study aims to determine whether use of glucagon-like peptide 1 receptor agonists are associated with lower risk of developing cirrhosis and its complications, including decompensation and hepatocellular cancer, among patients with metabolic dysfunction-associated steatotic liver disease.
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Podcast:
GLP-1 Receptor Agonists and Cirrhosis in Metabolic Dysfunction-Associated Steatotic Liver Disease
Health Equity
Sebastian Linde, PhD; Leonard E. Egede, MD, MS, FACP
JAMA Intern Med. 2024;184(11):1324-1328. doi:10.1001/jamainternmed.2024.4998
This study explores whether individuals who resided in US Home Owners’ Loan Corporation redlined neighborhoods in 1940 had lower life expectancy later in life compared with individuals who resided in neighborhoods that were not redlined.
Health Equity
John R. Bassler, MS; Lauren Ostrenga, MPH; Emily B. Levitan, ScD; et al.
JAMA Intern Med. 2024;184(11):1329-1337. doi:10.1001/jamainternmed.2024.5003
This study assesses the effect of redlining on time to viral suppression among people newly diagnosed with HIV in New Orleans, Louisiana.
Less Is More
Katie Fitzgerald Jones, PhD, ACHPN; Kelly Stolzmann, MS; Jolie Wormwood, PhD; et al.
JAMA Intern Med. 2024;184(11):1339-1346. doi:10.1001/jamainternmed.2024.4739
This pragmatic nonrandomized multisite clinical trial examines the effectiveness of patient-directed educational materials provided before primary care appointments in promoting deprescribing for low-benefit and high-risk medication groups.
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Editorial
Educational Brochures for Deprescribing
Timothy S. Anderson, MD, MAS
JAMA Intern Med
Less Is More
Bocheng Jing, MS; Xiaojuan Liu, MS; Laura A. Graham, PhD; et al.
JAMA Intern Med. 2024;184(11):1347-1355. doi:10.1001/jamainternmed.2024.4851
This cohort study investigates the association between antihypertensive deprescribing and changes in cognitive function in nursing home residents.
Christi S. Ulmer, PhD, DBSM; Corrine I. Voils, PhD; Amy S. Jeffreys, MStat; et al.
JAMA Intern Med. 2024;184(11):1356-1364. doi:10.1001/jamainternmed.2024.4419
This randomized clinical trial examines the effectiveness of a nurse-supported, self-directed behavioral insomnia intervention for decreasing insomnia severity and improving sleep outcomes among veterans.
Augusta K. Alwang, MD; Anica C. Law, MD, MS; Elizabeth S. Klings, MD; et al.
JAMA Intern Med. 2024;184(11):1365-1372. doi:10.1001/jamainternmed.2024.4428
This multicenter retrospective cohort study examines the comparative effectiveness of lactated Ringer solution vs normal saline for fluid resuscitation in inpatients with sickle cell disease and vaso-occlusive episodes.
Kimberly G. Blumenthal, MD, MSc; Liam R. Smith, BS; Jushin Teg S. Mann, BS; et al.
JAMA Intern Med. 2024;184(11):1374-1383. doi:10.1001/jamainternmed.2024.4606
This systematic review and meta-analysis evaluates the frequency of reactions to direct penicillin challenges in individuals with penicillin allergy labels across diverse patient populations.