Patric Liang, MD; Jack L. Cronenwett, MD; Eric A. Secemsky, MD; et al.
free access
JAMA Neurol. 2023;80(5):437-444. doi:10.1001/jamaneurol.2023.0285
This cohort study compares risk of 30-day stroke, death, or myocardial infarction or 1-year ipsilateral stroke among patients with standard surgical risk undergoing transcarotid artery revascularization vs carotid endarterectomy.
Xin You Tai, MD; Emma Torzillo, MD; Donald M. Lyall, PhD; et al.
open access
has audio
JAMA Neurol. 2023;80(5):445-454. doi:10.1001/jamaneurol.2023.0339
This cross-sectional study examines data from the UK Biobank to explore the association between focal epilepsy compared with stroke or migraine and the risk of developing dementia and how that risk is affected by modifiable cardiovascular risk factors.
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Podcast:
Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
Zekun Zheng, MD; Yanling Lv, MD; Shuang Rong, PhD; et al.
free access
JAMA Neurol. 2023;80(5):455-461. doi:10.1001/jamaneurol.2023.0183
This cohort study attempts to examine the longitudinal association of frailty phenotype with the development of Parkinson disease and to explore the modification role of genetic risk of Parkinson disease in such association.
Gillian T. Coughlan, MS, PhD; Tobey J. Betthauser, PhD; Rory Boyle, PhD; et al.
free access
JAMA Neurol. 2023;80(5):462-473. doi:10.1001/jamaneurol.2023.0455
This cross-sectional study examines the extent to which sex, age at menopause, and hormone therapy use are associated with regional tau at a given level of β-amyloid, both measured with positron emission tomography.
Russell Chabanne, MD, MSc; Thomas Geeraerts, MD, PhD; Marc Begard, MD; et al.
free access
JAMA Neurol. 2023;80(5):474-483. doi:10.1001/jamaneurol.2023.0413
This randomized clinical trial evaluates whether general anesthesia or procedural sedation for anterior circulation large-vessel occlusion acute ischemic stroke thrombectomy is associated with a difference in periprocedural complications and 3-month functional outcome.
Paolo Pierino Mazzone, MSc; Kirsty Mhairi Hogg, MBChB; Christopher J. Weir, PhD; et al.
free access
JAMA Neurol. 2023;80(5):484-494. doi:10.1001/jamaneurol.2023.0148
This systematic review and meta-analysis compares data for women with and without epilepsy to investigate maternal, fetal, and neonatal complications and their associations with epilepsy and use of antiseizure medications.
Lawren VandeVrede, MD, PhD; Renaud La Joie, PhD; Elisabeth H. Thijssen, PhD; et al.
open access
JAMA Neurol. 2023;80(5):495-505. doi:10.1001/jamaneurol.2023.0488
This cohort study evaluated the use of phosphorylated tau217 to discern between Alzheimer disease and frontotemporal lobar degeneration among patients with corticobasal syndrome.
Chia-Yu Hsu, MD; Jeffrey L. Saver, MD; Bruce Ovbiagele, MD; et al.
open access
JAMA Neurol. 2023;80(5):506-515. doi:10.1001/jamaneurol.2023.0218
This meta-analysis and meta-regression of randomized clinical trials evaluates the association of magnitude of differential blood pressure reduction and recurrent stroke in patients with stroke or transient ischemic attack.
Shorena Janelidze, PhD; Nicolas R. Barthélemy, PhD; Yingxin He, PhD; et al.
open access
JAMA Neurol. 2023;80(5):516-522. doi:10.1001/jamaneurol.2023.0199
This cross-sectional study investigates associations of chronic kidney disease with plasma ratios of phosphorylated tau 217 and 181 to the corresponding unphosphorylated peptides in Alzheimer disease.