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October 2024 - July 1959

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Year

Issue

March 2023, Vol 80, No. 3, Pages 224-324

Viewpoint

Cerebral Amyloid Angiopathy—How to Translate Updated Diagnostic Criteria for This Multifaceted Disorder to Clinical Practice?

Abstract Full Text
JAMA Neurol. 2023;80(3):225-226. doi:10.1001/jamaneurol.2022.5060

This Viewpoint discusses recent efforts to update diagnostic criteria for cerebral amyloid angiopathy as well as questions and challenges in counseling patients about prognosis and deciding on optimal treatment.

Challenges and Opportunities for Clinical Trials in Patients With Glioma

Abstract Full Text
JAMA Neurol. 2023;80(3):227-228. doi:10.1001/jamaneurol.2022.4924

This Viewpoint discusses the challenges and opportunities of including patients with glioma in clinical trials.

On the Brain

Stay for the Eulogy

Abstract Full Text
JAMA Neurol. 2023;80(3):229-230. doi:10.1001/jamaneurol.2022.4957

In this essay, the author recounts caring for a patient from primary care clinic to hospice referral and attending the patient’s funeral.

Editorial

Building Evidence on Safety of Thrombolysis for Patients Undergoing Direct Oral Anticoagulant Treatment

Abstract Full Text
JAMA Neurol. 2023;80(3):231-232. doi:10.1001/jamaneurol.2022.4765
Original Investigation

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants

Abstract Full Text
open access
JAMA Neurol. 2023;80(3):233-243. doi:10.1001/jamaneurol.2022.4782

This cohort study evaluates the risk of symptomatic intracranial hemorrhage associated with use of intravenous thrombolysis in patients with recent direct oral anticoagulant ingestion.

Effect of Self-treatment of Recurrent Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial

Abstract Full Text
free access has multimedia
JAMA Neurol. 2023;80(3):244-250. doi:10.1001/jamaneurol.2022.4944

This randomized clinical trial assesses the efficacy of a web-based diagnosis and treatment of benign paroxysmal positional vertigo when it recurs in patients with confirmed and treated benign paroxysmal positional vertigo.

Effects of a Polypill, Aspirin, and the Combination of Both on Cognitive and Functional Outcomes: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2023;80(3):251-259. doi:10.1001/jamaneurol.2022.5088

This randomized clinical trial investigates the effectiveness of a polypill in the reduction of cognitive and functional decline in individuals at intermediate risk of cardiovascular disease.

Head Injury and Long-term Mortality Risk in Community-Dwelling Adults

Abstract Full Text
free access
JAMA Neurol. 2023;80(3):260-269. doi:10.1001/jamaneurol.2022.5024

This cohort study uses Atherosclerosis Risk in Communities study data to evaluate the association of head injury with long-term all-cause mortality risk in adults.

Assessment of Safety of a Fully Implanted Endovascular Brain-Computer Interface for Severe Paralysis in 4 Patients: The Stentrode With Thought-Controlled Digital Switch (SWITCH) Study

Abstract Full Text
free access
JAMA Neurol. 2023;80(3):270-278. doi:10.1001/jamaneurol.2022.4847

This case series assesses the safety of an endovascular brain-computer interface and feasibility of using the system to control a computer by thought.

Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries

Abstract Full Text
open access
JAMA Neurol. 2023;80(3):279-286. doi:10.1001/jamaneurol.2022.5128

This cohort study analyzes age- and sex-specific incidence rates of frontotemporal lobar degeneration–related disorders by phenotype across 9 European countries.

Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis

Abstract Full Text
free access
JAMA Neurol. 2023;80(3):287-297. doi:10.1001/jamaneurol.2022.5250

This cohort study investigates if concentrations of serum glial fibrillary acidic protein and neurofilament light chain are associated with and prognostic for disease progression in patients with multiple sclerosis.

Efficacy and Safety of Proposed Biosimilar Natalizumab (PB006) in Patients With Relapsing-Remitting Multiple Sclerosis: The Antelope Phase 3 Randomized Clinical Trial

Abstract Full Text
open access
JAMA Neurol. 2023;80(3):298-307. doi:10.1001/jamaneurol.2022.5007

This randomized clinical trial evaluates matching efficacy, safety, and immunogenicity between biosimilar natalizumab and reference natalizumab in patients with relapsing-remitting multiple sclerosis.

Review

Management of Trigeminal Autonomic Cephalalgias Including Chronic Cluster: A Review

Abstract Full Text
has active quiz
JAMA Neurol. 2023;80(3):308-319. doi:10.1001/jamaneurol.2022.4804

This narrative review discusses the management of rare trigeminal autonomic cephalalgias over the last 20 years.

Images in Neurology

Tic Status in Tourette Syndrome Due to Depletion of the Deep Brain Stimulation Battery

Abstract Full Text
has active quiz has multimedia
JAMA Neurol. 2023;80(3):320-321. doi:10.1001/jamaneurol.2022.4774

In this case report, a patient with Tourette syndrome was admitted to the emergency department with nonrhythmic, continuous, generalized hyperkinetic movements associated with muscle contractions in the trunk, neck, and upper and lower limbs caused by depletion of the deep brain stimulation battery.

Triple Benign Paroxysmal Positional Vertigo and the Strength of Remote Video-Based Management

Abstract Full Text
has active quiz has multimedia
JAMA Neurol. 2023;80(3):322. doi:10.1001/jamaneurol.2022.4861

This case report describes remote video-based diagnosis and management of triple posttraumatic benign paroxysmal positional vertigo.

JAMA Neurology Clinical Challenge

Severe Cervicodynia in a Patient With Pustules on the Palms

Abstract Full Text
has active quiz
JAMA Neurol. 2023;80(3):323-324. doi:10.1001/jamaneurol.2022.4739

A 51-year-old man had severe neck pain and pustules on both hands. What is your diagnosis?

JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2023;80(3):224. doi:10.1001/jamaneurol.2022.4073
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