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Caring for the Critically Ill Patient

Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial

• Video: Conference Presentation: Effect of Stress Ulcer Prophylaxis With PPIs vs H2RBs on Mortality in Ventilated ICU Patients

• Editorial
  Proton Pump Inhibitors vs Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis in Critically Ill Patients: Issues of Interpretability in Pragmatic Trials
  Todd W. Rice, MD, MSc; Sunil Kripalani, MD, MSc; Christopher J. Lindsell, PhD
  JAMA

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

• Editorial
  Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease?
  Sadiya S. Khan, MD, MSc; Richard Cooper, MD; Philip Greenland, MD
  JAMA

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

• Editorial
  Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease?
  Sadiya S. Khan, MD, MSc; Richard Cooper, MD; Philip Greenland, MD
  JAMA

Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer