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October 2017, Vol 171, No. 10, Pages 927-1024

In This Issue of JAMA Pediatrics

Highlights

Abstract Full Text
free access has audio
JAMA Pediatr. 2017;171(10):927. doi:10.1001/jamapediatrics.2016.3135
Viewpoint

Communicating About Vaccines in a Fact-Resistant World

Abstract Full Text
JAMA Pediatr. 2017;171(10):929-930. doi:10.1001/jamapediatrics.2017.2219

This Viewpoint discusses ways to guide productive vaccine discussions in the clinic.

Why It Is So Hard to Talk About Overuse in Pediatrics and Why It Matters

Abstract Full Text
JAMA Pediatr. 2017;171(10):931-932. doi:10.1001/jamapediatrics.2017.2239

This Viewpoint discusses why pediatricians are reluctant to embrace the topic of medical overuse.

Building Stronger Online Communities Through the Creation of Facebook-Integrated Health Applications

Abstract Full Text
JAMA Pediatr. 2017;171(10):933-934. doi:10.1001/jamapediatrics.2017.2300

This Viewpoint proposes the creation of Facebook-integrated health applications to strengthen online communities focused on health care and particularly pediatric chronic diseases.

The Tragic Case of Charlie Gard

Abstract Full Text
JAMA Pediatr. 2017;171(10):935-936. doi:10.1001/jamapediatrics.2017.3079

This Viewpoint summarizes the case of Charlie Gard and discusses implications of the court decision.

Charlie Gard and the Limits of Best Interests

Abstract Full Text
JAMA Pediatr. 2017;171(10):937-938. doi:10.1001/jamapediatrics.2017.3076

This Viewpoint discusses a court case of an infant with infantile-onset mitochondiral DNA depletion syndrome whose parents wished to continue experimental treatment and outlines the limits of the best interest standard.

On My Mind

A Personal Perspective on Disability: Between the Words

Abstract Full Text
JAMA Pediatr. 2017;171(10):939. doi:10.1001/jamapediatrics.2017.2242
Editorial

Fetal Alcohol Spectrum Disorder—High Rates, High Needs, High Time for Action

Abstract Full Text
JAMA Pediatr. 2017;171(10):940-941. doi:10.1001/jamapediatrics.2017.2232

Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury

Abstract Full Text
JAMA Pediatr. 2017;171(10):942-943. doi:10.1001/jamapediatrics.2017.2390

Using Disease Epidemiology to Optimize Immunization Schedules

Abstract Full Text
JAMA Pediatr. 2017;171(10):944-945. doi:10.1001/jamapediatrics.2017.2375
Original Investigation

Global Prevalence of Fetal Alcohol Spectrum Disorder Among Children and Youth: A Systematic Review and Meta-analysis

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):948-956. doi:10.1001/jamapediatrics.2017.1919

This systematic review and meta-analysis estimates prevalence of fetal alcohol spectrum disorder among children and youth in the general population by country and international region.

Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):957-964. doi:10.1001/jamapediatrics.2017.2135

This multicenter cohort study examines the procedural sedation practices, adverse events, and risk factors for children undergoing painful procedures in Canadian emergency departments.

Caring for the Critically Ill Patient

Functional Outcome After Intracranial Pressure Monitoring for Children With Severe Traumatic Brain Injury

Abstract Full Text
free access has audio
JAMA Pediatr. 2017;171(10):965-971. doi:10.1001/jamapediatrics.2017.2127

This propensity-weighted analysis uses data from 30 US children’s hospitals to test the hypothesis that intracranial pressure monitoring is associated with improved functional survival of children with severe traumatic brain injury.

Association of Neonatal Glycemia With Neurodevelopmental Outcomes at 4.5 Years

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):972-983. doi:10.1001/jamapediatrics.2017.1579

This cohort study investigates the association between neurodevelopment at 4.5 years and the severity and frequency of neonatal hypoglycemia.

Use of Laboratory Markers in Addition to Symptoms for Diagnosis of Inflammatory Bowel Disease in Children: A Meta-analysis of Individual Patient Data

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):984-991. doi:10.1001/jamapediatrics.2017.1736

This meta-analysis of 1120 pediatric patients examines whether blood tests and fecal calprotectin aid in the diagnosis of inflammatory bowel disease.

Evaluation of Combination Measles-Mumps-Rubella-Varicella Vaccine Introduction in Australia

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):992-998. doi:10.1001/jamapediatrics.2017.1965

This population-based study examines the incidence of febrile seizures associated with combination measles-mumps-rubella-varicella vaccine in toddlers.

Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy

Abstract Full Text
free access online only
JAMA Pediatr. 2017;171(10):e172222. doi:10.1001/jamapediatrics.2017.2222

This birth surveillance study compares the risk for selected birth outcomes by maternal antiretroviral therapy regimen among pregnant women with HIV infection in Botswana.

Caring for the Critically Ill Patient

Adaptation and Validation of a Pediatric Sequential Organ Failure Assessment Score and Evaluation of the Sepsis-3 Definitions in Critically Ill Children

Abstract Full Text
free access online only
JAMA Pediatr. 2017;171(10):e172352. doi:10.1001/jamapediatrics.2017.2352

This cohort study assesses the validity of a pediatric version of the Sequential Organ Failure Assessment (SOFA) scoring system compared with the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) to examine the in-hospital mortality of critically ill children with confirmed or suspected infection and sepsis.

Review

The Role of Environmental Factors in the Pathogenesis of Inflammatory Bowel Diseases: A Review

Abstract Full Text
JAMA Pediatr. 2017;171(10):999-1005. doi:10.1001/jamapediatrics.2017.2571

This review provides an overview of data suggesting how different environmental factors may modulate the risk of developing inflammatory bowel diseases including diet, smoking, lifestyle choices, enteric infections, appendectomy, air pollution, and the use of medications, especially antibiotics.

From the ÌÇÐÄvlog

Brief Therapy for Anxiety and Depression in the Pediatric Primary Care Setting: Implications and Next Steps

Abstract Full Text
JAMA Pediatr. 2017;171(10):1006-1007. doi:10.1001/jamapediatrics.2017.2854

This commentary discusses a study published in JAMA Psychiatry that examined whether a pediatrics-based behavioral intervention targeting anxiety and depression improved clinical outcome compared with referral to outpatient community mental health care.

JAMA Pediatrics Clinical Challenge

Adolescent With Pain and Necrosis Following Intramuscular Injection

Abstract Full Text
JAMA Pediatr. 2017;171(10):1008-1009. doi:10.1001/jamapediatrics.2017.1881

A 15-year-old boy presented to a hospital with pain and purpura of his left thigh after an intramuscular injection. What is your diagnosis?

JAMA Pediatrics Patient Page

How to Talk to Your Children About Tragedies in the News

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):1024. doi:10.1001/jamapediatrics.2017.2351
Research Letter

Epidemiology of Sepsis Among Adolescents at Community Hospital Emergency Departments: Implications for Rory’s Regulations

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):1011-1012. doi:10.1001/jamapediatrics.2017.1915

This study examines the electronic health records of healthy adolescents who presented with signs and symptoms of sepsis to 12 community hospital emergency departments in southwestern Pennsylvania.

Use of Oxyhemoglobin Saturation, Rather Than Oxygen Tension, as a Marker of Oxygenation in Cyanotic Patients

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):1012-1014. doi:10.1001/jamapediatrics.2017.2213

This study analyzes clinically indicated arterial blood gas values from patients with cyanotic congenital heart disease to determine whether oxyhemoglobin saturation or arterial oxygen tension provides a better measure of oxygenation.

Comment & Response

Influenza A Infections in Infants of Vaccinated and Unvaccinated Mothers

Abstract Full Text
JAMA Pediatr. 2017;171(10):1014-1015. doi:10.1001/jamapediatrics.2017.2391

Influenza A Infections in Infants of Vaccinated and Unvaccinated Mothers—Reply

Abstract Full Text
JAMA Pediatr. 2017;171(10):1015. doi:10.1001/jamapediatrics.2017.2394

Early-Onset Sepsis Calculator—Risk of Delaying Treatment—Reply

Abstract Full Text
JAMA Pediatr. 2017;171(10):1015-1016. doi:10.1001/jamapediatrics.2017.2467

Early-Onset Sepsis Calculator—Risk of Delaying Treatment

Abstract Full Text
JAMA Pediatr. 2017;171(10):1015. doi:10.1001/jamapediatrics.2017.2476

The UK Royal College of Paediatrics and Child Health’s Policy on Funding From Commercial Organizations

Abstract Full Text
JAMA Pediatr. 2017;171(10):1016-1017. doi:10.1001/jamapediatrics.2017.2470

Neurodevelopmental Outcome in Relation to Treatment of Patent Ductus Arteriosus

Abstract Full Text
JAMA Pediatr. 2017;171(10):1017-1018. doi:10.1001/jamapediatrics.2017.2597

Neurodevelopmental Outcome in Relation to Treatment of Patent Ductus Arteriosus

Abstract Full Text
JAMA Pediatr. 2017;171(10):1018. doi:10.1001/jamapediatrics.2017.2612

Neurodevelopmental Outcome in Relation to Treatment of Patent Ductus Arteriosus—Reply

Abstract Full Text
JAMA Pediatr. 2017;171(10):1018-1019. doi:10.1001/jamapediatrics.2017.2615
Correction

Addition of Open Access, Funding/Support, and Role of Funder/Sponsor Information

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):1019. doi:10.1001/jamapediatrics.2017.2732
JAMA Pediatrics Masthead

JAMA Pediatrics

Abstract Full Text
free access
JAMA Pediatr. 2017;171(10):928-929. doi:10.1001/jamapediatrics.2016.3136
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