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September 2024 - January 1929

Decade

Year

Issue

September 2024, Vol 142, No. 9, Pages 788-887

Original Investigation

Filgotinib in Active Noninfectious Uveitis: The HUMBOLDT Randomized Clinical Trial

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):789-797. doi:10.1001/jamaophthalmol.2024.2439

This randomized clinical trial investigates the efficacy and safety of filgotinib in patients with active noninfectious uveitis.

Development and Evaluation of a Retrieval-Augmented Large Language Model Framework for Ophthalmology

Abstract Full Text
open access
JAMA Ophthalmol. 2024;142(9):798-805. doi:10.1001/jamaophthalmol.2024.2513

This quality improvement study discusses the challenges of knowledge inaccuracies and data privacy issues when using large language models in ophthalmology and how to overcome them.

Severe Spaceflight-Associated Neuro-Ocular Syndrome in an Astronaut With 2 Predisposing Factors

Abstract Full Text
has audio
JAMA Ophthalmol. 2024;142(9):808-817. doi:10.1001/jamaophthalmol.2024.2385

This case report investigates why a female astronaut presented with more severe symptoms of spaceflight-associated neuro-ocular syndrome than previous astronauts of either sex.

Guttae Morphology After Cultured Corneal Endothelial Cell Transplant in Fuchs Endothelial Corneal Dystrophy

Abstract Full Text
has multimedia
JAMA Ophthalmol. 2024;142(9):818-826. doi:10.1001/jamaophthalmol.2024.2718

This case series analyzes the presence of guttae in patients with Fuchs endothelial corneal dystrophy after surgical removal and cultured corneal endothelial cell transplant to determine whether guttae can be removed without Descemet stripping.

Endophthalmitis Rates and Types of Treatments After Intraocular Procedures

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):827-834. doi:10.1001/jamaophthalmol.2024.2749

This cohort study examines 20 years of data to determine how rates of endophthalmitis after intraocular procedures have changed over time and how the treatment of those patients has changed.

Vitrectomy as an Adjunct to Treat-and-Extend Anti-VEGF Injections for Diabetic Macular Edema: The Vitrectomy in Diabetic Macular Oedema (VIDEO) Randomized Clinical Trial

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):837-844. doi:10.1001/jamaophthalmol.2024.2777

This randomized clinical trial examined rates of recruitment and efficacy outcomes of vitrectomy plus internal limiting membrane peeling adjunctive to a treat-and-extend anti–vascular endothelial growth factor (VEGF) injection regimen for diabetic macular edema.

Neighborhood-Level Social Determinants of Health and Presenting Characteristics for Rhegmatogenous Retinal Detachments

Abstract Full Text
has audio
JAMA Ophthalmol. 2024;142(9):845-854. doi:10.1001/jamaophthalmol.2024.2889

This cohort study investigates the association between neighborhood-level social determinants of health and severity of rhegmatogenous retinal detachments at presentation.

Ultra-Widefield and Early Treatment Diabetic Retinopathy Study 7-Field Grading of Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):856-863. doi:10.1001/jamaophthalmol.2024.2890

This cross-sectional study evaluates ultra-widefield vs Early Treatment Diabetic Retinopathy Study 7-field imaging for the capture of diabetic retinopathy.

Biomarker Detection and Validation for Corneal Involvement in Patients With Acute Infectious Conjunctivitis

Abstract Full Text
open access has audio
JAMA Ophthalmol. 2024;142(9):865-871. doi:10.1001/jamaophthalmol.2024.2891

This cross-sectional study evaluates potential biomarkers in patients with acute infectious conjunctivitis.

Brief Report

Vitreoretinopathy in Asymptomatic Children With CTNNB1 Syndrome

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):874-878. doi:10.1001/jamaophthalmol.2024.2847

This case series of 11 patients with CTNNB1 syndrome reports the presence of familial exudative vitreoretinonpathy detected via fluorescein angiography under anesthesia, which was previously undetected on ophthalmoscopic examination.

Invited Commentary

Need for Custom Artificial Intelligence Chatbots in Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(9):806-807. doi:10.1001/jamaophthalmol.2024.2738

Changes in Rates of Postprocedural Endophthalmitis and Treatments

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):835-836. doi:10.1001/jamaophthalmol.2024.2805

Implications of Neighborhood- and Patient-Level Factors for Eye Care

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):854-855. doi:10.1001/jamaophthalmol.2024.3066

Health and the 2024 US Election

Moving Forward to a Wider Retinal Field of View

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):863-864. doi:10.1001/jamaophthalmol.2024.3071

Molecular Sequencing and Biomarkers in Acute Infectious Conjunctivitis

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):872-873. doi:10.1001/jamaophthalmol.2024.3091

Genetic Testing for Rare Retinal Diseases in Telomere Biology Disorders

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):878-879. doi:10.1001/jamaophthalmol.2024.2947
JAMA Ophthalmology Clinical Challenge

Acute Bilateral Periorbital Edema in a Psychiatric Patient

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2024;142(9):880-881. doi:10.1001/jamaophthalmol.2024.2815

An older patient with history of alcohol use disorder was admitted for altered mental status and received valproic acid and olanzapine from the psychiatric service. On hospital day 2, the patient acutely developed bilateral periorbital edema. What would you do next?

Ophthalmic Images

Thirteen-Year Follow-Up of Conjunctival Amyloidosis

Abstract Full Text
online only has active quiz
JAMA Ophthalmol. 2024;142(9):e242662. doi:10.1001/jamaophthalmol.2024.2662

This case report discusses a diagnosis of conjunctival amyloidosis in an otherwise asymptomatic male aged 71 years with 13-year follow-up.

Synchysis Scintillans After Long-Standing History of Retinal Detachment

Abstract Full Text
online only has active quiz
JAMA Ophthalmol. 2024;142(9):e242945. doi:10.1001/jamaophthalmol.2024.2945

This case report discusses a diagnosis of synchysis scintillans in a patient aged 77 years with a history of retinal detachment and no light perception vision in the left eye.

Real-Time Visualization of a Transient Retinal Embolus

Abstract Full Text
online only has active quiz
JAMA Ophthalmol. 2024;142(9):e242946. doi:10.1001/jamaophthalmol.2024.2946

This case report describes the real-time imaging of a transient retinal embolus in a patient experiencing episodes of monocular vision loss.

Comment & Response

Impact of Pediatric Instrument-Based Vision Screening

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):882. doi:10.1001/jamaophthalmol.2024.2256

Impact of Pediatric Instrument-Based Vision Screening—Reply

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):882-883. doi:10.1001/jamaophthalmol.2024.2259

Challenges of Integrating Chatbot Use in Ophthalmology Diagnostics

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):883-884. doi:10.1001/jamaophthalmol.2024.2303

Challenges of Integrating Chatbot Use in Ophthalmology Diagnostics—Reply

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):884. doi:10.1001/jamaophthalmol.2024.2306

Challenges in Assessing Dose-Dependent Atropine for Myopia

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):884-885. doi:10.1001/jamaophthalmol.2024.3074

Challenges in Assessing Dose-Dependent Atropine for Myopia—Reply

Abstract Full Text
JAMA Ophthalmol. 2024;142(9):886-887. doi:10.1001/jamaophthalmol.2024.3078
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(9):788. doi:10.1001/jamaophthalmol.2023.4598
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