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October 2024 - January 1929

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January 2019, Vol 137, No. 1, Pages 1-121

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):1. doi:10.1001/jamaophthalmol.2018.4457
Original Investigation

Prevalence and Associated Factors of Uncorrected Refractive Error in Older Adults in a Population-Based Study in France

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):3-11. doi:10.1001/jamaophthalmol.2018.4229

This cross-sectional study estimates the prevalence of uncorrected refractive error in older adults, particularly in those with age-related eye disease and who are unable to attend an outpatient clinic, and identifies the factors associated with uncorrected refractive error.

Association of Angle Width With Progression of Normal-Tension Glaucoma: A Minimum 7-Year Follow-up Study

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):13-20. doi:10.1001/jamaophthalmol.2018.4333

This study determines whether anterior chamber angle width plays any role in normal-tension glaucoma progression.

Ocular Antihypertensive Medication Use After iStent Implantation Concurrent With Cataract Surgery vs Cataract Surgery Alone in a Large US Health Care Claims Database

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):21-27. doi:10.1001/jamaophthalmol.2018.4461

This study determines whether implantation of the iStent concurrent with cataract surgery is associated with reduced use of ocular antihypertensive medications in a US health care claims database.

Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based Studies

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):28-35. doi:10.1001/jamaophthalmol.2018.4477

This cross-sectional study of population-based and registry-based studies examines the penetrance and association of myocilin (MYOC) gene p.Gln368Ter variant with glaucoma and ocular hypertension.

Association of Disorganization of Retinal Inner Layers With Visual Acuity Response to Anti–Vascular Endothelial Growth Factor Therapy for Macular Edema Secondary to Retinal Vein Occlusion

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):38-46. doi:10.1001/jamaophthalmol.2018.4484

This study examines whether disorganization of inner retinal layers at baseline and after treatment is a biomarker of visual acuity in patients with retinal vein occlusion.

Changes in the Incidence of Eye Trauma Hospitalizations in the United States From 2001 Through 2014

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):48-56. doi:10.1001/jamaophthalmol.2018.4685

This cohort study uses data from the National Inpatient Sample to assess changes in the incidence of eye trauma hospitalizations in the United States from 2001 through 2014.

Association of Cataract Surgical Outcomes With Late Surgeon Career Stages: A Population-Based Cohort Study

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):58-64. doi:10.1001/jamaophthalmol.2018.4886

This population-based cohort study examines the association between cataract surgical adverse events and late surgeon career stage in adults undergoing cataract surgery in Canada.

Comparison of Early Treatment Diabetic Retinopathy Study Standard 7-Field Imaging With Ultrawide-Field Imaging for Determining Severity of Diabetic Retinopathy

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):65-73. doi:10.1001/jamaophthalmol.2018.4982

This cross-sectional study analyzes severity of diabetic retinopathy in patients whose eyes were examined via the Early Treatment Diabetic Retinopathy Study (ETDRS) 7-field imaging and ultrawide-field (UWF) imaging techniques.

Clinical Features, Metastasis, and Survival in Patients Younger Than 21 Years With Posterior Uveal Melanoma

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):75-81. doi:10.1001/jamaophthalmol.2018.5132

This cohort study analyzes clinical records from 1980 to 2013 to identify rates of metastasis and survival in patients younger than 21 years with posterior uveal melanoma.

Brief Report

Evidence That Leonardo da Vinci Had Strabismus

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):82-86. doi:10.1001/jamaophthalmol.2018.3833

This study assesses 6 putative portraits and self-portraits of Leonardo da Vinci to provide evidence that the artist had strabismus.

Association of Intravitreal Injections With Blood Pressure Increase: The Following Excitement and Anxiety Response Under Intravitreal Injection Study

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):87-90. doi:10.1001/jamaophthalmol.2018.4892

This study investigates whether blood pressure fluctuates during intravitreal injections.

Association of Somatic GNAQ Mutation With Capillary Malformations in a Case of Choroidal Hemangioma

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):91-95. doi:10.1001/jamaophthalmol.2018.5141

This case study investigates the presence of the GNAQ R183Q mutation in the choroidal vessels of a patient with Sturge-Weber syndrome.

Association of Cancer Immunotherapy With Acute Macular Neuroretinopathy and Diffuse Retinal Venulitis

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):96-100. doi:10.1001/jamaophthalmol.2018.5191

This case series describes 2 patients who developed ophthalmologic events after treatment with the programmed death 1 axis inhibitor, atezolizumab.

Invited Commentary

On Aging and Vision: No Time to Lament

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):11-12. doi:10.1001/jamaophthalmol.2018.4207

Penetrance of Myocilin Mutations—Who Gets Glaucoma?

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):35-37. doi:10.1001/jamaophthalmol.2018.4470

Disorganization of Retinal Inner Layers and the Importance of Setting Boundaries

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):46-47. doi:10.1001/jamaophthalmol.2018.4516

National Trends in Ocular Injury: Differing Studies, Common Call to Action

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):56-57. doi:10.1001/jamaophthalmol.2018.4694

Comparing the Early Treatment Diabetic Retinopathy Study 7-Field System With Ultrawide-Field Imaging

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):73-74. doi:10.1001/jamaophthalmol.2018.4971
JAMA Ophthalmology Clinical Challenge

Bilateral Optic Atrophy in an Adolescent Male Patient

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):101-102. doi:10.1001/jamaophthalmol.2018.2594

A boy in his late teens with short stature presented with gradual loss of vision in both eyes since 8 years of age, a diagnosis of type 1 diabetes at 10 years of age, hearing loss during the past 2 years, hypochondroplasia, alopecia, and generalized hypotonia. What would you do next?

A 2-Year History of Diplopia, Optic Disc Edema, and Amaurosis

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):103-104. doi:10.1001/jamaophthalmol.2018.2604

A man in his 50s presented with a 2-year history of optic disc edema in the right eye, double vision, and graying of vision; examination found prominent chronic-appearing optic disc edema in the right eye and superior greater than inferior peripheral field loss in the right eye. What would you do next?

Middle-aged Man With Bilateral Subretinal Fluid

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):105-106. doi:10.1001/jamaophthalmol.2018.2759

A middle-aged man presents with painless blurry vision in the left eye and bilateral subretinal fluid in the macula. Late-phase fluorescein angiography reveals multifocal pinpoint areas of hyperfluorescence with mild leakage. What would you do next?

Progressive Bilateral Cecocentral Scotomata

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):107-108. doi:10.1001/jamaophthalmol.2018.4144

A 60-year-old man presents with a 6-month history of progressive painless visual loss, photophobia, and color vision impairment in both eyes. What would you do next?

Night Blindness, Ring Scotoma, and a Nonrecordable Electroretinogram in an Elderly Woman

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):109-110. doi:10.1001/jamaophthalmol.2018.3408

A woman in her 70s reports difficulty seeing in dimly lit settings for the past 6 years and is referred for evaluation. Her best-corrected visual acuity is 20/40 OD and 20/25 OS, and spectral-domain optical coherence tomography shows complete loss of photoreceptors outside the fovea. What would you do next?

Rare Complication of Sclerochoroidal Calcifications

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):111-112. doi:10.1001/jamaophthalmol.2018.2457

This case report describes a woman in her mid-70s who was referred for bilateral choroidal lesions and, on presentation, described her vision as blurred in the left eye. Confrontation visual fields revealed a deficit in the inferotemporal quadrant of the left eye, and fluorescein and indocyanine angiography demonstrated leakage in the area of subretinal hemorrhage in the left eye. What would you do next?

Research Letter

Accuracy of Freely Available Information About Rhegmatogenous Retinal Detachment on the Internet

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):113-114. doi:10.1001/jamaophthalmol.2018.4682

This study uses a list of 17 predefined questions to examine the information on rhegmatogenous retinal detachment available to patients via 6 public websites.

Association of Cognitive Impairment and Dementia With Receipt of Cataract Surgery Among Community-Dwelling Medicare Beneficiaries

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):114-117. doi:10.1001/jamaophthalmol.2018.5138

This study uses data from the National Health and Aging Trends Study to determine the association of cognitive impairment and dementia with receipt of cataract surgery among community-dwelling Medicare beneficiaries.

Observation

Association of Transient Colorblindness With Sildenafil and Tadalafil

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):117-118. doi:10.1001/jamaophthalmol.2018.4716

This case report describes a 57-year-old man with transient colorblindness that was associated with taking sildenafil and tadalafil.

Ophthalmic Images

A Clear Disc Deep in the Cornea Stroma

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):e183414. doi:10.1001/jamaophthalmol.2018.3414

This case report describes a 94-year-old man who presented for a routine examination without any eye concerns despite having a synthetic corneal implant in place for more than 25 years.

Optic Disc Pit With Peripapillary Retinoschisis Misdiagnosed as Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):e183851. doi:10.1001/jamaophthalmol.2018.3851

A 63-year-old woman who had received a previous diagnosis of unilateral normal tension glaucoma attended for follow-up. Optical coherence tomography revealed a peripapillary schitic cavity communicating with the pit excavation

Association of Ultrawide-Field Findings in Proliferative Retinopathy With Systemic Lupus Erythematosus

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):e183861. doi:10.1001/jamaophthalmol.2018.3861

This case report describes ultrawide-field fluorescein angiography findings of retinal neovascularization in an African American patient in their 30s with a history of systemic lupus erythematosus.

Purtscher-Like Retinopathy in Hemolytic Uremic Syndrome

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):e183911. doi:10.1001/jamaophthalmol.2018.3911

A 30-year-old previously healthy man presented with 1 month of rapidly declining vision in both eyes following acute gastroenteritis.

Comment & Response

Language Bias and Methodological Issues in Determining Reliable Evidence for Systematic Reviews

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):118-119. doi:10.1001/jamaophthalmol.2018.4945

Programming Error Led to Underestimate of Effect Sizes in Study of Association of Maternal Preeclampsia and Risk of Infant Retinopathy of Prematurity

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):119. doi:10.1001/jamaophthalmol.2018.5055

Reducing the Disclosure Effect in the Vitreoretinal Fellowship Match

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):119-120. doi:10.1001/jamaophthalmol.2018.4990

Reducing the Disclosure Effect in the Vitreoretinal Fellowship Match—Reply

Abstract Full Text
JAMA Ophthalmol. 2019;137(1):120-121. doi:10.1001/jamaophthalmol.2018.4993
Correction

Incorrect Description of Events Leading to Presentation to Clinic

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):121. doi:10.1001/jamaophthalmol.2018.5407

Pervasive Errors in the Key Points, Abstract, Results, Discussion, Table 3, and eTable in the Supplement

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):121. doi:10.1001/jamaophthalmol.2018.5352

Error in Figure

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):121. doi:10.1001/jamaophthalmol.2018.5598
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2019;137(1):2. doi:10.1001/jamaophthalmol.2018.4458
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