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November 2024, Vol 142, No. 11, Pages 992-1098

Viewpoint

Untreated Vision Loss as a Modifiable Dementia Risk Factor

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):993-994. doi:10.1001/jamaophthalmol.2024.3991

This Viewpoint discusses vision impairment as a modifiable dementia risk factor.

Diabetic Retinopathy in Youths—A Potentially Unappreciated Public Health Catastrophe

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):995-996. doi:10.1001/jamaophthalmol.2024.3877

This Viewpoint discusses the prevalence of youth-onset diabetes and the associated rates of diabetic retinopathy and addresses the need for surveillance of patients with youth-onset diabetes.

Original Investigation

Incidence and Risk of Depressive Disorder in Patients With Retinitis Pigmentosa

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):997-1004. doi:10.1001/jamaophthalmol.2024.3641

This Korean population-based cohort study evaluated the incidence rates and risks of depressive disorder in patients with retinitis pigmentosa.

A Competition for the Diagnosis of Myopic Maculopathy by Artificial Intelligence Algorithms

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(11):1006-1015. doi:10.1001/jamaophthalmol.2024.3707

This diagnostic study details the results of an international competition to develop automated deep learning and artificial intelligence algorithms for classification and segmentation of myopic maculopathy and compares the algorithms’ performance with that of ophthalmologists.

Potential Gaps in Eye Care Based on Evaluation of Federally Qualified Health Centers

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1018-1026. doi:10.1001/jamaophthalmol.2024.3569

This cross-sectional study examines whether federally qualified health centers in Florida offer eye care services, where the services are available, what services are being offered, and who provides them.

Sterile Intraocular Inflammation Associated With Faricimab

Abstract Full Text
open access
JAMA Ophthalmol. 2024;142(11):1028-1036. doi:10.1001/jamaophthalmol.2024.3828

This case series study evaluates the characteristics and outcomes of sterile intraocular inflammation after injection of faricimab to treat neovascular age-related macular degeneration or diabetic macular edema.

METTL23 Variants and Patients With Normal-Tension Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1037-1045. doi:10.1001/jamaophthalmol.2024.3829

This case-control study evaluates the presence of METTL23 variants in patients with autosomal dominant normal-tension glaucoma.

Prevalence of Glaucoma Among US Adults in 2022

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1046-1053. doi:10.1001/jamaophthalmol.2024.3884

This meta-analysis aimed to develop new multisource composite estimates of the prevalence of glaucoma and vision-affecting glaucoma in the US.

Trends in Retinopathy of Prematurity Among Preterm Infants in California, 2012 to 2021

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1055-1061. doi:10.1001/jamaophthalmol.2024.3909

This cohort study examines changes in the incidence of and racial disparities in retinopathy of prematurity (ROP) among preterm infants in California from 2012 to 2021 in the context of rising rates of ROP among premature infants in the US.

Survival and Health Care Burden of Children With Retinoblastoma in Europe

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1062-1070. doi:10.1001/jamaophthalmol.2024.4140

This cohort study estimates incidence and survival among children with retinoblastoma in 31 European countries as well as the occurrence of second primary tumors.

Deep Learning to Discriminate Arteritic From Nonarteritic Ischemic Optic Neuropathy on Color Images

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(11):1073-1079. doi:10.1001/jamaophthalmol.2024.4269

This cohort study evaluates the use of a deep learning system to discriminate arteritic from nonarteritic anterior ischemic optic neuropathy on color fundus images.

Brief Report

Biallelic Loss-of-Function Variants in UBAP1L and Nonsyndromic Retinal Dystrophies

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1081-1086. doi:10.1001/jamaophthalmol.2024.3836

This case series study investigates the genetic association between UBAP1L variants and retinal dystrophy in humans.

Invited Commentary

Detection and Referral of Depression in Patients With Visual Impairment: A Call for Practical Training and Methods

Abstract Full Text
has audio
JAMA Ophthalmol. 2024;142(11):1004-1005. doi:10.1001/jamaophthalmol.2024.3779

Crowdsourcing for Artificial Intelligence Models in Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(11):1016-1017. doi:10.1001/jamaophthalmol.2024.3778

Federally Qualified Health Centers to Reduce Disparities in Ophthalmology

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1026-1027. doi:10.1001/jamaophthalmol.2024.3837

Glaucoma in the US—Gaps in Data on Racial and Ethnic Minority and Aging Populations

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1053-1054. doi:10.1001/jamaophthalmol.2024.4379

Incidence and Survival Rates in European Children With Retinoblastoma

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1071-1072. doi:10.1001/jamaophthalmol.2024.4268

AI in Ophthalmology

Deep Learning to Improve Diagnosis Must Also Not Do Harm

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(11):1079-1080. doi:10.1001/jamaophthalmol.2024.4377
JAMA Ophthalmology Clinical Challenge

Periocular Swelling, Fever, and Organomegaly in a 4-Year-Old Child

Abstract Full Text
has active quiz
JAMA Ophthalmol. 2024;142(11):1087-1088. doi:10.1001/jamaophthalmol.2024.3871

A child aged 4 years presented with a 3-day history of worsening redness, pain, and swelling over the left lower eyelid and nose. Visual acuity was normal, and systemic examination revealed cervical lymphadenopathy and hepatosplenomegaly. The patient showed no improvement after 3 days of intravenous ceftriaxone, and a computed tomography scan showed a collection in the lacrimal sac. What would you do next?

Subconjunctival Mass 30 Years After Melanoma Resection

Abstract Full Text
has active quiz has multimedia
JAMA Ophthalmol. 2024;142(11):1089-1090. doi:10.1001/jamaophthalmol.2024.4289

A 70-year-old male is referred for evaluation of a conjunctival mass in the right eye, which has grown slowly over 27 years. Examination reveals a superonasal, multilobulated, pigmented lesion with episcleral feeder vessels and spontaneous vascular pulsations within the intraocular component. What would you do next?

Research Letter

Racial and Ethnic Disparities in Receipt of Retinal Imaging Among Patients With Diabetes

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1091-1094. doi:10.1001/jamaophthalmol.2024.4120

This cohort study examines racial and ethnic differences in varieties of advanced retinal imaging received among patients with diabetes at a single tertiary care institution.

Observation

Retinopathy Associated With Hair Dye

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1094-1096. doi:10.1001/jamaophthalmol.2024.3453

This case report describes a woman who presented with bilateral blurry vision a few days after dyeing her hair with hair dye containing aromatic amines.

Bilateral Acute Retinal Necrosis After Oncolytic HSV-1 Treatment of Glioblastoma

Abstract Full Text
JAMA Ophthalmol. 2024;142(11):1096-1098. doi:10.1001/jamaophthalmol.2024.3772

This case report discusses a case of bilateral acute retinal necrosis after administration of a recombinant oncolytic herpes simplex virus type 1 (HSV-1) in a 55-year-old patient with a grade IV glioblastoma.

Ophthalmic Images

Luxated Globe at Birth—A Vision-Threatening Emergency

Abstract Full Text
online only has active quiz
JAMA Ophthalmol. 2024;142(11):e243529. doi:10.1001/jamaophthalmol.2024.3529

This case report discusses a diagnosis of globe luxation at birth resulting from instrumental vaginal delivery.

Skin Discoloration After Iatrogenic Fluorescein Dosing Error

Abstract Full Text
online only has active quiz
JAMA Ophthalmol. 2024;142(11):e244285. doi:10.1001/jamaophthalmol.2024.4285

This case report describes a diagnosis of iatrogenic fluorescein dosing error in a girl aged 10 months who presented for routine fluorescein angiography examination in the setting of incontinentia pigmenti.

Retinopathy After Epiretinal Membrane Peeling

Abstract Full Text
online only has active quiz
JAMA Ophthalmol. 2024;142(11):e244290. doi:10.1001/jamaophthalmol.2024.4290

This case report describes a diagnosis of maculopathy associated with mechanical trauma from epiretinal membrane peeling in a man aged 84 years.

Correction

Error in Figures

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(11):1098. doi:10.1001/jamaophthalmol.2024.4610
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
free access
JAMA Ophthalmol. 2024;142(11):992. doi:10.1001/jamaophthalmol.2023.4606
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