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This Viewpoint addresses the high rate of incorrect ophthalmological diagnoses and harm experienced by patients and examines causes.

This cross-sectional study investigates how published polygenic risk scores for primary open-angle glaucoma (POAG) perform in groups with African ancestry compared with European ancestry.

This cohort study assesses the association between variability in blood pressure and visual field progression in patients with suspected or confirmed glaucoma.

A 20-year-old Chinese woman was experiencing fever, malaise, headache, nausea, vomiting, and neck stiffness for 2 weeks. Further examination revealed inflammation, vitritis and cystoid macular edema, tortuous dilatation of retinal venous vessels with fluorescence leakage, and hyperfluorescence in the optic disc. What would you do next?

This case report describes an HIV-positive patient with bilateral syphilitic panuveitis, for whom diagnosis was initially delayed by negative treponemal testing.

This post hoc analysis of a randomized clinical trial evaluates the use of a primary open-angle glaucoma polygenic risk score in identifying individuals with ocular hypertensive at low risk of disease onset.

This study investigates the genetic detection rates of wide-panel testing in Black and non-Hispanic White patients with IRDs.

A 46-year-old woman is referred for a second opinion with recent onset of suspected seizures and imbalance. Fundus examination revealed bilateral discrete perifoveal circular areas of atrophy. What would you do next?