January 1, 2023 Issue of JAMA Ophthalmology

January 2023, Vol 141, No. 1, Pages 8-104

Viewpoint

A Step Forward in Understanding Treatment Approaches for Diabetic Macular Edema

Jennifer K. Sun, MD, MPH; Carl W. Baker, MD; Lee M. Jampol, MD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):9-10. doi:10.1001/jamaophthalmol.2022.4666

This Viewpoint discusses new treatment approaches for diabetic macular edema.

Editorial

COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World

Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):11-12. doi:10.1001/jamaophthalmol.2022.5271

Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World

Editorial
COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski

JAMA
- Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World

Original Investigation

Associations of Alzheimer Disease鈥揚rotective APOE Variants With Age-Related Macular Degeneration

Katrine L. Rasmussen, MD, PhD; Anne Tybjærg-Hansen, MD, DMSc; Børge G. Nordestgaard, MD, DMSc; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):13-21. doi:10.1001/jamaophthalmol.2022.4602

This cohort study assesses genetic variations of APOE in association with risk of age-related macular degeneration.

Invited Commentary
Note the Nuance鈥擡xamining the Association of Alzheimer-Protective APOE Variation With Risk for Age-Related Macular Degeneration
Michelle Grunin, PhD; Tyler G. Kinzy, MS; Jessica N. Cooke Bailey, PhD, MA

JAMA Ophthalmol

Perceptions of Parental Leave Among Ophthalmologists

Kisha Kalra, BA; Thomas V. Delaney, PhD; Lora R. Dagi Glass, MD

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):24-31. doi:10.1001/jamaophthalmol.2022.5236

This survey study evaluates perceptions of current parental leave policy and culture among posttraining North American ophthalmologists.

Invited Commentary
Clock Is Still Ticking on Stop-the-Clock Policies
Julia A. Haller, MD

JAMA Ophthalmol

Association Between Rate of Ganglion Cell Complex Thinning and Rate of Central Visual Field Loss

Golnoush Mahmoudinezhad, MD, MPH; Sasan Moghimi, MD; Takashi Nishida, MD, PhD; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):33-39. doi:10.1001/jamaophthalmol.2022.4973

This cohort study analyzes whether the rate of macular ganglion cell complex thinning is associated with the rate of central visual field loss over time in adults with glaucoma.

Association of Treatment Type and Loss to Follow-up With Tractional Retinal Detachment in Proliferative Diabetic Retinopathy

Jonathan C. Tsui, MD; Yinxi Yu, MS; Brian L. VanderBeek, MD, MPH, MSCE

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):40-46. doi:10.1001/jamaophthalmol.2022.4942

This case-control study investigates the association of tractional retinal detachment in proliferative diabetic retinopathy with intravitreal injections compared with other treatment regimens.

Podcast: Association of Treatment Type and Loss to Follow-up With Tractional Retinal Detachment in Proliferative Diabetic Retinopathy

Invited Commentary
Challenges in the Clinical Management of Proliferative Diabetic Retinopathy: Treatment Choice and Follow-up
Jennifer K. Sun, MD, MPH; Danni Liu, MSPH

JAMA Ophthalmol

Estimating the Length of the Preclinical Detectable Phase for Open-Angle Glaucoma

Johan Aspberg, MD; Anders Heijl, MD, PhD; Boel Bengtsson, PhD

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):48-54. doi:10.1001/jamaophthalmol.2022.5056

This cohort study estimates the mean preclinical detectable phase for open-angle glaucoma.

Invited Commentary
Screening for Primary Open-Angle Glaucoma
Alfred Sommer, MD, MHS

JAMA Ophthalmol

Longitudinal Use of Telehealth During the COVID-19 Pandemic and Utility of Asynchronous Testing for Subspecialty-Level Ophthalmic Care

Arman Mosenia, MD, MSE; Patrick Li, MD; Rick Seefeldt, MS; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):56-61. doi:10.1001/jamaophthalmol.2022.4984

This quality improvement study compares telehealth use during the COVID-19 pandemic across clinical specialties at a single institution and assesses the feasibility of asynchronous testing with teleophthalmology.

Invited Commentary
Is There a Future for Telehealth in Ophthalmology?
David B. Glasser, MD

JAMA Ophthalmol

Inequities and Research Gaps in Ophthalmology: A Scoping Review

Christian Hemmerich, BS; Garrett Jones, BS; Jordan Staggs, BS; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):63-70. doi:10.1001/jamaophthalmol.2022.5237

This scoping review examines patient inequities that have been assessed from 2016 to 2021 within the field of ophthalmology.

Invited Commentary
From Research to Action鈥擨mplementing Initiatives to Address Ophthalmologic Health Disparities
Janice C. Law, MD; Michael A. Puente, MD

JAMA Ophthalmol

Brief Report

Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma

Owen M. Siggs, MD, DPhil; Ayub Qassim, MBBS, PhD; Xikun Han, PhD; et al.

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):73-77. doi:10.1001/jamaophthalmol.2022.4688

This cohort study investigates the association of polygenic risk with visual field progression in early glaucoma.

Invited Commentary

Note the Nuance鈥擡xamining the Association of Alzheimer-Protective APOE Variation With Risk for Age-Related Macular Degeneration

Michelle Grunin, PhD; Tyler G. Kinzy, MS; Jessica N. Cooke Bailey, PhD, MA

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):22-23. doi:10.1001/jamaophthalmol.2022.4600

Clock Is Still Ticking on Stop-the-Clock Policies

Julia A. Haller, MD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):31-32. doi:10.1001/jamaophthalmol.2022.5239

Challenges in the Clinical Management of Proliferative Diabetic Retinopathy: Treatment Choice and Follow-up

Jennifer K. Sun, MD, MPH; Danni Liu, MSPH

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):46-47. doi:10.1001/jamaophthalmol.2022.5057

Screening for Primary Open-Angle Glaucoma

Alfred Sommer, MD, MHS

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):55. doi:10.1001/jamaophthalmol.2022.5058

Is There a Future for Telehealth in Ophthalmology?

David B. Glasser, MD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):61-62. doi:10.1001/jamaophthalmol.2022.5130

From Research to Action鈥擨mplementing Initiatives to Address Ophthalmologic Health Disparities

Janice C. Law, MD; Michael A. Puente, MD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):71-72. doi:10.1001/jamaophthalmol.2022.5238

An Eye on Clinical Translation鈥擟onsiderations for Research Into Ocular Biomarkers of Alzheimer Disease and Related Dementias

Ashleigh Barrett-Young, PhD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):91-92. doi:10.1001/jamaophthalmol.2022.4959

Special Communication

Monkeypox Virus and Ophthalmology鈥擜 Primer on the 2022 Monkeypox Outbreak and Monkeypox-Related Ophthalmic Disease

Aaron R. Kaufman, MD; James Chodosh, MD, MPH; Roberto Pineda II, MD

Abstract Full Text

free access has active quiz

JAMA Ophthalmol. 2023;141(1):78-83. doi:10.1001/jamaophthalmol.2022.4567

This Special Communication reviews clinical information for the ophthalmologist regarding the ophthalmic manifestations of monkeypox virus and the 2022 disease outbreak.

Review

Ocular Biomarkers for Alzheimer Disease Dementia: An Umbrella Review of Systematic Reviews and Meta-analyses

Eliana Costanzo, MD; Imre Lengyel, PhD; Mariacristina Parravano, MD; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):84-91. doi:10.1001/jamaophthalmol.2022.4845

This umbrella review assesses the diagnostic accuracy of ocular biomarkers for early diagnosis of Alzheimer disease.

Invited Commentary
An Eye on Clinical Translation鈥擟onsiderations for Research Into Ocular Biomarkers of Alzheimer Disease and Related Dementias
Ashleigh Barrett-Young, PhD

JAMA Ophthalmol

JAMA Ophthalmology Clinical Challenge

A Case of Unilateral Intraocular Pressure Elevation in a Patient With Glaucoma

Katia E. Chavez, MD, MPH; Elizabeth A. Cretara, MD; Rachel E. Davis, MD

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):93-94. doi:10.1001/jamaophthalmol.2022.4735

A 52-year-old man with a history of severe primary open-angle glaucoma in both eyes presented with an intraocular pressure above target in the left eye. A 24-2 Humphrey visual field showed new glaucoma progression. What would you do next?

Acute Unilateral Proptosis After Blunt Orbital Trauma in an Adolescent Patient

Anthony P. Mai, MD; Edward P. Quigley III, MD, PhD; Roger P. Harrie, MD

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):95-96. doi:10.1001/jamaophthalmol.2022.4748

A male patient aged 16 years with a recent history of blunt trauma to the periorbita presented with blurred vision, pain, and proptosis of the right eye. MRI imaging revealed an intraconal mass. What would you do next?

Seeing Blue Dots After COVID-19 Infection

Haley S. D鈥橲ouza, MD; Prashant D. Tailor, MD; Timothy W. Olsen, MD

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):97-98. doi:10.1001/jamaophthalmol.2022.5235

A 12-year-old female individual receives a diagnosis of SARS-CoV-2 and reports bilateral blurry vision, large blue paracentral scotomata, and a migraine without a scintillating scotoma. What would you do next?

Research Letter

Hemorrhagic Occlusive Retinal Vasculitis Associated With Triamcinolone-Moxifloxacin Use During Uncomplicated Cataract Surgery

Warren W. Pan, MD, PhD; Andrew R. Miller, MD; Benjamin K. Young, MD, MS; et al.

Abstract Full Text

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JAMA Ophthalmol. 2023;141(1):99-101. doi:10.1001/jamaophthalmol.2022.4697

This case series describes the outcomes of cataract extraction with intraocular lens placement in 2 patients.

Observation

Acquired Nonpigmented Vitreous Cyst Associated With Regressed Diabetic Neovascularization

Diego Garcia-Davidson; George J. Wyhinny, MD; Enrique G. Valenzuela, MD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):101-102. doi:10.1001/jamaophthalmol.2022.5034

This case report describes a 48-year-old man with acquired nonpigmented vitreous cyst associated with regressed diabetic neovascularization.

Retinal Neovascularization in Posterior Polar Annular Choroidal Dystrophy

Nikhil Bommakanti, MD; Cagri G. Besirli, MD, PhD; Peter Y. Zhao, MD

Abstract Full Text

JAMA Ophthalmol. 2023;141(1):102-104. doi:10.1001/jamaophthalmol.2022.5269

This case report describes the development of posterior subcapsular cataract and retinal neovascularization in a patient with posterior polar annular choroidal dystrophy.

Ophthalmic Images

Congenital Common Canalicular Lacrimal Fistula in an Asymptomatic Patient

Yogita Gupta, MD, DNB, MRCSEd; Mandeep S. Bajaj, MD

Abstract Full Text

online only has active quiz

JAMA Ophthalmol. 2023;141(1):e224943. doi:10.1001/jamaophthalmol.2022.4943

This case report discusses a diagnosis of congenital common canalicular lacrimal fistula in a 24-year-old asymptomatic patient.

Bilateral Tapetal Reflex in a 12-Year-Old Girl

Sashwanthi Mohan, MBBS, DNB; Shruthi Suresh, MS

Abstract Full Text

online only has active quiz

JAMA Ophthalmol. 2023;141(1):e225106. doi:10.1001/jamaophthalmol.2022.5106

This case report describes a diagnosis of Oguchi disease in a girl aged 12 years with a history of high myopia and golden-metallic tapetal sheen noted on bilateral retinal examination.

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