Clinical Trial
Ygal Rotenstreich, MD; Michael Belkin, MD; Siegal Sadetzki, MD; et al.
free access
JAMA Ophthalmol. 2013;131(8):985-992. doi:10.1001/jamaophthalmol.2013.147
Rotenstreich et al determined the effect of oral treatment with 9-cis 尾-carotene on visual function of patients with retinitis pigmentosa. See also the by Pennesi.
Clinical Sciences
Carol L. Shields, MD; Swathi Kaliki, MD; Michael Livesey, BS; et al.
free access
JAMA Ophthalmol. 2013;131(8):993-1003. doi:10.1001/jamaophthalmol.2013.129
Shields and colleagues conducted a retrospective chart review of 7872 patients to determine the relationship of ocular/oculodermal (oculo[dermal]) melanocytosis to the prognosis of patients with uveal melanoma.
Clinical Sciences
Daniel L. Albertus, MD; Ira H. Schachar, MD, MSc; Sarwar Zahid, MD, MS; et al.
free access
JAMA Ophthalmol. 2013;131(8):1004-1008. doi:10.1001/jamaophthalmol.2013.4007
Albertus et al assess the utility of autofluorescence quantification in distinguishing clinically diagnosed choroidal nevi, melanoma, and indeterminate nevomelanocytic lesions. See related article by Schachar et al.
Clinical Sciences
Ira H. Schachar, MD, MSc; Sarwar Zahid, MD, MS; Grant M. Comer, MD, MS; et al.
free access
JAMA Ophthalmol. 2013;131(8):1009-1015. doi:10.1001/jamaophthalmol.2013.4014
Schachar et al develop a method for quantitative fundus autofluorescence image analysis that is capable of stratifying severity of nonexudative age-related macular degeneration. See related article by Albertus et al.
Clinical Sciences
Sarwar Zahid, MD, MS; Naheed Khan, PhD; Kari Branham, MS; et al.
free access
JAMA Ophthalmol. 2013;131(8):1016-1025. doi:10.1001/jamaophthalmol.2013.120
Zahid and colleagues conducted a retrospective medical record review to evaluate the clinical findings from patients with X-linked retinitis pigmentosa (XLRP) with 13 distinct RPGR mutations and assess for phenotypic concordance or variability.
Journal Club
Nina J. Hewing, MD; David R. Kaufman, PhD; R. V. Paul Chan, MD; et al.
free access
JAMA Ophthalmol. 2013;131(8):1026-1032. doi:10.1001/jamaophthalmol.2013.135
Hewing et al examine the diagnostic reasoning process of experts for plus disease in retinopathy of prematurity using qualitative research techniques.
Clinical Sciences
Susan B. Bressler, MD; Haijing Qin, MS; Michele Melia, ScM; et al.
free access
JAMA Ophthalmol. 2013;131(8):1033-1040. doi:10.1001/jamaophthalmol.2013.4154
Bressler et al perform an exploratory analysis to evaluate the effects of intravitreal ranibizumab or triamcinolone acetonide, administered to treat diabetic macular edema, on worsening of diabetic retinopathy.
Clinical Sciences
Klio I. Chatzistefanou, MD; Ioannis D. Ladas, MD; Konstantinos D. Droutsas, MD; et al.
free access
JAMA Ophthalmol. 2013;131(8):1041-1048. doi:10.1001/jamaophthalmol.2013.704
In a retrospective analysis, Chatzistefanou and coauthors outline the short- and long-term motor outcomes of graded bilateral medial rectus muscle recession and one lateral rectus muscle resection for the correction of large-angle esotropia (鈮�50 prism diopters).
Epidemiology
Jeffrey R. Willis, MD, PhD; Susan E. Vitale, PhD, MHS; Yuri Agrawal, MD; et al.
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JAMA Ophthalmol. 2013;131(8):1049-1056. doi:10.1001/jamaophthalmol.2013.316
To compare balance measures in individuals with normal vision, visual impairment, and uncorrected refractive error, Willis et al performed a cross-sectional study of 4590 adults, 40 years or older, participating in the 2001-2004 NHANES. Participants completed tests of standing balance with eyes open or eyes closed on a firm or compliant surface.
Ophthalmic Molecular Genetics
Hanan H. Afifi, MD, PhD; Amira A. Abdel Azeem, MD; Hala T. El-Bassyouni, MD, PhD; et al.
free access
JAMA Ophthalmol. 2013;131(8):1057-1066. doi:10.1001/jamaophthalmol.2013.644
Afifi and colleagues defined the ocular manifestations of Down syndrome in infants and children in Cairo, Egypt, a historically isolated region, and compared them with systemic features and with findings in other geographic groups.