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October 2024 - January 1929

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June 2013, Vol 131, No. 6, Pages 715-821

Viewpoint

Translational Science With Clinical Promise

Apical Scotomata, Confusion, and Diplopia

Marco A. Zarbin, MD, PhD
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):790. doi:10.1001/jamaophthalmol.2013.4640
Editorial

The Standardization of Uveitis Nomenclature Project: The Future Is Here

Annabelle A. Okada, MD; Douglas A. Jabs, MD, MBA
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):787-789. doi:10.1001/jamaophthalmol.2013.1596

Goodbye From the Editor

Daniel M. Albert, MD, MS
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):787. doi:10.1001/jamaophthalmol.2013.4982
Surgical Technique

Surgeon's Corner

Endovascular Cannulation With a Microneedle for Central Retinal Vein Occlusion

Kazuaki Kadonosono, MD; Shin Yamane, MD; Akira Arakawa, MD; et al.
Abstract Full Text
free access has multimedia
JAMA Ophthalmol. 2013;131(6):783-786. doi:10.1001/jamaophthalmol.2013.2585

Kadonosono et al developed a new surgical treatment in which a microneedle is used for retinal endovascular cannulation to treat eyes with central retinal vein occlusion by flushing thrombus out of the central retinal vein as it passes through the lamina cribrosa. The eyes of 12 consecutive patients were successfully treated using this technique.

  • Video: Retinal Endovascular Surgery
JAMA Ophthalmology Clinical Challenge

Conjunctivitis, Fever, and Tender Skin Nodules鈥擰uiz Case

Sotiria Palioura, MD, PhD; Adriano Piris, MD; James Chodosh, MD, MPH
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):791. doi:10.1001/jamaophthalmol.2013.4495a

Conjunctivitis, Fever, and Tender Skin Nodules鈥擠iagnosis

Abstract Full Text
JAMA Ophthalmol. 2013;131(6):792-793. doi:10.1001/jamaophthalmol.2013.4495b
Ophthalmic Images

Rhizopus Keratitis Following Corneal Trauma

Amir A. Azari, MD; Sarah Nehls, MD; Shahed Y. Ghoghawala, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):776. doi:10.1001/2013.jamaophthalmol.380

Krupin Valve Functioning as Culture Plate

Tabassum Ali, MD; Christine Callahan, MD
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):800. doi:10.1001/jamaophthalmol.2013.1053
Clinical Trials

Topical Interleukin 1 Receptor Antagonist for Treatment of Dry Eye Disease: A Randomized Clinical Trial

Francisco Amparo, MD, MSc; Mohammad H. Dastjerdi, MD; Andre Okanobo, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):715-723. doi:10.1001/jamaophthalmol.2013.195

Amparo et al performed a 16-week randomized clinical trial to evaluate the efficacy of treatment with the topical interleukin 1 (IL-1) receptor antagonist anakinra in patients having dry eye disease related to meibomian gland dysfunction.

Three-Month Randomized Trial of Fixed-Combination Brinzolamide, 1%, and Brimonidine, 0.2%

Gregory Katz, MD; Harvey DuBiner, MD; John Samples, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):724-730. doi:10.1001/jamaophthalmol.2013.188

In a phase 3 trial, Katz et al evaluated the efficacy and safety of fixed-combination brinzolamide, 1%, and brimonidine, 0.2%, compared with those of each component administered separately in 660 patients with open-angle glaucoma or ocular hypertension.

Clinical Sciences

Cultivated Limbal Epithelial Transplantation in Children With Ocular Surface Burns

Kunjal Sejpal, FRCS; Mohammed Hasnat Ali, MBA; Savitri Maddileti, MSc; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):731-736. doi:10.1001/jamaophthalmol.2013.2308

Sejpal and coauthors report the outcomes of autologous ex vivo cultivated limbal epithelial transplantation in pediatric patients undergoing limbal stem cell deficiency after ocular burns.

Journal Club

Effects of Graft Thickness and Asymmetry on Visual Gain and Aberrations After Descemet Stripping Automated Endothelial Keratoplasty

Mor M. Dickman, MD; Yanny Y. Y. Cheng, MD; Tos T. J. M. Berendschot, PhD; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):737-744. doi:10.1001/jamaophthalmol.2013.73

Autologous Fibrin Membrane Combined With Solid Platelet-Rich Plasma in the Management of Perforated Corneal Ulcers: A Pilot Study

Jorge L. Alio, PhD; Alejandra E. Rodriguez, MSc; Lorena M. Martinez, MD; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):745-751. doi:10.1001/jamaophthalmol.2013.2474

Alio et al evaluate use of autologous solid platelet-rich plasma in combination with an autologous fibrin membrane placed over the corneal surface as a temporary intervention in 11 patients with corneal perforation.

Mycobacterial Ocular Inflammation: Delay in Diagnosis and Other Factors Impacting Morbidity

Sarju S. Patel, MD, MPH, MSc; Nehali V. Saraiya, MD; Howard H. Tessler, MD; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):752-758. doi:10.1001/jamaophthalmol.2013.71

Patel et al describe presentations and outcomes of mycobacterial ocular disease in the Midwestern United States.

The Optokinetic Uncover Test: A New Insight Into Infantile Esotropia

Michael C. Brodsky, MD; Lindsay Klaehn, COT
Abstract Full Text
free access has multimedia
JAMA Ophthalmol. 2013;131(6):759-765. doi:10.1001/jamaophthalmol.2013.2348

To ascertain whether subcortical visual input contributes to the asymmetrical monocular optokinetic responses that characterize infantile esotropia, Brodsky and Klaehn performed the optokinetic uncover test in 7 patients with isolated infantile esotropia and in 3 patients with infantile esotropia syndrome associated with mild neurological disease.

  • Video: Optokinetic Uncover Test in Infantile Esotropia
Laboratory Sciences

Transcription, Translation, and Function of Lubricin, a Boundary Lubricant, at the Ocular Surface

Tannin A. Schmidt, PhD; David A. Sullivan, PhD; Erich Knop, MD, PhD; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):766-776. doi:10.1001/jamaophthalmol.2013.2385

Schmidt et al test the hypotheses that lubricin is produced by ocular surface epithelia and acts to protect the cornea and conjunctiva against significant shear forces generated during an eyelid blink and that lubricin deficiency increases shear stress on the ocular surface and promotes corneal damage.

Ophthalmic Molecular Genetics

Temporal Macular Thinning Associated With X-Linked Alport Syndrome

Faisal Ahmed, MD; Kandon K. Kamae, MD; Denise J. Jones, BS; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):777-782. doi:10.1001/jamaophthalmol.2013.1452

Ahmed et al correlate optical coherence tomography findings and severity of temporal macular thinning with COL4A5 mutations in a cohort with X-linked Alport syndrome.

Small Case Series

Novel Mutation in BEST1 Associated With Retinoschisis

Ruwan A. Silva, MD; Audina M. Berrocal, MD; Byron L. Lam, MD; et al.
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):794-798. doi:10.1001/jamaophthalmol.2013.2047

Congenital Bilateral Aplasia of Medial Recti in a Family

Anirudh Singh, MS; Anudeepa Sharma, MBBS; Pradeep Sharma, MD, FAMS
Abstract Full Text
free access
JAMA Ophthalmol. 2013;131(6):798-800. doi:10.1001/jamaophthalmol.2013.2889
Letters

Blue Toe Syndrome as a Complication of Intra-arterial Chemotherapy for Retinoblastoma

Ahmet Sarici, MD; Osman Kizilkilic, MD; Tiraje Celkan, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):801-802. doi:10.1001/jamaophthalmol.2013.1458

Fingolimod-Associated Macular Edema: Resolution by Sub-Tenon Injection of Triamcinolone With Continued Fingolimod Use

Ashley Minuk, BSc; Michel J. Belliveau, MD; David R. P. Almeida, MD, PhD, MBA; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):802-804. doi:10.1001/jamaophthalmol.2013.2465

Coding Variants in ARMS2 and the Risk of Age-Related Macular Degeneration

Gaofeng Wang, PhD; William K. Scott, PhD; Anita Agarwal, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):804-805. doi:10.1001/jamaophthalmol.2013.589

De Novo Splice Mutation in the Versican Gene in a Family With Wagner Syndrome

Pierre-Raphaël Rothschild, MD; Isabelle Audo, MD, PhD; Brigitte Nedelec; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):805-807. doi:10.1001/jamaophthalmol.2013.681

Interval Spectral-Domain Optical Coherence Tomography and Electrophysiology Findings in Neonatal Adrenoleukodystrophy

Robert J. Courtney, MD; Mark E. Pennesi, MD, PhD
Abstract Full Text
has multimedia
JAMA Ophthalmol. 2013;131(6):807-810. doi:10.1001/jamaophthalmol.2013.2089
  • Video: Spectral-Domain Optical Coherence Tomography

Mutation of GNAQ in a Cytologically Unusual Choroidal Melanoma in an 18-Month-Old Child

Steve Daniel Levasseur, MD; Katherine E. Paton, MD, FRCSC; Catherine D. Van Raamsdonk, BSc, MA, PhD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):810-812. doi:10.1001/jamaophthalmol.2013.2483

Mutational Analysis of GNAQ and GNA11 to Aid Therapy Management of a Choroidal Melanoma Metastatic to the Contralateral Orbit

Michael R. R. Böhm, MD; Athanasios Tsianakas, MD; Ralph-Laurent Merté, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):812-814. doi:10.1001/jamaophthalmol.2013.1921

Histopathologic, Immunohistochemical, and Cytogenetic Analysis of Primary Clear Cell Melanoma of the Uvea

Robert M. Verdijk, MD, PhD; Anna E. Koopmans, MD; Emine Kilic, MD, PhD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):814-816. doi:10.1001/jamaophthalmol.2013.1939

Lichen Simplex Chronicus of the Conjunctiva

Heather D. Potter, MD; Vivian Lee, MD; Molly A. Hinshaw, MD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):816-818. doi:10.1001/jamaophthalmol.2013.1890

Decreased Surface Temperature of Tarsal Conjunctiva in Patients With Meibomian Gland Dysfunction

Reiko Arita, MD, PhD; Rika Shirakawa, MD; Shuji Maeda, MD, PhD; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):818-819. doi:10.1001/jamaophthalmol.2013.1895

Central Visual Field Loss and Driving鈥擱eply

P. Matthew Bronstad, PhD; Alex R. Bowers, PhD; Amanda Albu, BA; et al.
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):819-821. doi:10.1001/jamaophthalmol.2013.4259

Central Visual Field Loss and Driving

Ediriweera Desapriya, PhD; D. Sesath Hewapathirane, PhD; Ian Pike, PhD
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):819-821. doi:10.1001/jamaophthalmol.2013.434

On Capsule Membrane Fixation

Manuel S. Falcão, MD; Manuel Domingues, MD
Abstract Full Text
JAMA Ophthalmol. 2013;131(6):821. doi:10.1001/jamaophthalmol.2013.1484
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