Clinical Trial
The Age-Related Eye Disease Study 2 (AREDS2) Research Group; Emily Y. Chew, MD; John Paul SanGiovanni, ScD; et al.
free access
has audio
JAMA Ophthalmol. 2013;131(7):843-850. doi:10.1001/jamaophthalmol.2013.4412
The Age-Related Eye Disease Study 2 (AREDS2) Research Group conducted a multicenter, double-masked clinical trial to determine whether daily oral supplementation with lutein/zeaxanthin affects the risk for cataract surgery.
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Podcast:
Lutein/Zeaxanthin for the Treatment of Age-Related Cataract: AREDS2 Randomized Trial Report No. 4
Clinical Trial
Ivan J. Suñer, MD; Neil M. Bressler, MD; Rohit Varma, MD; et al.
free access
JAMA Ophthalmol. 2013;131(7):851-856. doi:10.1001/jamaophthalmol.2013.114
Suñer et al examined the benefit of ranibizumab (Lucentis) on measured reading speed, a direct performance assessment, through 6 months in eyes of patients with macular edema after retinal vein occlusion.
Clinical Sciences
Carol L. Shields, MD; Audrey C. Regillo; Phoebe L. Mellen, BS; et al.
free access
JAMA Ophthalmol. 2013;131(7):857-863. doi:10.1001/jamaophthalmol.2013.160
C. L. Shields and colleagues conducted a retrospective case series of 618 patients with conjunctival nevus, 32 of which had giant conjunctival nevus, to describe the clinical features and outcomes of giant (≥10 mm diameter) conjunctival nevus.
Clinical Sciences
Alan T. Sheyman, MD; Ben Z. Cohen, MD; Alan H. Friedman, MD; et al.
free access
JAMA Ophthalmol. 2013;131(7):864-869. doi:10.1001/jamaophthalmol.2013.88
Sheyman et al report an outbreak of fungal endophthalmitis in a series of patients following intravitreal injection of combined bevacizumab and triamcinolone prepared by the same compounding pharmacy.
Journal Club
Diabetic Retinopathy Clinical Research Network Authors/Writing Committee; Carl W. Baker, MD; Talat Almukhtar, MBChB; et al.
free access
JAMA Ophthalmol. 2013;131(7):870-879. doi:10.1001/jamaophthalmol.2013.2313
Baker et al estimate the incidence of central-involved macular edema 16 weeks following cataract surgery in eyes with diabetic retinopathy without definite central-involved diabetic macular edema preoperatively.
Clinical Sciences
Seong Joon Ahn, MD; Jeeyun Ahn, MD; Kyu Hyung Park, MD; et al.
free access
JAMA Ophthalmol. 2013;131(7):880-890. doi:10.1001/jamaophthalmol.2013.172
To investigate the clinical and retinal pathologic features of occult macular dystrophy, Ahn et al studied 46 eyes from 25 Korean patients using various imaging modalities. Quantitative and qualitative morphologic features were evaluated for their association with visual and electrophysiologic function.
Clinical Sciences
Daniel B. Moore, MD; Mark A. Slabaugh, MD
free access
JAMA Ophthalmol. 2013;131(7):891-897. doi:10.1001/jamaophthalmol.2013.202
Moore and Slabaugh evaluate the visual results and cost-effectiveness of surgical residents performing attending-supervised cataract surgery in a population of uninsured patients.
Clinical Sciences
Brian G. Mohney, MD; Ryan C. Young, MD; Nancy Diehl, BS
free access
JAMA Ophthalmol. 2013;131(7):898-902. doi:10.1001/jamaophthalmol.2013.65
Mohney et al determined the incidence of optic nerve hypoplasia and the rate of associated endocrine, neurologic, and developmental abnormalities among a population-based cohort of pediatric patients.
Laboratory Sciences
Brian C. Tse, MD; Jena J. Steinle, PhD; Dianna Johnson, PhD; et al.
free access
JAMA Ophthalmol. 2013;131(7):903-911. doi:10.1001/jamaophthalmol.2013.2065
Tse et al used comprehensive ocular and orbital histopathology to further document previously reported toxic effects observed with real-time ophthalmoscopy during superselective intraophthalmic artery chemotherapy in a nonhuman primate model.
Socioeconomics and Health Services
Heather E. Whitson, MD, MHS; Diane Whitaker, OD; Guy Potter, PhD; et al.
free access
JAMA Ophthalmol. 2013;131(7):912-919. doi:10.1001/jamaophthalmol.2013.1700
Whitson and coauthors describe a low-vision rehabilitation program for patients with macular disease and cognitive deficits.