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July 2013, Vol 131, No. 7, Pages 827-970

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):827. doi:10.1001/jamaophthalmol.2013.4121
Viewpoint

Translational Science With Clinical Promise

Personalized Medicine: Bayesian Inference as Applied to the Measurement of Glaucomatous Visual Field Loss

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):837-838. doi:10.1001/jamaophthalmol.2013.5145
Editorial

JAMA Ophthalmology: It’s Not Just a New Name

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):839. doi:10.1001/jamaophthalmol.2013.5420

Is the Use of Topical Antibiotics for Intravitreal Injections the Standard of Care or Are We Better Off Without Antibiotics?

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):840-842. doi:10.1001/jamaophthalmol.2013.2524
Original Investigation

Clinical Trial

Lutein/Zeaxanthin for the Treatment of Age-Related Cataract: AREDS2 Randomized Trial Report No. 4

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JAMA Ophthalmol. 2013;131(7):843-850. doi:10.1001/jamaophthalmol.2013.4412

The Age-Related Eye Disease Study 2 (AREDS2) Research Group conducted a multicenter, double-masked clinical trial to determine whether daily oral supplementation with lutein/zeaxanthin affects the risk for cataract surgery.

Clinical Trial

Reading Speed Improvements in Retinal Vein Occlusion After Ranibizumab Treatment

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):851-856. doi:10.1001/jamaophthalmol.2013.114

Suñer et al examined the benefit of ranibizumab (Lucentis) on measured reading speed, a direct performance assessment, through 6 months in eyes of patients with macular edema after retinal vein occlusion.

Clinical Sciences

Giant Conjunctival Nevus: Clinical Features and Natural Course in 32 Cases

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):857-863. doi:10.1001/jamaophthalmol.2013.160

C. L. Shields and colleagues conducted a retrospective case series of 618 patients with conjunctival nevus, 32 of which had giant conjunctival nevus, to describe the clinical features and outcomes of giant (≥10 mm diameter) conjunctival nevus.

Clinical Sciences

An Outbreak of Fungal Endophthalmitis After Intravitreal Injection of Compounded Combined Bevacizumab and Triamcinolone

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):864-869. doi:10.1001/jamaophthalmol.2013.88

Sheyman et al report an outbreak of fungal endophthalmitis in a series of patients following intravitreal injection of combined bevacizumab and triamcinolone prepared by the same compounding pharmacy.

Journal Club

Macular Edema After Cataract Surgery in Eyes Without Preoperative Central-Involved Diabetic Macular Edema

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):870-879. doi:10.1001/jamaophthalmol.2013.2313

Baker et al estimate the incidence of central-involved macular edema 16 weeks following cataract surgery in eyes with diabetic retinopathy without definite central-involved diabetic macular edema preoperatively.

Clinical Sciences

Multimodal Imaging of Occult Macular Dystrophy

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):880-890. doi:10.1001/jamaophthalmol.2013.172

To investigate the clinical and retinal pathologic features of occult macular dystrophy, Ahn et al studied 46 eyes from 25 Korean patients using various imaging modalities. Quantitative and qualitative morphologic features were evaluated for their association with visual and electrophysiologic function.

Clinical Sciences

Surgical Outcomes and Cost Basis for Resident-Performed Cataract Surgery in an Uninsured Patient Population

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JAMA Ophthalmol. 2013;131(7):891-897. doi:10.1001/jamaophthalmol.2013.202

Moore and Slabaugh evaluate the visual results and cost-effectiveness of surgical residents performing attending-supervised cataract surgery in a population of uninsured patients.

Clinical Sciences

Incidence and Associated Endocrine and Neurologic Abnormalities of Optic Nerve Hypoplasia

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):898-902. doi:10.1001/jamaophthalmol.2013.65

Mohney et al determined the incidence of optic nerve hypoplasia and the rate of associated endocrine, neurologic, and developmental abnormalities among a population-based cohort of pediatric patients.

Laboratory Sciences

Superselective Intraophthalmic Artery Chemotherapy in a Nonhuman Primate Model: Histopathologic Findings

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):903-911. doi:10.1001/jamaophthalmol.2013.2065

Tse et al used comprehensive ocular and orbital histopathology to further document previously reported toxic effects observed with real-time ophthalmoscopy during superselective intraophthalmic artery chemotherapy in a nonhuman primate model.

Socioeconomics and Health Services

A Low-Vision Rehabilitation Program for Patients With Mild Cognitive Deficits

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):912-919. doi:10.1001/jamaophthalmol.2013.1700

Whitson and coauthors describe a low-vision rehabilitation program for patients with macular disease and cognitive deficits.

Case Report/Case Series

Immunological Rejection Following Allogeneic Cultivated Limbal Epithelial Transplantation

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):920-922. doi:10.1001/jamaophthalmol.2013.15

Intravitreal Fasudil Combined With Bevacizumab for Persistent Diabetic Macular Edema: A Novel Treatment

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):923-924. doi:10.1001/jamaophthalmol.2013.143

Inadvertent Implantation of Aqueous Tube Shunts in Glaucomatous Eyes With Unrecognized Intraocular Neoplasms: Report of 5 Cases

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):925-928. doi:10.1001/jamaophthalmol.2013.828

Dacryops: A Series of 5 Cases and a Proposed Pathogenesis

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):929-932. doi:10.1001/jamaophthalmol.2013.1885

Lam and colleagues reported 5 cases of lacrimal gland ductal cysts (dacryops) identified at the Ottawa Hospital over a 3-year period (2009-2012) to determine their pathogenesis.

Special Communication

Jacques Guillemeau’s 16th-Century Account of Ophthalmoplegia

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):933-936. doi:10.1001/jamaophthalmol.2013.596

Domínguez-Rodríguez and González-Hernández describe French royal surgeon Jacques Guillemeau’s theoretical framework and practical approach to a form of ophthalmoplegia involving progressive paralysis of extraocular muscles.

The Blinding of the Lawgiver Zaleukos on a 16th-Century German Medal

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):937-940. doi:10.1001/2013.jamaophthalmol.324
Surgical Technique

Surgeon's Corner

A Novel Technique of Modified Continuous Blanket Suture for Amniotic Membrane Fixation in Severe Ocular Surface Diseases

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):941-947. doi:10.1001/jamaophthalmol.2013.2125

Zhang and colleagues demonstrated a novel technique using modified continuous blanket suture to fix the amniotic membrane in different severe ocular surface disease lesions.

From the ÌÇÐÄvlog

Is the Prevalence of Visual Impairment Rising or Falling in the People With Diabetes Mellitus?It Depends on Who You Study

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):948-950. doi:10.1001/jamaophthalmol.2013.4023
JAMA Ophthalmology Clinical Challenge

Anterior Chamber Angiostrongyliasis

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):951-952. doi:10.1001/jamaophthalmol.2013.4620
Research Letter

Oral Glucosamine Supplements as a Possible Ocular Hypertensive Agent

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):955-957. doi:10.1001/jamaophthalmol.2013.227

Progression of Diabetic Retinopathy in the Hypertension Intervention Nurse Telemedicine Study

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):957-958. doi:10.1001/jamaophthalmol.2013.81

Long-term Suppression of Multidrug-Resistant Cytomegalovirus Retinitis With Systemically Administered Leflunomide

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):958-960. doi:10.1001/jamaophthalmol.2013.1589

Sclerochoroidal Calcification Is Primarily a Scleral Condition Based on Enhanced Depth Imaging Optical Coherence Tomography

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):960-963. doi:10.1001/jamaophthalmol.2013.67

Retinal Vascular Precipitates During Administration of Melphalan Into the Ophthalmic Artery

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):963-965. doi:10.1001/jamaophthalmol.2013.1469

Prenatal Presentation of Fronto-orbital Congenital Infantile Fibrosarcoma: A Clinicopathologic Report

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):965-967. doi:10.1001/jamaophthalmol.2013.1934
Observation

Growth of Type 1 Neovascularization Following Cessation of Anti–Vascular Endothelial Growth Factor Therapy as a Possible Explanation for Treatment Resistance

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):967-969. doi:10.1001/jamaophthalmol.2013.2120

Varicella-Zoster Virus–Associated Multifocal Chorioretinitis in 2 Boys

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):969-970. doi:10.1001/jamaophthalmol.2013.167
Ophthalmic Images

Extensive Retinal Involvement of Metastatic Neuroblastoma

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):869. doi:10.1001/jamaophthalmol.2013.1074

Spontaneous Vitreous Hemorrhage in a Case of Retinal Cavernous Hemangioma: A Rare Presentation

Abstract Full Text
JAMA Ophthalmol. 2013;131(7):897. doi:10.1001/jamaophthalmol.2013.1424
JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2013;131(7):828. doi:10.1001/jamaophthalmol.2013.4119
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