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Adhi et al analyze the morphological features and vascular layers of the choroid in patients with diabetic retinopathy using spectral-domain optical coherence tomography.

Sarraf and coauthors characterize a new spectral domain optical coherence tomography presentation of acute macular neuroretinopathy as a paracentral acute middle maculopathy.

In a randomized double-masked phase 1 clinical trial, Tanihara et al studied the interocular pressure–lowering effects and safety of topical administration of a selective Rho kinase inhibitor, K-115, in healthy male adult volunteers. In the initial single-instillation trial and the repeated-instillation trial, 50 healthy volunteers were treated with placebo or K-115.

Liskova et al report 2 novel ZEB1 mutations identified in 2 Czech probands with posterior polymorphous corneal dystrophy 3 and provide a detailed phenotypic description.

Vehof et al demonstrate an association between reduced pain tolerance, as measured by a heat pain stimulus, and the presence of dry eye symptoms in a large sample of population-representative women.

Azuma et al evaluate visual outcomes in eyes with aggressive posterior retinopathy of prematurity after early vitreous surgery.

Dessalces et al examine a large series of patients with retinitis punctata albescens (RPA) to document disease progression and visual function.

Yzer et al expand the clinical spectrum of enhanced S-cone syndrome due to mutations in the NR2E3 gene.

Sakane et al develop and validate a questionnaire to evaluate the multifaceted effect of dry eye disease on patients’ daily life, including mental health.

Mitchell and colleagues examine the effect of intravitreal ranibizumab treatment compared with laser on patient-reported visual function.

Itakura and Kishi describe the role of the posterior precortical vitreous pocket in early-stage posterior vitreous detachments in healthy individuals.