Lars Skou Elkjær, MD; Bodil Hammer Bech, PhD; Yuelian Sun, PhD; et al.
free access
JAMA Neurol. 2018;75(6):663-671. doi:10.1001/jamaneurol.2017.5035
This population-based study evaluates the association between school performance and maternal use of valproate in children exposed prenatally.
Diego Z. Carvalho, MD; Erik K. St Louis, MD, MS; David S. Knopman, MD; et al.
free access
JAMA Neurol. 2018;75(6):672-680. doi:10.1001/jamaneurol.2018.0049
This cohort analysis assesses whether excessive daytime sleepiness at baseline is associated with longitudinal regional β-amyloid accumulation in elderly persons without dementia.
Rebecca K. Sheean, PhD; Fiona C. McKay, PhD; Erika Cretney, PhD; et al.
free access
JAMA Neurol. 2018;75(6):681-689. doi:10.1001/jamaneurol.2018.0035
This human and animal study assesses the role of regulatory T-cells in the pathophysiology of amyotrophic lateral sclerosis and the therapeutic association with increasing regulatory T-cell activity in a mouse model of the disease.
Sarah A. Morrow, MD, MS, FRCPC; J. Alexander Fraser, MD, FRCPC; Chad Day, BScH; et al.
free access
JAMA Neurol. 2018;75(6):690-696. doi:10.1001/jamaneurol.2018.0024
This randomized clinical trial assesses whether the administration of high-dose intravenous corticosteroid is superior to a bioequivalent oral corticosteroid dose for the treatment of patients with acute optic neuritis.
Christopher A. Abeare, PhD; Isabelle Messa, MSc; Brandon G. Zuccato, BA; et al.
free access
JAMA Neurol. 2018;75(6):697-703. doi:10.1001/jamaneurol.2018.0031
This cross-sectional study investigates the prevalence of invalid performance on baseline testing for athletes aged 10 to 21 years who completed neurocognitive testing for the management of sport-related concussion.
Benjamin K. Dawson, BSc; Seyed-Mohammad Fereshtehnejad, MD, MPH, PhD; Julius B. M. Anang, MD, PhD; et al.
free access
JAMA Neurol. 2018;75(6):704-710. doi:10.1001/jamaneurol.2018.0254
This cohort study presents an office-based screening tool for the risk of dementia in Parkinson disease.
Jing Jing, MD, PhD; Xia Meng, MD, PhD; Xingquan Zhao, MD, PhD; et al.
free access
JAMA Neurol. 2018;75(6):711-719. doi:10.1001/jamaneurol.2018.0247
This imaging substudy of a randomized clinical trial investigates whether infarction patterns can be used to stratify the risk of recurrent stroke within 3 months of a transient ischemic attack or minor ischemic stroke.
Iain D. Croall, PhD; Daniel J. Tozer, PhD; Barry Moynihan, MD; et al.
open access
JAMA Neurol. 2018;75(6):720-727. doi:10.1001/jamaneurol.2017.5153
This randomized clinical trial investigates whether standard vs intensive blood pressure lowering over 3 months causes decreased cerebral perfusion in small vessel disease.
Zachary A. Miller, MD; Lynne Rosenberg, BA; Miguel A. Santos-Santos, MD; et al.
free access
JAMA Neurol. 2018;75(6):728-737. doi:10.1001/jamaneurol.2018.0395
This case-control study investigates the prevalence and type of learning disability in a cohort of patients with posterior cortical atrophy compared with patients with logopenic variant primary progressive aphasia and amnestic Alzheimer disease.
Alberto Lleó, MD, PhD; David J. Irwin, MD; Ignacio Illán-Gala, MD; et al.
free access
JAMA Neurol. 2018;75(6):738-745. doi:10.1001/jamaneurol.2018.0118
This case-control study assesses the use of an algorithm based on core Alzheimer disease cerebrospinal fluid measures to exclude cases with AD pathology and then differentiate between frontotemporal lobar degeneration tau and frontotemporal lobar degeneration transactive response DNA-binding protein.