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October 2024 - July 1959

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April 2018, Vol 75, No. 4, Pages 391-518

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):391. doi:10.1001/jamaneurol.2017.2631
Viewpoint

Determining If Rest Is Best After Concussion

Abstract Full Text
JAMA Neurol. 2018;75(4):399-400. doi:10.1001/jamaneurol.2018.0006

This Viewpoint reports on the evidence determining whether rest is necessary after concussion.

On the Brain

Leaving Against Medical Advice

Abstract Full Text
JAMA Neurol. 2018;75(4):401. doi:10.1001/jamaneurol.2017.4896
Editorial

Time May Be of the Essence in the Treatment of Pediatric Patients With Refractory Convulsive Status Epilepticus

Abstract Full Text
JAMA Neurol. 2018;75(4):402-403. doi:10.1001/jamaneurol.2017.4028

Keeping Faith With Patients After Stroke or Transient Ischemic Attack

Abstract Full Text
JAMA Neurol. 2018;75(4):404-405. doi:10.1001/jamaneurol.2017.4027

Tissue Markers for Acute Multiple Sclerosis Treatment Response—A Step Toward Personalized Medicine

Abstract Full Text
JAMA Neurol. 2018;75(4):406-407. doi:10.1001/jamaneurol.2017.4850
Original Investigation

Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):410-418. doi:10.1001/jamaneurol.2017.4382

This cohort study examines the association between delay in initiation of first-line benzodiazepine treatment and short-term outcomes for children hospitalized with refractory convulsive status epilepticus.

Quality of Care for Veterans With Transient Ischemic Attack and Minor Stroke

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):419-427. doi:10.1001/jamaneurol.2017.4648

This cohort study assesses the quality of guideline-recommended transient ischemic attack and minor stroke care across the Veterans Health Administration system nationwide.

Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):428-435. doi:10.1001/jamaneurol.2017.4842

This cohort study evaluates the differences in response to apheresis treatment of patients with 3 histopathologically defined immunopathological patterns of multiple sclerosis.

Acute Brain Lesions on Magnetic Resonance Imaging and Delayed Neurological Sequelae in Carbon Monoxide Poisoning

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):436-443. doi:10.1001/jamaneurol.2017.4618

This study examines whether acute brain lesions on diffusion-weighted imaging are related to delayed neurological sequelae after carbon monoxide poisoning.

Efficacy of Oral Mixed Tocotrienols in Diabetic Peripheral Neuropathy: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):444-452. doi:10.1001/jamaneurol.2017.4609

This randomized clinical trial evaluates the efficacy of oral mixed tocotrienols for patients with diabetic peripheral neuropathy.

Association of Reperfusion With Brain Edema in Patients With Acute Ischemic Stroke: A Secondary Analysis of the MR CLEAN Trial

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):453-461. doi:10.1001/jamaneurol.2017.5162

This study examines the association between reperfusion and brain edema in patients with acute ischemic stroke.

Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):462-470. doi:10.1001/jamaneurol.2017.4365

This subgroup analysis of a randomized clinical trial examines whether the apolipoprotein E ε4 allele modifies the previously reported significant cognitive benefits of a multidomain lifestyle intervention.

Effect of General Anesthesia and Conscious Sedation During Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):470-477. doi:10.1001/jamaneurol.2017.4474

This randomized clinical trial analyzes the effect of general anesthesia and conscious sedation on infarct growth and clinical outcome of patients who underwent endovascular therapy for acute ischemic stroke.

Disease Course and Treatment Responses in Children With Relapsing Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):478-487. doi:10.1001/jamaneurol.2017.4601

This multinational cohort study examines the clinical phenotypes, treatment responses, and outcomes of children with relapsing myelin oligodendrocyte glycoprotein antibody–associated disease.

Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):488-494. doi:10.1001/jamaneurol.2017.4325

This longitudinal study examines the association of age, β-amyloid levels, and the apolipoprotein E ε4 allele with memory decline in a large group of cognitively healthy older adults enrolled in the Australian Imaging, Biomarkers, and Lifestyle study.

Clinical, Biomarker, and Molecular Delineations and Genotype-Phenotype Correlations of Ataxia With Oculomotor Apraxia Type 1

Abstract Full Text
free access has multimedia
JAMA Neurol. 2018;75(4):495-502. doi:10.1001/jamaneurol.2017.4373

This study defines the clinical, biomarker, and molecular spectrum and provides genotype-phenotype correlations among patients with ataxia with oculomotor apraxia type 1 from 18 countries.

Review

When Do α-Synucleinopathies Start? An Epidemiological Timeline: A Review

Abstract Full Text
has audio
JAMA Neurol. 2018;75(4):503-509. doi:10.1001/jamaneurol.2017.4243

This review evaluates the literature for the epidemiological evidence of features of α-synucleinopathies that occur before clinical onset of disease, proposes a clinical timeline of the features, and attempts to define the different premotor and clinical phenotypes associated with α-synucleinopathies.

Images in Neurology

Appearance of an Unusual Cerebellar Lesion

Abstract Full Text
JAMA Neurol. 2018;75(4):510-511. doi:10.1001/jamaneurol.2017.4726

This case report describes the presentation of Lhermitte-Duclos disease and its association with Cowden disease.

Mirror Movements in a Patient With Brain Tumor

Abstract Full Text
has multimedia
JAMA Neurol. 2018;75(4):512. doi:10.1001/jamaneurol.2017.4879

This case report describes a man in his late 40s with left-hand mirror movements.

Research Letter

Medical Specialties of Clinicians Providing Mechanical Thrombectomy to Patients With Acute Ischemic Stroke in the United States

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):515-517. doi:10.1001/jamaneurol.2017.5172

This cross-sectional analysis of Medicare data determined the specialty of physicians providing mechanical thrombectomy to patients with ischemic stroke.

Comment & Response

Considerations in Assessing Disability Trajectories Before and After Stroke and Myocardial Infarction

Abstract Full Text
JAMA Neurol. 2018;75(4):517. doi:10.1001/jamaneurol.2018.0196

Considerations in Assessing Disability Trajectories Before and After Stroke and Myocardial Infarction

Abstract Full Text
JAMA Neurol. 2018;75(4):517-518. doi:10.1001/jamaneurol.2018.0199

Considerations in Assessing Disability Trajectories Before and After Stroke and Myocardial Infarction—Reply

Abstract Full Text
JAMA Neurol. 2018;75(4):518. doi:10.1001/jamaneurol.2018.0202
Correction

Errors in Figure 1

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):518. doi:10.1001/jamaneurol.2018.0085

Missing Author Affiliation

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):518. doi:10.1001/jamaneurol.2018.0446
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2018;75(4):398. doi:10.1001/jamaneurol.2017.2632
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