Kassandra L. Munger, ScD; Julia Åivo, MD; Kira Hongell, MD; et al.
free access
JAMA Neurol. 2016;73(5):515-519. doi:10.1001/jamaneurol.2015.4800
This nested case-control study in the Finnish Maternity Cohort examines whether insufficient D levels in early pregnancy are associated with risk of multiple sclerosis in offspring.
Laura Negrotto, MD; Mauricio F. Farez, MD, MPH; Jorge Correale, MD
free access
JAMA Neurol. 2016;73(5):520-528. doi:10.1001/jamaneurol.2015.4807
This cohort study evaluates the effects of metformin and pioglitazone on immune regulation in patients with multiple sclerosis and metabolic syndrome and evaluates potential mechanisms underlying this anti-inflammatory effect.
Alexander Egeberg, MD, PhD; Peter Riis Hansen, MD, PhD, DMSci; Gunnar H. Gislason, MD, PhD; et al.
free access
JAMA Neurol. 2016;73(5):529-534. doi:10.1001/jamaneurol.2016.0022
This population-based study examines the association between rosacea and the subsequent development of Parkinson disease in Denmark.
Daniel Weintraub, MD; Claire Chiang, PhD; Hyungjin Myra Kim, ScD; et al.
free access
JAMA Neurol. 2016;73(5):535-541. doi:10.1001/jamaneurol.2016.0031
This matched-cohort study uses Veterans Health Administration data to assess whether use of antipsychotics in a population of veterans with Parkinson disease is associated with increased mortality.
Tonny V. Veenith, FRCA; Eleanor L. Carter, FRCA; Thomas Geeraerts, PhD; et al.
free access
JAMA Neurol. 2016;73(5):542-550. doi:10.1001/jamaneurol.2016.0091
This case-control study used fluorine 18鈥搇abeled fluoromisonidazole tracer and oxygen 15鈥搇abeled positron emission tomography to determine the pathophysiologic mechanisms of cerebral ischemia and diffusion hypoxia in patients with early traumatic brain injury.
Linda Papa, MDCM, MSc; Gretchen M. Brophy, PharmD; Robert D. Welch, MD, MS; et al.
free access
JAMA Neurol. 2016;73(5):551-560. doi:10.1001/jamaneurol.2016.0039
This cohort study evaluates the temporal profiles of GFAP and UCH-L1 in a large cohort of trauma patients and assesses their diagnostic accuracy over time for detecting traumatic brain injury, traumatic intracranial lesions on head computed tomography, and neurosurgical intervention.
Rawan Tarawneh, MD; Gina D鈥橝ngelo, PhD; Dan Crimmins, PhD; et al.
free access
JAMA Neurol. 2016;73(5):561-571. doi:10.1001/jamaneurol.2016.0086
This study investigates the diagnostic and prognostic utility of cerebrospinal fluid neurogranin levels in a large well-characterized cohort of individuals with symptomatic Alzheimer disease and cognitively normal controls.
Shadi Yaghi, MD; Sara K. Rostanski, MD; Amelia K. Boehme, PhD; et al.
free access
JAMA Neurol. 2016;73(5):572-578. doi:10.1001/jamaneurol.2015.4906
This cohort study seeks to determine predictors of early recurrent cerebrovascular events among patients with transient ischemic attacks and minor strokes and National Institutes of Health Stroke Scale scores of 0 to 3.
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Editorial
The Challenges of Stroke Prediction Scores
Deena M. Nasr, DO; Robert D. Brown Jr, MD, MPH
JAMA Neurol
Susanna M. Zuurbier, MD; Marcel Arnold, MD, PhD; Saskia Middeldorp, MD, PhD; et al.
free access
JAMA Neurol. 2016;73(5):579-584. doi:10.1001/jamaneurol.2016.0001
This case-control study assesses whether obesity is a risk factor for central venous thrombosis.
Sherri A. Braksick, MD; David B. Burkholder, MD; Spyridoula Tsetsou, MD; et al.
free access
JAMA Neurol. 2016;73(5):585-590. doi:10.1001/jamaneurol.2016.0006
This study evaluates the incidence of stimulus-induced rhythmic, periodic, or ictal discharges found in prolonged electroencephalographic recordings and their clinical implications in critically ill patients.