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October 2024 - July 1959

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April 2016, Vol 73, No. 4, Pages 369-483

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2016;73(4):369. doi:10.1001/jamaneurol.2015.2449
Viewpoint

Next Generation Neurology

The Human Alzheimer Disease Project: Answering the Call

Abstract Full Text
JAMA Neurol. 2016;73(4):373-374. doi:10.1001/jamaneurol.2015.4512

This Viewpoint outlines the roles and interactions of organizations conducting research leadsing to effective treatments for Alzheimer disease.

Editorial

The Prevention of Epilepsy

Abstract Full Text
JAMA Neurol. 2016;73(4):375-376. doi:10.1001/jamaneurol.2015.4780

Predicting Early Recurrent Stroke With the Recurrence Risk Estimator

Abstract Full Text
JAMA Neurol. 2016;73(4):376-378. doi:10.1001/jamaneurol.2015.5047

The Place of Neuroimaging in the Assessment of Cerebral Small Vessel Disease

Abstract Full Text
JAMA Neurol. 2016;73(4):378-379. doi:10.1001/jamaneurol.2015.4735

Do Proton Pump Inhibitors Increase the Risk of Dementia?

Abstract Full Text
JAMA Neurol. 2016;73(4):379-381. doi:10.1001/jamaneurol.2015.4931

New Findings in Adult Opsoclonus-Myoclonus Syndrome

Abstract Full Text
JAMA Neurol. 2016;73(4):381-382. doi:10.1001/jamaneurol.2015.4757

To Dement or Not to Dement, That Is the Question

Abstract Full Text
JAMA Neurol. 2016;73(4):383-384. doi:10.1001/jamaneurol.2015.4984

Cognitive Decline in Presymptomatic Alzheimer Disease

Abstract Full Text
JAMA Neurol. 2016;73(4):384-385. doi:10.1001/jamaneurol.2015.4993

Autism Screening or Smoke Screen and Mirrors?

Abstract Full Text
JAMA Neurol. 2016;73(4):386-387. doi:10.1001/jamaneurol.2016.0126
Original Investigation

Efforts in Epilepsy Prevention in the Last 40 Years: Lessons From a Large Nationwide Study

Abstract Full Text
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JAMA Neurol. 2016;73(4):390-395. doi:10.1001/jamaneurol.2015.4515

This study using a long-term national register aims to determine whether progress has been made in the prevention of epilepsy in Finland during the last 40 years.

Prediction of Early Recurrence After Acute Ischemic Stroke

Abstract Full Text
free access
JAMA Neurol. 2016;73(4):396-401. doi:10.1001/jamaneurol.2015.4949

This study tests the validity of a prognostic score that was exclusively developed to predict early risk of recurrence in a multicenter setting.

Factors Associated With 8-Year Mortality in Older Patients With Cerebral Small Vessel Disease: The Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC) Study

Abstract Full Text
free access
JAMA Neurol. 2016;73(4):402-409. doi:10.1001/jamaneurol.2015.4560

This observational study examines factors affecting 8-year mortality in elderly patients with cerebral small vessel disease.

Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis

Abstract Full Text
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JAMA Neurol. 2016;73(4):410-416. doi:10.1001/jamaneurol.2015.4791

This cohort study examines the association between the use of proton pump inhibitors and the risk of incident dementia in an elderly German population.

Clinical and Immunological Features of Opsoclonus-Myoclonus Syndrome in the Era of Neuronal Cell Surface Antibodies

Abstract Full Text
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JAMA Neurol. 2016;73(4):417-424. doi:10.1001/jamaneurol.2015.4607

This cohort study examines the clinical and immunological features of 114 patients with opsoclonus-myoclonus syndrome, including their neuronal cell surface antibodies.

The Role of APOE in the Occurrence of Frontotemporal Dementia in Amyotrophic Lateral Sclerosis

Abstract Full Text
free access
JAMA Neurol. 2016;73(4):425-430. doi:10.1001/jamaneurol.2015.4773

This study assesses the influence of the APOE and C9ORF72 genotypes on cognitive impairment in a population-based series of Italian patients with amyotrophic lateral sclerosis.

Cognitive Decline in a Colombian Kindred With Autosomal Dominant Alzheimer Disease: A Retrospective Cohort Study

Abstract Full Text
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JAMA Neurol. 2016;73(4):431-438. doi:10.1001/jamaneurol.2015.4851

This study evaluates the onset and rate of cognitive decline during preclinical autosomal dominant Alzheimer disease and the effect of socioeconomic, vascular, and genetic factors on the cognitive decline.

Decline in Weight and Incident Mild Cognitive Impairment: Mayo Clinic Study of Aging

Abstract Full Text
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JAMA Neurol. 2016;73(4):439-446. doi:10.1001/jamaneurol.2015.4756

This cohort study investigates the association between midlife change in weight and body mass index and onset of mild cognitive impairment.

Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease

Abstract Full Text
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JAMA Neurol. 2016;73(4):447-455. doi:10.1001/jamaneurol.2015.4885

This interval-cohort study aims to establish a more powerful and meaningful clinical trial method in sporadic Creutzfeldt-Jakob disease.

Metabolic Syndrome and the Risk of Mild Cognitive Impairment and Progression to Dementia: Follow-up of the Singapore Longitudinal Ageing Study Cohort

Abstract Full Text
free access
JAMA Neurol. 2016;73(4):456-463. doi:10.1001/jamaneurol.2015.4899

This longitudinal study investigates the association of the metabolic syndrome and its component cardiovascular risk factors with the incidence of mild cognitive impairment and its progression to dementia.

Review

Evidence on Use of Neuroimaging for Surgical Treatment of Temporal Lobe Epilepsy: A Systematic Review

Abstract Full Text
JAMA Neurol. 2016;73(4):464-470. doi:10.1001/jamaneurol.2015.4996

This systematic review assesses the prognostic importance of neuroimaging techniques, including magnetic resonance imaging, positron-emission technology, and single-photon emission computed tomography, used in presurgical evaluation of patients with temporal lobe epilepsy.

Images in Neurology

Bulging and Pulsating Conjunctiva

Abstract Full Text
has multimedia
JAMA Neurol. 2016;73(4):472-473. doi:10.1001/jamaneurol.2015.4435

A 28-year-old woman presented with complaints of acute-onset severe bursting headache with vomiting for 7 days and pain, redness, swelling of eyelids, and bulging of the right eye for 2 days.

Domino-Style Cerebral Bleeding in a Patient With Immune Thrombocytopenic Purpura

Abstract Full Text
JAMA Neurol. 2016;73(4):474-475. doi:10.1001/jamaneurol.2015.4508

This case report describes a patient (who previously received a diagnosis of immune thrombocytopenic purpura) admitted to the hospital with disturbed activity, ataxic gait, and subacute onset of apathy.

Observation

Amyloid Neuropathy Following Domino Liver Transplantation: Response to Diflunisal

Abstract Full Text
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JAMA Neurol. 2016;73(4):477-478. doi:10.1001/jamaneurol.2015.4715

This case report describes possible stabilization of liver transplant–acquired amyloid neuropathy with diflunisal.

Comment & Response

Applying the Principles of McDonaldization to Medicine

Abstract Full Text
JAMA Neurol. 2016;73(4):478-479. doi:10.1001/jamaneurol.2015.4719

Applying the Principles of McDonaldization to Medicine—Reply

Abstract Full Text
JAMA Neurol. 2016;73(4):479. doi:10.1001/jamaneurol.2015.4722

Understanding Conflicting Neuropathological Findings

Abstract Full Text
JAMA Neurol. 2016;73(4):479-480. doi:10.1001/jamaneurol.2015.4879

Breastfeeding and Disease-Modifying Therapy for Multiple Sclerosis

Abstract Full Text
JAMA Neurol. 2016;73(4):480. doi:10.1001/jamaneurol.2015.4818

Breastfeeding and Disease-Modifying Therapy for Multiple Sclerosis—Reply

Abstract Full Text
JAMA Neurol. 2016;73(4):480-481. doi:10.1001/jamaneurol.2015.4821
Correction

Error in Term Definition

Abstract Full Text
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JAMA Neurol. 2016;73(4):481. doi:10.1001/jamaneurol.2016.0070

Error in Funding/Support

Abstract Full Text
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JAMA Neurol. 2016;73(4):481. doi:10.1001/jamaneurol.2016.0071

Affiliation Error in Group Information Listing

Abstract Full Text
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JAMA Neurol. 2016;73(4):481. doi:10.1001/jamaneurol.2016.0104

Omitted Author Affiliation

Abstract Full Text
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JAMA Neurol. 2016;73(4):481. doi:10.1001/jamaneurol.2016.0183

Error in Table 1

Abstract Full Text
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JAMA Neurol. 2016;73(4):481. doi:10.1001/jamaneurol.2016.0226
Obituary

In Memoriam: John F. Kurtzke, MD (1926-2015): A Founding Father of Neuroepidemiology and Pioneer of Modern Clinical Trial Design

Abstract Full Text
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JAMA Neurol. 2016;73(4):482-483. doi:10.1001/jamaneurol.2016.0030
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2016;73(4):371. doi:10.1001/jamaneurol.2015.2450
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