Tafadzwa Machipisa, MPhil; Michael Chong, MSc; Babu Muhamed, PhD; et al.
free access
JAMA Cardiol. 2021;6(9):1000-1011. doi:10.1001/jamacardio.2021.1627
This genome-wide association study identifies common genetic loci associated with rheumatic heart disease susceptibility in Black African individuals.
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Editor's Note
Expanding Discovery in Cardiovascular Genome-Wide Association Studies
Pradeep Natarajan, MD, MMSc; Elizabeth M. McNally, MD, PhD
JAMA Cardiol
Liang Guo, PhD; Sho Torii, MD, PhD; Raquel Fernandez, BS; et al.
free access
JAMA Cardiol. 2021;6(9):1013-1022. doi:10.1001/jamacardio.2021.1573
This genetic association study investigates cases of unexplained sudden cardiac death to determine the frequency of pathogenic or likely pathogenic genetic variants of inherited cardiomyopathies and arrhythmia syndromes.
Harvey D. White, DSc; Sean M. O鈥橞rien, PhD; Karen P. Alexander, MD; et al.
free access
JAMA Cardiol. 2021;6(9):1023-1031. doi:10.1001/jamacardio.2021.1651
This prespecified analysis of the ISCHEMIA randomized clinical trial compares days alive out of hospital between those receiving invasive management and conservative management, including invasive protocol鈥揳ssigned stays.
Birgit Vogel, MD; Usman Baber, MD, MS; David J. Cohen, MD, MSc; et al.
free access
JAMA Cardiol. 2021;6(9):1032-1041. doi:10.1001/jamacardio.2021.1720
This subgroup analysis of a randomized clinical trial explores differences in outcomes by sex among patients treated with ticagrelor monotherapy vs ticagrelor plus aspirin after percutaneous coronary intervention.
André Lamy, MD; Austin Browne, PhD; Tej Sheth, MD; et al.
free access
JAMA Cardiol. 2021;6(9):1042-1049. doi:10.1001/jamacardio.2021.1686
This post hoc analysis of the COMPASS randomized clinical trial investigates whether skeletonized harvesting of the internal mammary artery is associated with higher rates of graft occlusion than pedicled harvesting after coronary artery bypass graft surgery.
G. Greg Peterson, PhD, MPA; Jia Pu, PhD, MA; David J. Magid, MD, MPH; et al.
free access
JAMA Cardiol. 2021;6(9):1050-1059. doi:10.1001/jamacardio.2021.1565
This prespecified secondary analysis of a randomized clinical trial assesses whether the Million Hearts Cardiovascular Disease Risk Reduction Model increased the initiation or intensification of antihypertensive medications or statins among patients with blood pressure or low-density lipoprotein cholesterol levels above guideline thresholds for treatment intensification.
Christopher P. Cannon, MD; James A. de Lemos, MD; Robert S. Rosenson, MD; et al.
open access
JAMA Cardiol. 2021;6(9):1060-1068. doi:10.1001/jamacardio.2021.1810
This cohort study observed patients with low-density lipoprotein cholesterol levels greater than 70 mg/dL or proprotein convertase subtilisin/kexin type 9 inhibitor use for 2 years to determine treatment patterns.
Romit Bhattacharya, MD; Seyedeh Maryam Zekavat, BS; Md Mesbah Uddin, PhD; et al.
free access
JAMA Cardiol. 2021;6(9):1069-1077. doi:10.1001/jamacardio.2021.1678
This cohort study uses data from adult participants in the UK Biobank to examine whether diet quality is associated with the risk of clonal hematopoiesis of indeterminate potential and whether they are together associated with an increased risk of incident cardiovascular events and death.
Curt J. Daniels, MD; Saurabh Rajpal, MBBS, MD; Joel T. Greenshields, MS; et al.
open access
JAMA Cardiol. 2021;6(9):1078-1087. doi:10.1001/jamacardio.2021.2065
This cohort study assesses the prevalence of myocarditis in athletes with COVID-19 and compares screening strategies for safe return to play.
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Editorial
Return to Play for Athletes After COVID-19 Infection: The Fog Begins to Clear
James E. Udelson, MD; Ethan J. Rowin, MD; Barry J. Maron, MD
JAMA Cardiol