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October 2024 - April 2016

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Year

Issue

December 2021, Vol 6, No. 12, Pages 1353-1469

Original Investigation

Temporal Association Between Episodes of Atrial Fibrillation and Risk of Ischemic Stroke

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1364-1369. doi:10.1001/jamacardio.2021.3702

This case-crossover study evaluates the temporal association between episodes of atrial fibrillation and stroke in patients with cardiac implantable electronic devices.

Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes

Abstract Full Text
open access has active quiz
JAMA Cardiol. 2021;6(12):1371-1379. doi:10.1001/jamacardio.2021.3370

This cohort study of individuals with early-onset atrial fibrillation examines the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes.

Comparison of Long-term Clinical Outcomes of Skeletonized vs Pedicled Internal Thoracic Artery Harvesting Techniques in the Arterial Revascularization Trial

Abstract Full Text
free access has audio
JAMA Cardiol. 2021;6(12):1380-1386. doi:10.1001/jamacardio.2021.3866

This post hoc analysis of the Arterial Revascularization Trial compares the long-term clinical outcomes of skeletonized and pedicled internal thoracic artery harvesting for coronary artery bypass surgery.

Effect of Goal-Setting Approaches Within a Gamification Intervention to Increase Physical Activity Among Economically Disadvantaged Adults at Elevated Risk for Major Adverse Cardiovascular Events: The ENGAGE Randomized Clinical Trial

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1387-1396. doi:10.1001/jamacardio.2021.3176

This randomized clinical trial examines the use of differing methods of goal setting and implementation in gamification of individuals at risk for major cardiovascular events.

Associations of High-Sensitivity Troponin and Natriuretic Peptide Levels With Outcomes After Intensive Blood Pressure Lowering: Findings From the SPRINT Randomized Clinical Trial

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1397-1405. doi:10.1001/jamacardio.2021.3187

This post hoc analysis of SPRINT examines whether elevated high-sensitivity cardiac troponin T and N-terminal pro–B-type natriuretic peptide levels can identify individuals with the greatest risk for mortality and heart failure and the largest benefit from intensive systolic blood pressure lowering.

Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1406-1413. doi:10.1001/jamacardio.2021.3508

This cohort study evaluates the association between low-density lipoprotein cholesterol and development of cardiovascular disease later in life.

Potential Implications of Expanded US Food and Drug Administration Labeling for Sacubitril/Valsartan in the US

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1415-1423. doi:10.1001/jamacardio.2021.3651

This decision analytical model study quantifies newly eligible treatment candidates for sacubitril/valsartan under the expanded US Food and Drug Administration labeling and uses data from the PARAGON-HF trial to evaluate treatment effects and the number needed to treat to prevent 1 worsening HF event.

Association of Mortality With Aortic Stenosis Severity in Outpatients: Results From the VALVENOR Study

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1424-1431. doi:10.1001/jamacardio.2021.3718

This cohort study assesses the natural history of outpatients with native aortic stenosis based on a large regionwide population study with inclusion by all cardiologists regardless of their mode of practice.

Gender Differences in Medicare Payments Among Cardiologists

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1432-1439. doi:10.1001/jamacardio.2021.3385

This cross-sectional study determines whether gender differences exist in the reimbursements, charges, and reimbursement per charge from the Centers for Medicare & Medicaid Services.

Brief Report

Interleukin 6 and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Chronic Coronary Syndrome

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1440-1445. doi:10.1001/jamacardio.2021.3079

This cohort study outlines the associations and interactions between interleukin 6, chronic kidney disease, and the risk of major cardiovascular outcomes in patients with chronic coronary syndrome.

Association of Myocarditis With BNT162b2 Messenger RNA COVID-19 Vaccine in a Case Series of Children

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1446-1450. doi:10.1001/jamacardio.2021.3471

This case series reviews comprehensive cardiac imaging in children with myocarditis after COVID-19 vaccine.

Research Letter

Premature Menopause and 10-Year Risk Prediction of Atherosclerotic Cardiovascular Disease

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1463-1465. doi:10.1001/jamacardio.2021.3490

This cohort study assesses whether adding premature menopause status to pooled cohort equations improves risk prediction of atherosclerotic cardiovascular disease among women.

Viewpoint

The Challenge of Estimating Treatment Effects in Cardiac Surgery

Abstract Full Text
JAMA Cardiol. 2021;6(12):1355-1356. doi:10.1001/jamacardio.2021.4833

This Viewpoint discusses how the estimates of treatment effects are not qualitatively and quantitively similar between observational studies and randomized clinical trials in cardiac surgery studies.

Editorial

An Expanded Heart Failure Indication for Sacubitril/Valsartan: Evolving the Evidence Bar

Abstract Full Text
JAMA Cardiol. 2021;6(12):1357-1358. doi:10.1001/jamacardio.2021.3658

Early-Onset Atrial Fibrillation and Heritable Heart Disease—To Test or Not to Test?

Abstract Full Text
JAMA Cardiol. 2021;6(12):1359-1361. doi:10.1001/jamacardio.2021.3367

Coronary Artery Bypass Grafting With the Internal Thoracic Artery: A Great Operation With Some Unanswered Questions

Abstract Full Text
has audio
JAMA Cardiol. 2021;6(12):1362-1363. doi:10.1001/jamacardio.2021.3863
Review

Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine–Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1451-1460. doi:10.1001/jamacardio.2021.3444

This narrative review evaluates the current evidence regarding pharmacological treatments, including anticoagulants, immunoglobulin therapy, steroids, and other molecules, in the management of vaccine-induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis (CVST) postvaccination, as well as the clinical characteristics and pathophysiology of this emerging disorder.

JAMA Cardiology Clinical Challenge

Multiple Systemic Lesions in a Middle-aged Woman With a History of Lymphoma

Abstract Full Text
has multimedia
JAMA Cardiol. 2021;6(12):1461-1462. doi:10.1001/jamacardio.2021.3566

A woman in her mid-60s with a history of lymphoma presents with dyspnea, fatigue, general malaise, and presyncope. What would you do next?

Cardiovascular Images

Recurrent Paravalvular Leak Following Mitral Valve Replacement

Abstract Full Text
online only
JAMA Cardiol. 2021;6(12):e213737. doi:10.1001/jamacardio.2021.3737

This case report describes a man in his 70s who presented with acute decompensated heart failure due to recurrent severe mitral paravalvular leak.

Comment & Response

Assessing Performance of Machine Learning

Abstract Full Text
JAMA Cardiol. 2021;6(12):1465. doi:10.1001/jamacardio.2021.3712

Assessing Performance of Machine Learning—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(12):1466. doi:10.1001/jamacardio.2021.3715

Early-Life Initiation of Primary Prevention Strategies to Reduce Atherosclerosis Risk

Abstract Full Text
JAMA Cardiol. 2021;6(12):1466-1467. doi:10.1001/jamacardio.2021.3954

Early-Life Initiation of Primary Prevention Strategies to Reduce Atherosclerosis Risk—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(12):1467-1468. doi:10.1001/jamacardio.2021.3951

Safety of the 4PEPS in Patients With a Very Low Prevalence of Pulmonary Embolism—Need for More Than a Point Estimate

Abstract Full Text
JAMA Cardiol. 2021;6(12):1468. doi:10.1001/jamacardio.2021.4014

Safety of the 4PEPS in Patients With a Very Low Prevalence of Pulmonary Embolism—Need for More Than a Point Estimate—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(12):1468-1469. doi:10.1001/jamacardio.2021.4011
Editor's Note

It’s Time to Rethink (and Retrial) Our Framework for Stroke Prevention in Atrial Fibrillation

Abstract Full Text
JAMA Cardiol. 2021;6(12):1370. doi:10.1001/jamacardio.2021.3709

Transforming the Paradigm for Lipid Lowering

Abstract Full Text
JAMA Cardiol. 2021;6(12):1414. doi:10.1001/jamacardio.2021.3517
Correction

Errors in Key Points, Abstract, Results, and Figures

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1469. doi:10.1001/jamacardio.2021.4325

Errors in Table 3

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1469. doi:10.1001/jamacardio.2021.4489
JAMA Cardiology Masthead

JAMA Cardiology

Abstract Full Text
free access
JAMA Cardiol. 2021;6(12):1353. doi:10.1001/jamacardio.2020.4594
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