Gundula Povysil, MD, PhD; Olympe Chazara, PhD; Keren J. Carss, PhD; et al.
free access
JAMA Cardiol. 2021;6(4):379-386. doi:10.1001/jamacardio.2020.6500
This gene-based collapsing analysis assesses the contribution of rare variants to all-cause heart failure with and without reduced left ventricular ejection fraction.
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Editor's Note
Genetic Contribution to Common Heart Failure鈥擭ot So Rare?
Elizabeth M. McNally, MD, PhD; Christopher J. O鈥橠onnell, MD, MPH
JAMA Cardiol
Shreya Rao, MD, MPH; Matthew W. Segar, MD, MS; Adam P. Bress, PharmD, MS; et al.
free access
JAMA Cardiol. 2021;6(4):388-398. doi:10.1001/jamacardio.2020.6566
This post hoc analysis of data from the Systolic Blood Pressure Intervention Trial determines the association between the proportion of West African ancestry with response to antihypertensive medication, blood pressure control, kidney function, and risk of adverse cardiovascular events among self-identified Black individuals.
Mario Gaudino, MD, MSCE; Zaza Samadashvili, MD; Irbaz Hameed, MD; et al.
free access
has audio
JAMA Cardiol. 2021;6(4):401-409. doi:10.1001/jamacardio.2020.6585
This cohort study compares the outcomes of the use of multiple arterial grafts vs a single arterial graft during coronary artery bypass grafting for women and men.
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Podcast:
Sex Differences in Multiple vs Single Arterial Grafting
Philip Urban, MD; John Gregson, PhD; Ruth Owen, MSc; et al.
free access
JAMA Cardiol. 2021;6(4):410-419. doi:10.1001/jamacardio.2020.6814
This prognostic study develops and validates models to predict the risks of major bleeding (Bleeding Academic Research Consortium types 3-5 bleeding) and myocardial infarction and/or stent thrombosis for individual patients at high bleeding risk.
Prahlad Karki, MD; Surendra Uranw, MPH; Santosh Bastola, MSc; et al.
open access
has audio
JAMA Cardiol. 2021;6(4):420-426. doi:10.1001/jamacardio.2020.7050
This cluster randomized clinical trial investigates the effect of systematic echocardiographic screening in combination with secondary antibiotic prophylaxis on the prevalence of rheumatic heart disease in schoolchildren in Nepal.
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Podcast:
Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren
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Editorial
Screening for Rheumatic Heart Disease鈥擰uo Vadis?
Kumar Narayanan, MD, DM; Xavier Jouven, MD, PhD; Eloi Marijon, MD, PhD
JAMA Cardiol
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Podcast:
Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren
JoAnn Lindenfeld, MD; William T. Abraham, MD; Paul A. Grayburn, MD; et al.
free access
JAMA Cardiol. 2021;6(4):427-436. doi:10.1001/jamacardio.2020.7200
This secondary analysis of the COAPT randomized clinical trial explores the contributions of the degree of secondary mitral regurgitation using the effective regurgitation orifice area, regurgitant volume, and left ventricular end-diastolic volume index to the benefit of transcatheter mitral valve repair.
Sagar B. Dugani, MD, PhD; M. Vinayaga Moorthy, PhD; Chunying Li, MPH; et al.
free access
JAMA Cardiol. 2021;6(4):437-447. doi:10.1001/jamacardio.2020.7073
This cohort study evaluates risk factors associated with incident coronary heart disease in women by age at onset.
Sven-Oliver Tröbs, MD; Jürgen H. Prochaska, MD; Sören Schwuchow-Thonke, MD, MHBA; et al.
free access
JAMA Cardiol. 2021;6(4):448-456. doi:10.1001/jamacardio.2020.7184
This cohort study examines the use of global longitudinal strain as a tool to assess cardiac function and prognostic factors in patients with heart failure.