Anders M. Greve, MD, PhD; Mette Christoffersen, MSc, PhD; Ruth Frikke-Schmidt, MD, DMSc; et al.
free access
has audio
JAMA Cardiol. 2021;6(3):258-266. doi:10.1001/jamacardio.2020.5969
This study evaluates whether low plasma transthyretin concentration is associated with incident heart failure in the general population.
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Podcast:
Association of Low Plasma Transthyretin Concentration With Risk of Heart Failure in the General Population
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Editorial
Misfolded Transthyretin as a Novel Risk Factor for Heart Failure: A Rich History With Implications for Future Diagnosis and Treatment
Sanjiv J. Shah, MD
JAMA Cardiol
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Podcast:
Association of Low Plasma Transthyretin Concentration With Risk of Heart Failure in the General Population
Muthiah Vaduganathan, MD, MPH; Stephen J. Greene, MD; Shuaiqi Zhang, MS; et al.
free access
JAMA Cardiol. 2021;6(3):267-275. doi:10.1001/jamacardio.2020.5864
This cohort study evaluates candidacy for initiation of dapagliflozin based on the US Food and Drug Administration label among contemporary US patients with heart failure with reduced ejection fraction and describes potential barriers to therapeutic optimizations.
Yuanjie Pang, DPhil; Christiana Kartsonaki, DPhil; Jun Lv, PhD; et al.
open access
JAMA Cardiol. 2021;6(3):276-286. doi:10.1001/jamacardio.2020.6041
This subcohort study of Chinese adults examines the observational and genetic associations of adiposity with proteomics and the observational associations of adiposity with cardiovascular disease.
Mark Trinder, MSc; Md Mesbah Uddin, PhD; Phoebe Finneran, BS; et al.
open access
JAMA Cardiol. 2021;6(3):287-295. doi:10.1001/jamacardio.2020.5398
This study investigates whether a genetic risk score comprising 43 variants at the LPA gene, which encodes apolipoprotein(a), has clinical utility in assessing atherosclerotic cardiovascular disease risk compared with and in addition to lipoprotein(a) measurement.
Paul S. Chan, MD, MSc; Saket Girotra, MD, SM; Yuanyuan Tang, PhD; et al.
free access
JAMA Cardiol. 2021;6(3):296-303. doi:10.1001/jamacardio.2020.6210
This registry-based study compares out-of-hospital cardiac arrest outcomes in the first few weeks of the coronavirus disease 2019 pandemic in 2020 with outcomes in the same period in 2019.
Derek P. Chew, MBBS, MPH, PhD; Karice Hyun, PhD; Erin Morton, PhD; et al.
free access
JAMA Cardiol. 2021;6(3):304-313. doi:10.1001/jamacardio.2020.6314
This randomized clinical trial assesses the effect of routine Global Registries of Acute Coronary Events risk score implementation on guideline-indicated treatments and clinical outcomes of hospitalized patients with acute coronary syndrome.
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Invited Commentary
Risk Stratification Science Goes to a New Level
Robert A. Harrington, MD; E. Magnus Ohman, MBBS
JAMA Cardiol
Timothy W. Churchill, MD; Bradley J. Petek, MD; Meagan M. Wasfy, MD; et al.
free access
JAMA Cardiol. 2021;6(3):316-325. doi:10.1001/jamacardio.2020.6088
This cross-sectional study describes electrocardiographic and echocardiographic findings in healthy elite US soccer players.