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November 18, 2024
Brief Report

Early Adoption of Sodium-Glucose Cotransporter-2 Inhibitor in Patients Hospitalized With Heart Failure With Mildly Reduced or Preserved Ejection Fraction

Abstract Full Text
free access
JAMA Cardiol. Published online November 18, 2024. doi:10.1001/jamacardio.2024.4489

This cohort study evaluated adoption rates of sodium-glucose cotransporter-2 inhibitors at US hospitals for patients with heart failure and mildly reduced or preserved left ventribular ejection fraction.

Research Letter

Semaglutide Eligibility Across All Current Indications for US Adults

Abstract Full Text
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JAMA Cardiol. Published online November 18, 2024. doi:10.1001/jamacardio.2024.4657

This cross-sectional study uses National Health and Nutrition Examination Survey data to examine the number of US adults eligible for semaglutide across all current indications.

November 17, 2024
Original Investigation

Finerenone, Serum Potassium, and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction

Abstract Full Text
open access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4539

This multicenter secondary analysis of the FINEARTS-HF randomized clinical trial examines the treatment effect of finerenone, relative to placebo, on clinical outcomes based on postrandomization potassium levels.

Kidney Outcomes in Transthyretin Amyloid Cardiomyopathy

Abstract Full Text
open access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4578

This single-center cohort study assesses the prognostic importance of a decline in kidney function as assessed by estimated glomerular filtration rate in a large cohort of patients with transthyretin amyloid cardiomyopathy.

Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4613

This prespecified secondary analysis of a randomized clinical trial examines the efficacy and safety of finerenone in women and men with heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction.

Partial Cardiac Denervation to Prevent Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: The pCAD-POAF Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4639

This randomized clinical trial examines whether a partial cardiac denervation procedure reduces the incidence of postoperative atrial fibrillation among patients undergoing isolated coronary artery bypass grafting (CABG) in China.

Electronic Nudges and Influenza Vaccination Among Patients With a History of Myocardial Infarction: Insights From 3 Nationwide Randomized Clinical Trials

Abstract Full Text
free access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4648

This randomized clinical trial investigates if behavioral nudges delivered electronically that highlight the cardiovascular benefits of vaccination improve influenza vaccine uptake in patients with acute myocardial infarction (AMI).

Invited Commentary

The Fine Art and Science of Translating Trials Results Into Clinical Practice

Abstract Full Text
free access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4550

Power of Digital Nudges to Boost Influenza Vaccination Rates

Abstract Full Text
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4692
Editor's Note

Sex-Specific Efficacy and Safety in HF Trials: Inclusion Is Only the First Step

Abstract Full Text
free access
JAMA Cardiol. Published online November 17, 2024. doi:10.1001/jamacardio.2024.4624
November 16, 2024
Research Letter

Heart Failure in Zero Gravity—External Constraint and Cardiac Hemodynamics

Abstract Full Text
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JAMA Cardiol. Published online November 16, 2024. doi:10.1001/jamacardio.2024.4596

In this case series study, pulmonary artery systolic, diastolic, and mean pressures of 2 participants with obesity and heart failure with preserved ejection fraction were measured at zero gravity during parabolic flight to assess the effect of external constraint on left ventricular filling pressures.

November 15, 2024
Original Investigation

Interpreting Population Mean Treatment Effects in the Kansas City Cardiomyopathy Questionnaire: A Patient-Level Meta-Analysis

Abstract Full Text
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JAMA Cardiol. Published online November 15, 2024. doi:10.1001/jamacardio.2024.4470

This patient-level meta-analysis of a variety of randomized clinical trials examines the association between mean Kansas City Cardiomyopathy Questionnaire treatment effects and the absolute differences in the proportion of patients experiencing clinically meaningful improvement.

Editor's Note

Interpreting Health Status Measures in Patients With Heart Failure—What Counts

Abstract Full Text
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JAMA Cardiol. Published online November 15, 2024. doi:10.1001/jamacardio.2024.4610
November 13, 2024
Original Investigation

Bidirectional Risk Modulator and Modifier Variant of Dilated and Hypertrophic Cardiomyopathy in BAG3

Abstract Full Text
JAMA Cardiol. Published online November 13, 2024. doi:10.1001/jamacardio.2024.3547

This cross-sectional study evaluates the association of BAG3 genetic variation with penetrance and longitudinal outcomes of dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM).

JAMA Cardiology Patient Page

Clonal Hematopoiesis of Indeterminate Potential

Abstract Full Text
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JAMA Cardiol. Published online November 13, 2024. doi:10.1001/jamacardio.2024.3773

This JAMA Cardiology Patient Page describes clonal hematopoiesis of indeterminate potential (CHIP).

Comment & Response

Emergency Medical Service Agency Cardiac Arrest Practices

Abstract Full Text
JAMA Cardiol. Published online November 13, 2024. doi:10.1001/jamacardio.2024.3957

Emergency Medical Service Agency Cardiac Arrest Practices—Reply

Abstract Full Text
JAMA Cardiol. Published online November 13, 2024. doi:10.1001/jamacardio.2024.3954
November 6, 2024
Original Investigation

Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease

Abstract Full Text
JAMA Cardiol. Published online November 6, 2024. doi:10.1001/jamacardio.2024.3738

This genomewide association study examined specific genetic variants, pathways, and tissues associated with aortic stenosis independent of coronary artery disease in a meta-analysis of participants from 3 European cohorts.

Brief Report

Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation

Abstract Full Text
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JAMA Cardiol. Published online November 6, 2024. doi:10.1001/jamacardio.2024.3767

This cross-sectional study investigates the prevalence of heart failure with preserved ejection fraction (HFpEF) in severe isolated secondary tricuspid regurgitation and the performance of noninvasive measures in its detection.

Editorial

Disease Drivers in Aortic Stenosis vs Atherosclerosis

Abstract Full Text
JAMA Cardiol. Published online November 6, 2024. doi:10.1001/jamacardio.2024.3749
Comment & Response

The Role of Fat in Frailty Assessment Before Transcatheter Aortic Valve Replacement

Abstract Full Text
JAMA Cardiol. Published online November 6, 2024. doi:10.1001/jamacardio.2024.3822
Editor's Note

Heart Failure With Preserved Ejection Fraction—A Role for Invasive Hemodynamics

Abstract Full Text
JAMA Cardiol. Published online November 6, 2024. doi:10.1001/jamacardio.2024.3764
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