Douglas L. Mann, MD; Michael M. Givertz, MD; Justin M. Vader, MD; et al.
free access
has audio
JAMA Cardiol. 2022;7(1):17-25. doi:10.1001/jamacardio.2021.4567
This randomized clinical trial evaluates the use of sacubitril/valsartan therapy compared with valsartan alone in US patients with advanced chronic heart failure.
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Podcast:
Treatment With Sacubitril/Valsartan in Patients With Advanced Heart Failure and Reduced Ejection Fraction
G. Michael Felker, MD, MHS; Scott D. Solomon, MD; Brian Claggett, PhD; et al.
free access
JAMA Cardiol. 2022;7(1):26-34. doi:10.1001/jamacardio.2021.4027
This post hoc analysis of data from the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure (GALACTIC-HF) randomized clinical trial assesses the safety and efficacy of omecamtiv mecarbil for the treatment of patients with severe heart failure.
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Editor's Note
Identifying Treatments for Stage C2 Heart Failure
Clyde W. Yancy, MD, MSc; Adrian F. Hernandez, MD, MHS; Gregg C. Fonarow, MD
JAMA Cardiol
Martin Bødtker Mortensen, MD, PhD; Sara Gaur, MD, PhD; Attila Frimmer, MD; et al.
free access
JAMA Cardiol. 2022;7(1):36-44. doi:10.1001/jamacardio.2021.4406
This cohort study examines the use of coronary artery calcium score in estimating the risks for and outcomes of coronary artery disease in symptomatic patients with obstructive CAD.
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Editorial
The Potential and Pitfalls of Coronary Artery Calcium Scoring
Sadiya S. Khan, MD, MSc; Ann Marie Navar, MD, PhD
JAMA Cardiol
Katherine M. Reitz, MD, MSc; Andrew D. Althouse, PhD; Joseph Meyer, MD; et al.
free access
JAMA Cardiol. 2022;7(1):45-54. doi:10.1001/jamacardio.2021.3979
This cohort study assesses if preprocedural smoking is associated with an increased risk of early postprocedural complications following elective open and endovascular revascularization.
Liv Tybjærg Nordestgaard, MD; Mette Christoffersen, MScPharm, PhD; Bo Kobberø Lauridsen, MD, PhD; et al.
free access
JAMA Cardiol. 2022;7(1):55-64. doi:10.1001/jamacardio.2021.3728
This cohort study assesses the relative benefits and harms associated with genetic cholesteryl ester transfer protein deficiency.
Casey Crump, MD, PhD; Jan Sundquist, MD, PhD; Kristina Sundquist, MD, PhD
free access
JAMA Cardiol. 2022;7(1):65-74. doi:10.1001/jamacardio.2021.4127
This national cohort study of women in Sweden with a singleton delivery examines whether preterm delivery is associated with long-term increased risks of chronic hypertension and whether these risks are largely independent of shared familial factors.
Magdalene M. Assimon, PharmD, PhD; Patrick H. Pun, MD, MHS; Lily (Chin-Hua) Wang, PhD; et al.
free access
JAMA Cardiol. 2022;7(1):75-83. doi:10.1001/jamacardio.2021.4234
This cohort study compares the risk of sudden cardiac death with respiratory fluoroquinolone vs amoxicillin-based antibiotic treatment in patients with hemodialysis-dependent kidney failure.
Thomas M. Roston, MD, PhD; Jinhong Wei, PhD; Wenting Guo, PhD; et al.
free access
JAMA Cardiol. 2022;7(1):84-92. doi:10.1001/jamacardio.2021.4458
This cohort study uses in vitro functional characterization of candidate RyR2 variants to assess the diagnosis of calcium-release deficiency syndrome in probands and their relatives.