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September 6, 2016, Vol 316, No. 9, Pages 897-1004

This Week in JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2016;316(9):897-899. doi:10.1001/jama.2015.14458
  • Podcast: Safety of MRI in pregnancy, TB screening guidelines, topical treatment of nosebleeds in HHT, and more
Original Investigation

Effect of Bevacizumab Nasal Spray on Epistaxis Duration in Hereditary Hemorrhagic Telangectasia: A Randomized Clinical Trial

Sophie Dupuis-Girod, PhD; Alexis Ambrun, MD; Evelyne Decullier, PhD; et al.
Abstract Full Text
free access
JAMA. 2016;316(9):934-942. doi:10.1001/jama.2016.11387

This randomized trial investigates the efficacy of 3 different doses of bevacizumab nasal spray for reducing epistaxis duration in patients with hereditary hemorrhagic telangiectasia (HHT).

Effect of Topical Intranasal Therapy on Epistaxis Frequency in Patients With Hereditary Hemorrhagic Telangiectasia: A Randomized Clinical Trial

Kevin J. Whitehead, MD; Nathan B. Sautter, MD; Justin P. McWilliams, MD; et al.
Abstract Full Text
free access
JAMA. 2016;316(9):943-951. doi:10.1001/jama.2016.11724

This randomized clinical trial assesses whether topical therapy with either bevacizumab, estriol, or tranexamic acid that have differing mechanisms of action is effective in reducing hereditary hemorrhagic telangiectasia鈥搑elated epistaxis in 121 adult patients treated at 6 US centers of excellence.

Association Between MRI Exposure During Pregnancy and Fetal and Childhood Outcomes

Joel G. Ray, MD, MSc, FRCPC; Marian J. Vermeulen, BScN, MHSc; Aditya Bharatha, MD, FRCPC; et al.
Abstract Full Text
free access has multimedia has audio
JAMA. 2016;316(9):952-961. doi:10.1001/jama.2016.12126

This study analyzed Ontario, Canada, databases to assess the effect of MRI during the first trimester or MRI with gadolinium anytime during pregnancy on offspring until they were 4 years old.

  • Podcast: MRI Exposure During Pregnancy and Offspring Outcomes
Research Letter

Cardiac and Thermal Strain of Elderly Adults Exposed to Extreme Heat and Humidity With and Without Electric Fan Use

Daniel Gagnon, PhD; Steven A. Romero, PhD; Matthew N. Cramer, PhD; et al.
Abstract Full Text
free access
JAMA. 2016;316(9):989-991. doi:10.1001/jama.2016.10550

This physiology study investigates whether fan use delays elevations in heart rate and core temperature of older healthy volunteers in response to extreme heat and humidity.

US Preventive Services Task Force

Recommendation Statement

Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force
Abstract Full Text
free access has audio
JAMA. 2016;316(9):962-969. doi:10.1001/jama.2016.11046

This Recommendation Statement from the US Preventive Services Task Force recommends screening for latent tuberculosis infection in populations that are at increased risk. (B recommendation)

  • Podcast: USPSTF Recommendation: Screening for Latent Tuberculosis in Adults

Evidence Report

Primary Care Screening and Treatment for Latent Tuberculosis Infection in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force

Leila C. Kahwati, MD, MPH; Cynthia Feltner, MD, MPH; Michael Halpern, MD, PhD, MPH; et al.
Abstract Full Text
free access
JAMA. 2016;316(9):970-983. doi:10.1001/jama.2016.10357

This Evidence Report to support the 2016 update of the US Preventive Services Task Force Recommendation Statement on primary care screening for and treatment of latent tuberculosis infection in adults summarizes evidence on screening test accuracy and benefits and harms of screening and treatment.

Viewpoint

Innovations in Health Care Delivery

Nonemergency Medical Transportation: Delivering Care in the Era of Lyft and Uber

Brian W. Powers, AB; Scott Rinefort, MBA; Sachin H. Jain, MD, MBA
Abstract Full Text
JAMA. 2016;316(9):921-922. doi:10.1001/jama.2016.9970

This Viewpoint discusses options for nonemergency medical transportation to lower costs and improve patient experience.

Evolutionary Pressures on the Electronic Health Record: Caring for Complexity

Donna M. Zulman, MD, MS; Nigam H. Shah, MBBS, PhD; Abraham Verghese, MD
Abstract Full Text
JAMA. 2016;316(9):923-924. doi:10.1001/jama.2016.9538

In this Viewpoint, Abraham Verghese and colleagues discuss the failure of electronic health record technology to evolve in ways that synthesize important patient information, capture patients鈥� social and behavioral data, and reduce the time and effort required to interact with the technology.

Women鈥檚 Health and Abortion Rights: Whole Woman鈥檚 Health v Hellerstedt

Rebecca B. Reingold, JD; Lawrence O. Gostin, JD
Abstract Full Text
JAMA. 2016;316(9):925-926. doi:10.1001/jama.2016.11074

This Viewpoint discusses the impact of a recent Supreme Court decision that struck down restrictive requirements for abortion providers.

A National Trauma Care System to Achieve Zero Preventable Deaths After Injury: Recommendations From a National Academies of Sciences, Engineering, and Medicine Report

Donald M. Berwick, MD, MPP; Autumn S. Downey, PhD; Elizabeth A. Cornett
Abstract Full Text
JAMA. 2016;316(9):927-928. doi:10.1001/jama.2016.8524

This Viewpoint discusses a learning health system proposed by the National Academies of Sciences, Engineering, and Medicine that aims to ensure continuous improvement in trauma care among military personnel and civilians.

A Piece of My Mind

Five People

Ami B. Bhatt, MD
Abstract Full Text
JAMA. 2016;316(9):929-930. doi:10.1001/jama.2016.5091
Editorial

The Challenge of Latent TB Infection

Henry M. Blumberg, MD; Joel D. Ernst, MD
Abstract Full Text
JAMA. 2016;316(9):931-933. doi:10.1001/jama.2016.11021
JAMA Diagnostic Test Interpretation

Clinical Significance of a Positive Antineutrophil Cytoplasmic Antibody (ANCA) Test

Viet L. Bui, MD; Tanaz A. Kermani, MD, MS
Abstract Full Text
JAMA. 2016;316(9):984-985. doi:10.1001/jama.2016.8307

A 67-year-old woman with idiopathic pulmonary fibrosis was admitted for new-onset cough with bloody sputum following anorexia and vomiting. She had anemia, 6.5 mg/dL serum creatinine, microscopic hematuria without albuminuria, 1:80 ANA titer, 1:160 perinuclear ANCA titer, and a 63-U myeloperoxidase antibody. How do you interpret the results?

From The Medical Letter on Drugs and Therapeutics

A New Abuse-Deterrent Opioid鈥擷tampza ER

Abstract Full Text
JAMA. 2016;316(9):986-987. doi:10.1001/jama.2016.9540

This Medical Letter review summarizes a newly approved extended-release, abuse-deterrent capsule formulation of oxycodone for pain management.

Medical News & Perspectives

VA Extends New Hepatitis C Drugs to All Veterans in Its Health System

Judith Graham
Abstract Full Text
JAMA. 2016;316(9):913-915. doi:10.1001/jama.2016.8669

This Medical News article discusses recent efforts by the Department of Veterans Affairs to extend new hepatitis C treatments to all veterans within its health care system.

News From the Food and Drug Administration

Noninvasive Tremor Treatment

Rebecca Voelker, MSJ
Abstract Full Text
JAMA. 2016;316(9):918. doi:10.1001/jama.2016.11385

New Lens Helps Patients See Near, Far, and In-between

Rebecca Voelker, MSJ
Abstract Full Text
JAMA. 2016;316(9):918. doi:10.1001/jama.2016.11448

Relief From Dry Eye Disease

Rebecca Voelker, MSJ
Abstract Full Text
JAMA. 2016;316(9):918. doi:10.1001/jama.2016.11454
The JAMA Forum

The Partisan Divide on Health Care

Larry Levitt, MPP
Abstract Full Text
free access
JAMA. 2016;316(9):915-916. doi:10.1001/jama.2016.11736
Lab Reports

Study Provides Insights on ALS

Tracy Hampton, PhD
Abstract Full Text
JAMA. 2016;316(9):917. doi:10.1001/jama.2016.11071

Liquid Biopsy to Evaluate Efficacy of Cancer Therapy

Tracy Hampton, PhD
Abstract Full Text
JAMA. 2016;316(9):917. doi:10.1001/jama.2016.12068

Researchers Develop Tissue-Engineered Cartilage

Tracy Hampton, PhD
Abstract Full Text
JAMA. 2016;316(9):917. doi:10.1001/jama.2016.12070
The Art of JAMA

Nocturne: Ben Shahn

Thomas B. Cole, MD, MPH
Abstract Full Text
JAMA. 2016;316(9):910-911. doi:10.1001/jama.2015.14460
Poetry and Medicine

The Silk Robe

Jack Coulehan, MD
Abstract Full Text
JAMA. 2016;316(9):996. doi:10.1001/jama.2016.3380
JAMA Revisited

Case Finding in Tuberculosis

Abstract Full Text
JAMA. 2016;316(9):997. doi:10.1001/jama.2015.17100
JAMA Patient Page

Screening for Latent Tuberculosis

Jill Jin, MD, MPH
Abstract Full Text
free access
JAMA. 2016;316(9):1004. doi:10.1001/jama.2016.12212
Comment & Response

Body Mass Index and All-Cause Mortality

Shilpa N. Bhupathiraju, PhD; Walter C. Willett, MD, DrPh; Frank B. Hu, MD, PhD
Abstract Full Text
JAMA. 2016;316(9):991. doi:10.1001/jama.2016.10282

Body Mass Index and All-Cause Mortality

Zhiqiang Wang, PhD
Abstract Full Text
JAMA. 2016;316(9):991-992. doi:10.1001/jama.2016.10288

Body Mass Index and All-Cause Mortality鈥擱eply

Shoaib Afzal, MD, PhD; Børge G. Nordestgaard, MD, DMSc
Abstract Full Text
JAMA. 2016;316(9):992. doi:10.1001/jama.2016.10297

Informed Consent and the Reasonable-Patient Standard

Barry G. Main, PhD, MRCS, MFDS; Angus McNair, PhD, MRCS; Jane M. Blazeby, MD, FRCS
Abstract Full Text
JAMA. 2016;316(9):992-993. doi:10.1001/jama.2016.10555

Informed Consent and the Reasonable-Patient Standard

Brian C. Drolet, MD; Jonathan P. Brower, MD
Abstract Full Text
JAMA. 2016;316(9):993. doi:10.1001/jama.2016.10558

Informed Consent and the Reasonable-Patient Standard鈥擱eply

Erica S. Spatz, MD, MHS; Harlan M. Krumholz, MD, SM; Benjamin W. Moulton, JD, MPH
Abstract Full Text
JAMA. 2016;316(9):993-994. doi:10.1001/jama.2016.10561

Methylphenidate for Attention-Deficit/Hyperactivity Disorder

Marcel Romanos, MD; Andreas Reif, MD; Tobias Banaschewski, MD, PhD
Abstract Full Text
JAMA. 2016;316(9):994-995. doi:10.1001/jama.2016.10279

Methylphenidate for Attention-Deficit/Hyperactivity Disorder鈥擱eply

Ole Jakob Storebø, MA, PhD; Erik Simonsen, MD, PhD; Christian Gluud, MD, Dr Med Sci
Abstract Full Text
JAMA. 2016;316(9):995. doi:10.1001/jama.2016.10300
Correction

Errors in Tables and Reference Citations

Abstract Full Text
free access
JAMA. 2016;316(9):995. doi:10.1001/jama.2016.11456

Factual Error in Questions and Discussion

Abstract Full Text
free access
JAMA. 2016;316(9):995. doi:10.1001/jama.2016.11657
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2016;316(9):901-902. doi:10.1001/jama.2015.14459

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