The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) Investigators
open access
JAMA Oncol. 2022;8(3):345-353. doi:10.1001/jamaoncol.2021.6628
This randomized clinical trial of patients with a primary bone tumor or a soft tissue sarcoma compares the effects of a 5-day vs 1-day regimen of postoperative, prophylactic, intravenous antibiotics on surgical site infections within 1 year after surgery.
Shawn H. R. Lee, MBBS; Federico Antillon-Klussmann, MD; Deqing Pei, MS; et al.
free access
JAMA Oncol. 2022;8(3):354-363. doi:10.1001/jamaoncol.2021.6826
This genomic association study evaluates the association of genetic ancestry with childhood acute lymphoblastic leukemia (ALL) molecular subtypes and outcomes of modern acute lymphoblastic leukemia therapy.
C. Jillian Tsai, MD, PhD; Sean M. McBride, MD, MPH; Nadeem Riaz, MD, MS; et al.
free access
JAMA Oncol. 2022;8(3):364-372. doi:10.1001/jamaoncol.2021.6416
This cohort study summarizes 2-year follow-up of patients with human papillomavirus–associated oropharyngeal carcinoma who received radiotherapy to subclinical regions at a reduced dose and target volume of 30 Gy.
Chan Yeu Pu, MD, MS; Christine M. Lusk, MPH; Christine Neslund-Dudas, PhD; et al.
free access
JAMA Oncol. 2022;8(3):374-382. doi:10.1001/jamaoncol.2021.6720
This study compares the 2021 US Preventive Services Task Force lung cancer screening criteria with other lung cancer screening criteria and evaluates whether the sensitivity and specificity of these criteria differ by race.
Laurent Dercle, MD, PhD; Binsheng Zhao, DSC; Mithat Gönen, PhD; et al.
free access
has audio
JAMA Oncol. 2022;8(3):385-392. doi:10.1001/jamaoncol.2021.6818
This prognostic study assesses whether a signature on computed tomographic imaging derived from tumor size, density, and shape and its change as treatment is administered can estimate overall survival in patients with advanced melanoma.
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Podcast:
Early Readout on Overall Survival of Patients With Melanoma Treated With Immunotherapy
Chao Cao, MPH; Christine M. Friedenreich, PhD; Lin Yang, PhD
free access
JAMA Oncol. 2022;8(3):395-403. doi:10.1001/jamaoncol.2021.6590
This prospective cohort examines independent and joint associations of daily sitting time and physical activity with mortality outcomes among a nationally representative sample of cancer survivors during more than 4 years of follow-up.
Guru Subramanian Guru Murthy, MD, MS; Soyoung Kim, PhD; Zhen-Huan Hu, MPH; et al.
free access
JAMA Oncol. 2022;8(3):404-411. doi:10.1001/jamaoncol.2021.6846
This cohort study of adults with myelodysplastic syndrome assesses whether the use of younger matched unrelated donors for allogeneic hematopoietic cell transplantation is associated with better outcomes than the use of older matched sibling donors.
Roman O. Kowalchuk, MD; Benjamin A. Johnson-Tesch, MD; Joseph T. Marion, MD; et al.
free access
JAMA Oncol. 2022;8(3):412-419. doi:10.1001/jamaoncol.2021.7008
This cohort study examines a risk stratification model for vertebral compression fracture after stereotactic body radiation therapy.
Global Burden of Disease 2019 Cancer Collaboration
open access
JAMA Oncol. 2022;8(3):420-444. doi:10.1001/jamaoncol.2021.6987
The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 examines cancer burden and trends globally for 204 countries and territories and by Socio-demographic Index quintiles from 2010 to 2019.
Breast Cancer Association Consortium
open access
online only
JAMA Oncol. 2022;8(3):e216744. doi:10.1001/jamaoncol.2021.6744
This case-control study examines tumors associated with breast cancer susceptibility genes in large-scale population- or hospital-based studies.
Amar U. Kishan, MD; Alison Steigler, BMath; James W. Denham, MD; et al.
open access
online only
JAMA Oncol. 2022;8(3):e216871. doi:10.1001/jamaoncol.2021.6871
This cohort study explores associations between the duration of androgen deprivation therapy and distant metastasis-free survival in men undergoing external beam radiotherapy with and without a brachytherapy boost for treatment of high-risk prostate cancer.