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October 2024 - April 2015

Decade

Year

Issue

December 2022, Vol 8, No. 12, Pages 1720-1860

Original Investigation

Association of Prostate-Specific Antigen Screening Rates With Subsequent Metastatic Prostate Cancer Incidence at US Veterans Health Administration Facilities

Abstract Full Text
free access has audio
JAMA Oncol. 2022;8(12):1747-1755. doi:10.1001/jamaoncol.2022.4319

This cohort study assesses the association of prostate-specific antigen screening with incidence of metastatic prostate cancer in the Veterans Health Administration (VHA) from 2005 to 2019.

Pooled Analysis of Meningioma Risk Following Treatment for Childhood Cancer

Abstract Full Text
open access
JAMA Oncol. 2022;8(12):1756-1764. doi:10.1001/jamaoncol.2022.4425

This case-control study evaluates meningioma risk following radiotherapy and chemotherapy and identifies possible factors associated with modifying radiation-associated risk in survivors of childhood cancer.

Association of Changes in Cancer Therapy Over 3 Decades With Risk of Subsequent Breast Cancer Among Female Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study (CCSS)

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1765-1774. doi:10.1001/jamaoncol.2022.4649

This cohort study examines the association between temporal changes in cancer treatment between 1970 and 1999 and subsequent breast cancer risk among women.

Adjuvant Capecitabine Following Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: A Randomized Clinical Trial

Abstract Full Text
open access
JAMA Oncol. 2022;8(12):1776-1785. doi:10.1001/jamaoncol.2022.4656

This multicenter, open-label randomized clinical trial conducted in China compares the efficacy and safety of adjuvant capecitabine with concurrent chemoradiotherapy vs concurrent chemoradiotherapy alone for treatment of patients with locoregionally advanced nasopharyngeal carcinoma.

Clinical Trial Participation Among Older Adult Medicare Fee-for-Service Beneficiaries With Cancer

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1786-1792. doi:10.1001/jamaoncol.2022.5020

This cohort study uses a novel population-based methodology to estimate the proportion of older adult Medicare Fee-for-Service beneficiaries with cancer who participate in interventional cancer clinical trials.

Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma

Abstract Full Text
free access has audio
JAMA Oncol. 2022;8(12):1794-1801. doi:10.1001/jamaoncol.2022.5041

This cohort study investigates the association among different immunosuppressive regimens for grade 3 and higher immune-related adverse events with overall survival and progression-free survival in a homogeneous cohort of patients with advanced melanoma who were treated with first-line ipilimumab and nivolumab.

Concurrent Olaparib and Radiotherapy in Patients With Triple-Negative Breast Cancer: The Phase 1 Olaparib and Radiation Therapy for Triple-Negative Breast Cancer Trial

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1802-1808. doi:10.1001/jamaoncol.2022.5074

This phase 1 dose-escalation trial assesses the safety and tolerability of a combination of olaparib and radiotherapy in patients with triple-negative breast cancer with residual disease after neoadjuvant chemotherapy.

Association of Long-term Outcomes With Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Brain Metastasis: A Secondary Analysis of The N107C/CEC.3 (Alliance for Clinical Trials in Oncology/Canadian Cancer Trials Group) Randomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1809-1815. doi:10.1001/jamaoncol.2022.5049

This secondary analysis examines the long-term association of whole-brain radiotherapy and stereotactic radiosurgery with quality of life and cognition outcomes for patients with limited brain metastasis following surgical resection.

Brief Report

Outcomes After Treatment With Cobimetinib in Patients With Rosai-Dorfman Disease Based on KRAS and MEK Alteration Status

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1816-1820. doi:10.1001/jamaoncol.2022.4432

This cohort study assesses outcomes after treatment with cobimetinib based on MAPK pathway alterations in patients with Rosai-Dorfman disease.

Comparing Trial and Real-world Adjuvant Oxaliplatin Delivery in Patients With Stage III Colon Cancer Using a Longitudinal Cumulative Dose

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1821-1824. doi:10.1001/jamaoncol.2022.4445

This cohort study compares oxaliplatin delivery between MOSAIC trial participants and patients treated in the US Oncology Network with stage III colon cancer using a longitudinal cumulative dose.

Association of High Levels of Antidrug Antibodies Against Atezolizumab With Clinical Outcomes and T-Cell Responses in Patients With Hepatocellular Carcinoma

Abstract Full Text
open access
JAMA Oncol. 2022;8(12):1825-1829. doi:10.1001/jamaoncol.2022.4733

This cohort study examines the clinical and immunologic associations of atezolizumab antidrug antibody levels with patient outcomes after treatment with atezolizumab/bevacizumab in patients with advanced hepatocellular carcinoma.

Research Letter

Abdominal Extrarenal Involvement in Erdheim-Chester Disease in a Cohort of 304 Patients

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1843-1845. doi:10.1001/jamaoncol.2022.4536

This cohort study estimates the prevalence of nonretroperitoneal abdominal organ involvement in Erdheim-Chester disease in a large cohort of patients.

Association Between Polycystic Ovary Syndrome and Risk of Pancreatic Cancer

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1845-1847. doi:10.1001/jamaoncol.2022.4540

This case-control study sought to confirm the exploratory finding of an association between polycystic ovary syndrome and risk of pancreatic cancer.

Systemic Anticancer Therapy at the End of Life—Changes in Usage Pattern in the Immunotherapy Era

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1847-1849. doi:10.1001/jamaoncol.2022.4666

This cohort study evaluates the rate of systemic anticancer therapy use among patients dying of cancer.

Analysis of Serious Adverse Event Reporting for Patients Enrolled in Cancer Clinical Trials During the COVID-19 Pandemic

Abstract Full Text
free access has active quiz
JAMA Oncol. 2022;8(12):1849-1851. doi:10.1001/jamaoncol.2022.4919

This cross-sectional study assesses whether a change occurred in reporting of serious adverse events for patients in oncology clinical trials in the US during the COVID-19 pandemic.

Review

Practical Considerations for the Use of Circulating Tumor DNA in the Treatment of Patients With Cancer: A Narrative Review

Abstract Full Text
has active quiz
JAMA Oncol. 2022;8(12):1830-1839. doi:10.1001/jamaoncol.2022.4457

This review presents a practical overview for clinicians and allied health care professionals for selection of the most appropriate liquid biopsy assay, specifically circulating tumor DNA.

JAMA Oncology Clinical Challenge

Generalized Cutaneous Nodules on the Trunk and Extremities

Abstract Full Text
has active quiz
JAMA Oncol. 2022;8(12):1840-1841. doi:10.1001/jamaoncol.2022.4742

A 61-year-old man presented with rapidly growing and itchy cutaneous nodules all over his body and prominent lymphadenopathies. What is your diagnosis?

Viewpoint

All Optimal Dosing Roads Lead to Therapeutic Drug Monitoring—Why Take the Slow Lane

Abstract Full Text
JAMA Oncol. 2022;8(12):1733-1735. doi:10.1001/jamaoncol.2022.4452

This Viewpoint discusses therapeutic drug monitoring as a necessary treatment paradigm and the need for regulatory agencies to provide the conditions to make it happen.

A Cast of Shadow on Postoperative Radiotherapy for pIIIA-N2 Non–Small Cell Lung Cancer?

Abstract Full Text
JAMA Oncol. 2022;8(12):1735-1736. doi:10.1001/jamaoncol.2022.4442

This Viewpoint discusses 2 recent randomized clinical trials evaluating the role of mediastinal postoperative radiotherapy in patients with non–small cell lung cancer.

Reexamining Social Determinants of Health Data Collection in the COVID-19 Era

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1736-1738. doi:10.1001/jamaoncol.2022.4543

This Viewpoint describes the association of various factors, including demographic factors, disease-related factors, and social determinants of health, with cancer treatment delays among a cohort of patients across multiple sites who had all tested positive for SARS-CoV-2.

Invited Commentary

Treatment-Associated Breast Cancer Following Childhood Cancer: Where Do We Go From Here?

Abstract Full Text
JAMA Oncol. 2022;8(12):1774-1775. doi:10.1001/jamaoncol.2022.4590

Addressing Racial, Ethnic, and Age Disparities in Cancer Clinical Trial Enrollment: Time to Stop Tinkering Around the Edges

Abstract Full Text
JAMA Oncol. 2022;8(12):1792-1793. doi:10.1001/jamaoncol.2022.5006
JAMA Oncology Patient Page

PSMA PET Scan

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1860. doi:10.1001/jamaoncol.2022.3531

This JAMA Oncology Patient Page describes the PSMA PET scan, an imaging test used to detect prostate cancer throughout the body.

Cancer Care Chronicles

Throat Cancer—An Oral History

Abstract Full Text
JAMA Oncol. 2022;8(12):1739. doi:10.1001/jamaoncol.2022.3763

This essay describes the physician-turned-patient experience of standing up to cancer by lying down.

Avoiding Checkmate—Playing Chess With Cancer

Abstract Full Text
JAMA Oncol. 2022;8(12):1740. doi:10.1001/jamaoncol.2022.4422

The author of this essay uses his experience learning the complex planning and strategies of chess in childhood to illustrate the importance of informed strategy in the treatment of patients with cancer.

Comment & Response

Is the Delphi’s Oracle Pertinent to Patients With Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma?

Abstract Full Text
JAMA Oncol. 2022;8(12):1851. doi:10.1001/jamaoncol.2022.4673

Is the Delphi’s Oracle Pertinent to Patients With Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma?—Reply

Abstract Full Text
JAMA Oncol. 2022;8(12):1851-1852. doi:10.1001/jamaoncol.2022.4676

Association of 5α-Reductase Inhibitor Use With Prostate Cancer–Specific Mortality

Abstract Full Text
JAMA Oncol. 2022;8(12):1852. doi:10.1001/jamaoncol.2022.4789

Association of 5α-Reductase Inhibitor Use With Prostate Cancer–Specific Mortality—Reply

Abstract Full Text
JAMA Oncol. 2022;8(12):1852-1853. doi:10.1001/jamaoncol.2022.4792

Methodologic Concerns in Secondary Analysis of KEYNOTE-048

Abstract Full Text
JAMA Oncol. 2022;8(12):1853-1854. doi:10.1001/jamaoncol.2022.5068

Methodologic Concerns in Secondary Analysis of KEYNOTE-048—Reply

Abstract Full Text
JAMA Oncol. 2022;8(12):1854-1855. doi:10.1001/jamaoncol.2022.5071

Integrating Community Health Workers Into Care for Patients With Advanced Stages of Cancer—Fragility Index Analysis

Abstract Full Text
JAMA Oncol. 2022;8(12):1855. doi:10.1001/jamaoncol.2022.5081

Integrating Community Health Workers Into Care for Patients With Advanced Stages of Cancer—Fragility Index Analysis—Reply

Abstract Full Text
JAMA Oncol. 2022;8(12):1856. doi:10.1001/jamaoncol.2022.5084
Correction

Errors in Figure and in Table Titles

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1856. doi:10.1001/jamaoncol.2022.5671

Errors in Table 1

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1856. doi:10.1001/jamaoncol.2022.5738

Change of Article Status to Open Access

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1856. doi:10.1001/jamaoncol.2022.6336
JAMA Oncology Masthead

JAMA Oncology

Abstract Full Text
free access
JAMA Oncol. 2022;8(12):1720. doi:10.1001/jamaoncol.2021.5531
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