This randomized clinical trial compares the efficacy and safety of telaglenastat plus cabozantinib vs placebo plus cabozantinib in patients with metastatic clear-cell renal cell carcinoma.
This phase 2 nonrandomized clinical trial examines the association of cabazitaxel treatment for patients with advanced dedifferentiated liposarcoma with progression-free survival.
This cohort study of data on participants in the Cardiovascular Health Study assesses risk of lung cancer in smokers for whom low-density computed tomographic screening is not recommended.
This cohort study investigates the risk of disease-specific mortality and relapse in women who underwent fertility preservation with or without hormonal stimulation compared with women who did not at time of breast cancer diagnosis.
This randomized clinical trial assesses whether etoposide plus cisplatin or irinotecan plus cisplatin is a more effective treatment regimen in terms of overall survival in patients with advanced neuroendocrine carcinoma of the digestive system.
This systematic review and meta-analysis examines the predictive value of tissue-based PD-L1 status compared with other variables for ICI benefit among 17 randomized clinical trials including 11鈥�166 patients with advanced gastroesophageal cancer.
This cohort study describes changes between 2006 and 2016 in the use of trimodality therapy for patients with stage 2/3 rectal cancer and identifies associations with pathologic stage and survival over time.
This cohort study uses US Veterans Health Administration data to assess the association of prostate-specific antigen screening with prostate cancer鈥搒pecific mortality among non-Hispanic Black men and non-Hispanic White men.
This cohort study assesses neutralizing antibody concentrations following a third mRNA-1273 vaccination in immunocompromised patients with hematologic cancers to levels obtained in healthy individuals after the standard 2-dose vaccination schedule.
This decision analytical model study examines premature treatment discontinuation in clinical trials for patients with advanced renal cell carcinoma.
This case series investigates reports of 20 patients with colitis temporally associated with alpelisib use.
This cohort study evaluates the sociodemographic characteristics of patients with urachal cancer, cancer treatments, and the association of patient characteristics with overall survival.
This cohort study characterizes the inclusion of Hispanic ethnicity or ethnoracial categories in breast cancer studies from the National Cancer Database.
This narrative review discusses the implications of the 2021 updates to the World Health Organization (WHO) central nervous system (CNS) tumor classification relative to adult-type glioma diagnosis, prognosis, and treatment.
This Viewpoint describes the concept of race-conscious medicine in oncology.
This Viewpoint discusses the potential misinterpretations in the 2022 US Preventive Services Task Force recommendation statement on the use of aspirin for the prevention of colorectal cancer.
This Viewpoint evaluates factors introduced by the overturn of Roe v Wade that will further complicate the complex, multidisciplinary decision-making involved in treating patients with pregnancy-associated cancer.
This essay discusses how a diagnosis of breast cancer changed the author鈥檚 perspective on intersectionality, the interpersonal, disciplinary, structural, and especially cultural expectations of persons in marginalized social groups.