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November 14, 2024
Original Investigation

Toripalimab Plus Chemotherapy as a First-Line Therapy for Extensive-Stage Small Cell Lung Cancer: The Phase 3 EXTENTORCH Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.5019

This randomized clinical trial evaluates the efficacy and safety of first-line toripalimab vs placebo plus etoposide and platinum-based chemotherapy for treating patients with extensive-stage small cell lung cancer.

Research Letter

Regulatory Fate of Cancer Indications in the European Union After Accelerated Approval in the US

Abstract Full Text
JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.5145

This cohort study investigates the regulatory fate in the European Union for drugs that received accelerated approval for cancer indications in the US.

Special Communication

Advancing Global Pharmacoequity in Oncology

Abstract Full Text
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JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.5032

This Special Communication proposes building regional technology transfer hubs, streamlining and increasing the use of compulsory licenses, and enhancing price transparency as a way to meaningfully reduce cancer drug prices globally, especially for low- and middle-income countries.

Invited Commentary

Toripalimab For Extensive-Stage Small Cell Lung Cancer

Abstract Full Text
JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.4958
Comment & Response

Concerns Regarding Sample Size and Credibility of Progression-Free Survival Results

Abstract Full Text
JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.5154

Concerns Regarding Sample Size and Credibility of Progression-Free Survival Results—Reply

Abstract Full Text
JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.5151
Correction

Change of Article Status to Open Access

Abstract Full Text
free access
JAMA Oncol. Published online November 14, 2024. doi:10.1001/jamaoncol.2024.5689
November 7, 2024
Original Investigation

Long-Term Adverse Effects and Complications After Prostate Cancer Treatment

Abstract Full Text
JAMA Oncol. Published online November 7, 2024. doi:10.1001/jamaoncol.2024.4397

This cohort study assesses the long-term adverse effects and complications of prostate cancer treatment in treated patients compared with a general population of older males.

Equecabtagene Autoleucel in Patients With Relapsed or Refractory Multiple Myeloma: The FUMANBA-1 Nonrandomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online November 7, 2024. doi:10.1001/jamaoncol.2024.4879

This phase 1b/2 nonrandomized clinical trial evaluates whether equecabtagene autoleucel can benefit patients with relapsed or refractory multiple myeloma and determines the overall response rate after infusion.

Viewpoint

Financial Toxicity Among Asian American Cancer Survivors

Abstract Full Text
JAMA Oncol. Published online November 7, 2024. doi:10.1001/jamaoncol.2024.5016

This Viewpoint highlights financial toxicity specific to Asian American cancer survivors and presents steps forward within the framework of the social ecological model of health, considering individual, interpersonal, community, and policy-level dimensions.

Comment & Response

PD-L1 Expression for Tailoring Treatment in Advanced Melanoma—It Is Never That Easy

Abstract Full Text
JAMA Oncol. Published online November 7, 2024. doi:10.1001/jamaoncol.2024.4902

PD-L1 Expression for Tailoring Treatment in Advanced Melanoma—It Is Never That Easy—Reply

Abstract Full Text
JAMA Oncol. Published online November 7, 2024. doi:10.1001/jamaoncol.2024.4905
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