NEUROLOGY
Manja Koch, PhD; Annette L. Fitzpatrick, PhD; Stephen R. Rapp, PhD; et al.
This cohort study examines the association between alcohol intake and risk of dementia among older adults with or without mild cognitive impairment.
JAMA Netw Open. 2019;2(9):e1910319. doi:10.1001/jamanetworkopen.2019.10319
PUBLIC HEALTH
Nia Heard-Garris, MD, MSc; Kaitlyn Ann Sacotte, MD; Tyler N. A. Winkelman, MD, MSc; et al.
This cross-sectional study examines whether a childhood history of exposure to parental incarceration and/or juvenile justice involvement is associated with mental health outcomes in early adulthood.
JAMA Netw Open. 2019;2(9):e1910465. doi:10.1001/jamanetworkopen.2019.10465
MEDICAL EDUCATION
Elle Lett, MBiostat; H. Moses Murdock, BS; Whitney U. Orji, BS; et al.
This cross-sectional study examines trends in racial/ethnic representation among US medical school applicants and matriculants relative to the overall age-adjusted US population.
JAMA Netw Open. 2019;2(9):e1910490. doi:10.1001/jamanetworkopen.2019.10490
ONCOLOGY
Jae-Young Hong, MD, PhD; Kyungdo Han, PhD; Jin-Hyung Jung, PhD; et al.
This cohort study examines the association of low-dose radiation exposure in youths with risk of cancer using South Korean national health insurance data.
JAMA Netw Open. 2019;2(9):e1910584. doi:10.1001/jamanetworkopen.2019.10584
ONCOLOGY
Joseph M. Unger, PhD, MS; Van T. Nghiem, PhD; Dawn L. Hershman, MD, MS; et al.
This cohort study examines the association of National Cancer Institute Clinical Trial Network studies with practice influence, measured as guideline care and new drug indications for treatment of patients with cancer.
JAMA Netw Open. 2019;2(9):e1910593. doi:10.1001/jamanetworkopen.2019.10593
HEALTH POLICY
Margot L. Schwartz, MPH; Cyrus M. Kosar, MA; Tracy M. Mroz, PhD, OTR/L; et al.
This cross-sectional study compares the quality of home health agencies that serve traditional Medicare beneficiaries vs beneficiaries enrolled in high-quality or low-quality Medicare Advantage plans.
JAMA Netw Open. 2019;2(9):e1910622. doi:10.1001/jamanetworkopen.2019.10622
PHARMACY AND CLINICAL PHARMACOLOGY
Ravi J. Desai, BS; Meghan M. Good, PharmD; Alvaro San-Juan-Rodriguez, PharmD; et al.
This cross-sectional study uses data from the Veterans Health Administration and Medicaid to examine changes in varenicline prescribing from the time of US Food and Drug Administration (FDA) approval through publication and removal of public health advisories.
JAMA Netw Open. 2019;2(9):e1910626. doi:10.1001/jamanetworkopen.2019.10626
NEPHROLOGY
Aminu K. Bello, PhD; Paul E. Ronksley, PhD; Navdeep Tangri, PhD; et al.
This cross-sectional study assesses chronic kidney disease management in Canadian primary care practices to identify care gaps to guide development and implementation of national quality improvement initiatives.
JAMA Netw Open. 2019;2(9):e1910704. doi:10.1001/jamanetworkopen.2019.10704
ANESTHESIOLOGY
Karim S. Ladha, MD, MSc; Mark D. Neuman, MD, MSc; Gabriella Broms, MD, PhD; et al.
This cohort study determines whether there are differences in the frequency, amount, and type of opioids dispensed after surgery among the United States, Canada, and Sweden.
JAMA Netw Open. 2019;2(9):e1910734. doi:10.1001/jamanetworkopen.2019.10734
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Invited Commentary
Opioid Prescribing After Surgery鈥擟ause for Concern?
Lesley A. Colvin, MBChB, FRCA, PhD, FRCP, FFPMRCA
JAMA Netw Open
HEALTH INFORMATICS
Robyn Tamblyn, MSc, PhD, FCAHS, CM; Michal Abrahamowicz, PhD; David L. Buckeridge, MD, PhD; et al.
This cluster randomized trial evaluates whether electronic medication reconciliation reduces medication discrepancies, adverse drug events, and other adverse outcomes compared with usual care.
has audio
JAMA Netw Open. 2019;2(9):e1910756. doi:10.1001/jamanetworkopen.2019.10756
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Podcast:
Effect of Electronic Medication Reconciliation on Adverse Events, and Marijuana Use Patterns in Adults
NEUROLOGY
Mary Farrant, MBA; J. Donald Easton, MD; Eric E. Adelman, MD; et al.
This secondary analysis of an international randomized clinical trial investigates the results of the adjudicated end point process in the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial by comparing end points assessed by local site investigators with centrally adjudicated end points.
JAMA Netw Open. 2019;2(9):e1910769. doi:10.1001/jamanetworkopen.2019.10769
EMERGENCY MEDICINE
Amresh D. Hanchate, PhD; Michael K. Paasche-Orlow, MD, MA, MPH; William E. Baker, MD; et al.
This cohort study examines the patterns of emergency department destination of emergency medical services transport for black, Hispanic, and white Medicare beneficiaries residing in the same area.
JAMA Netw Open. 2019;2(9):e1910816. doi:10.1001/jamanetworkopen.2019.10816
PSYCHIATRY
Yohannes Adama Melaku, MPH, PhD; Sarah Appleton, PhD; Amy C. Reynolds, MSciMed(ClinEpi), PhD; et al.
This cohort study investigates the association between behavioral problems at 5, 10, and 16 years of age and self-reported insomnia symptoms at 42 years of age.
JAMA Netw Open. 2019;2(9):e1910861. doi:10.1001/jamanetworkopen.2019.10861
HEALTH POLICY
Shi Yan, BSc; Yu Heng Kwan, BSc; Julian Thumboo, MMed; et al.
This cross-sectional study using data from Singapore national health records examines the sociodemographic characteristics, health conditions, health care utilization, and health care cost patterns for different segments of a multiethnic Asian population.
JAMA Netw Open. 2019;2(9):e1910878. doi:10.1001/jamanetworkopen.2019.10878
DIABETES AND ENDOCRINOLOGY
BIRTH-GENE (BIG) Study Working Group
This mendelian randomization study examines the association of birth weight with type 2 diabetes and glycemic traits.
JAMA Netw Open. 2019;2(9):e1910915. doi:10.1001/jamanetworkopen.2019.10915
PSYCHIATRY
Danielle L. Steelesmith, PhD; Cynthia A. Fontanella, PhD; John V. Campo, MD; et al.
This cross-sectional study estimates suicide rates and trajectories in the United States, assesses associated county-level contextual factors, and explores variation across the rural-urban continuum.
JAMA Netw Open. 2019;2(9):e1910936. doi:10.1001/jamanetworkopen.2019.10936
INFECTIOUS DISEASES
Ngai Sze Wong, PhD; Kenny Chi Wai Chan, FHKAM(Med); Bonnie Chun Kwan Wong, FHKAM(Med); et al.
This decision analytical model analyzes the cost-effectiveness of latent tuberculosis infection testing for individuals in Hong Kong with HIV who had negative latent tuberculosis infection test results at baseline.
JAMA Netw Open. 2019;2(9):e1910960. doi:10.1001/jamanetworkopen.2019.10960
HEALTH INFORMATICS
Song Xu, PhD; Jason Hom, MD; Santhosh Balasubramanian, BS; et al.
This diagnostic study uses machine learning models to assess the prevalence of low-yield inpatient laboratory tests.
JAMA Netw Open. 2019;2(9):e1910967. doi:10.1001/jamanetworkopen.2019.10967
UROLOGY
Rajiv Jayadevan, MD; Ely R. Felker, MD; Lorna Kwan, MPH; et al.
This cohort study examines the association of magnetic resonance imaging (MRI)鈭抔uided confirmatory prostate biopsy findings with the risk of pathologic disease upgrading during active surveillance for prostate cancer.
JAMA Netw Open. 2019;2(9):e1911019. doi:10.1001/jamanetworkopen.2019.11019
PEDIATRICS
Daniela Ene, MSc; Geoff Der, MA, MSc; Sue Fletcher-Watson, PhD; et al.
This cohort study investigates the associations of neighborhood disadvantage, gestational age, and English as a first language with speech, language, and communication concerns at age 27 to 30 months among children in Scotland.
JAMA Netw Open. 2019;2(9):e1911027. doi:10.1001/jamanetworkopen.2019.11027
PUBLIC HEALTH
Ke Peng, MPH; Xuequan Zhu, MSc; Amy Gillespie, PhD; et al.
This survey study assesses the rates of abuse, neglect, and bullying experienced at home or in school by transgender and gender-nonbinary adolescents in China and the associations of these experiences with mental health.
JAMA Netw Open. 2019;2(9):e1911058. doi:10.1001/jamanetworkopen.2019.11058
PEDIATRICS
Tracey A. Wilkinson, MD, MPH; Stephen M. Downs, MD, MS; Brownsyne Tucker Edmonds, MD, MPH, MS
This economic evaluation study uses a cost model to analyze Indiana Medicaid鈥檚 cost savings associated with providing adolescents with same-day access to long-acting reversible contraception compared with requiring a second visit for placement.
JAMA Netw Open. 2019;2(9):e1911063. doi:10.1001/jamanetworkopen.2019.11063
ONCOLOGY
Rebecca Pedersini, MD; Vito Amoroso, MD; Filippo Maffezzoni, MD; et al.
This cross-sectional study evaluates whether fat body mass is associated with vertebral fracture prevalence among postmenopausal women undergoing adjuvant aromatase inhibitor therapy for breast cancer.
JAMA Netw Open. 2019;2(9):e1911080. doi:10.1001/jamanetworkopen.2019.11080
STATISTICS AND RESEARCH METHODS
Marianne Razavi, PhD; Paul Glasziou, MD, PhD; Farina A. Klocksieben, MS; et al.
This systematic review and meta-analysis assesses how often the US Food and Drug Administration (FDA) has authorized novel interventions based on nonrandomized clinical trials and whether there is an association of the magnitude of treatment effects with FDA requirements for additional testing.
JAMA Netw Open. 2019;2(9):e1911111. doi:10.1001/jamanetworkopen.2019.11111
PUBLIC HEALTH
Joanna Ting Wai Chu, PhD; Angela Wadham, BA; Yannan Jiang, PhD; et al.
This randomized clinical trial evaluates the effectiveness of a text-messaging program, MyTeen, for promoting parental competence and mental health literacy for parents of adolescents.
JAMA Netw Open. 2019;2(9):e1911120. doi:10.1001/jamanetworkopen.2019.11120
GENETICS AND GENOMICS
QiPing Feng, PhD; Wei-Qi Wei, MD, PhD; Sandip Chaugai, MD; et al.
This cohort study tests the associations between PCSK9 genetic variants, a PCSK9 genetic risk score, or genetically estimated PCSK9 expression levels and the risk of sepsis among patients admitted to a hospital with infection.
JAMA Netw Open. 2019;2(9):e1911130. doi:10.1001/jamanetworkopen.2019.11130
EMERGENCY MEDICINE
Kei Ouchi, MD, MPH; Tania Strout, PhD, RN, MS; Samir Haydar, DO, MPH; et al.
This cohort study examines the accuracy of clinicians鈥� assessments of mortality risk among older adults admitted to the hospital from the emergency department compared with the actual 1-month mortality of these patients.
JAMA Netw Open. 2019;2(9):e1911139. doi:10.1001/jamanetworkopen.2019.11139
ONCOLOGY
Nikhil T. Sebastian, MD; Yubo Tan, MS; Eric D. Miller, MD, PhD; et al.
This cohort study compares the overall survival of patients with metastatic intrahepatic cholangiocarcinoma treated with chemotherapy alone vs chemotherapy with definitive liver-directed local therapy.
JAMA Netw Open. 2019;2(9):e1911154. doi:10.1001/jamanetworkopen.2019.11154
GLOBAL HEALTH
Ellen Moscoe, ScD; Kawango Agot, PhD; Harsha Thirumurthy, PhD
This randomized clinical trial evaluates the effect of prize-linked savings accounts, compared with standard-interest savings accounts, on savings behavior and expenditures on alcohol, gambling, and transactional sex among men in Kenya.
JAMA Netw Open. 2019;2(9):e1911162. doi:10.1001/jamanetworkopen.2019.11162
PHYSICAL MEDICINE AND REHABILITATION
Jacqueline S. Hebert, MD; Quinn A. Boser, MSc; Aïda M. Valevicius, MSc; et al.
This cross-sectional study examines whether task selection is a factor in visuomotor adaptation strategies to perform goal-directed object movement tasks in individuals with an upper-limb prosthesis compared with individuals with normal arm function.
JAMA Netw Open. 2019;2(9):e1911197. doi:10.1001/jamanetworkopen.2019.11197
PUBLIC HEALTH
Dale A. Barnhart, ScD; Isaac Tsikhutsu, MMed; Duncan Kirui, BSc; et al.
This population-based survey study examines the extent to which the decrease in child mortality in Kenya is associated with the US President鈥檚 Emergency Plan for AIDS Relief (PEPFAR) funding for prevention of mother-to-child transmission of HIV.
JAMA Netw Open. 2019;2(9):e1911318. doi:10.1001/jamanetworkopen.2019.11318
PEDIATRICS
Alison J. Culyba, MD, PhD, MPH; Elizabeth Miller, MD, PhD; Steven M. Albert, PhD; et al.
This cross-sectional study examines associations between adult support and patterns of violence and risk and protective behavior co-occurrence among male youths in urban neighborhoods.
JAMA Netw Open. 2019;2(9):e1911375. doi:10.1001/jamanetworkopen.2019.11375
PSYCHIATRY
Bin Yu, MD, MPH; Xinguang Chen, MD, PhD
This cross-sectional study examines time trends and sex differences in the suicide mortality rate among US youths adjusted for birth cohort and age.
JAMA Netw Open. 2019;2(9):e1911383. doi:10.1001/jamanetworkopen.2019.11383
HEALTH POLICY
Carl T. Berdahl, MD, MS; Gregory J. Moran, MD; Owen McBride, MD; et al.
This case series study examines how closely documentation in electronic health records matches the review of systems and physical examination performed by emergency physicians.
JAMA Netw Open. 2019;2(9):e1911390. doi:10.1001/jamanetworkopen.2019.11390
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Invited Commentary
Electronic Health Records鈥擜 System Only as Beneficial as Its Data
Nathalie Jetté, MD, MSc, FRCPC; Churl-Su Kwon, MD, MPH, FRSPH
JAMA Netw Open
PEDIATRICS
Elizabeth A. Walshe, PhD; Flaura K. Winston, MD, PhD; Laura M. Betancourt, PhD; et al.
This cohort study investigates the association between working memory development in young drivers and motor vehicle crashes.
JAMA Netw Open. 2019;2(9):e1911421. doi:10.1001/jamanetworkopen.2019.11421
PEDIATRICS
Joan L. Luby, MD; Rebecca Tillman, MS; Deanna M. Barch, PhD
This cohort study assesses the timing and regional specificity of the association of adverse childhood experiences and caregiver support with structural development of limbic and striatal brain regions in middle childhood and adolescence.
JAMA Netw Open. 2019;2(9):e1911426. doi:10.1001/jamanetworkopen.2019.11426
HEALTH POLICY
Taressa K. Fraze, PhD; Amanda L. Brewster, PhD; Valerie A. Lewis, PhD; et al.
This cross-sectional study uses national survey data to assess the percentage of US hospitals and physician practices that screen patients for food insecurity, housing instability, utility needs, transportation needs, and interpersonal violence and to compare characteristics between screening and nonscreening entities.
JAMA Netw Open. 2019;2(9):e1911514. doi:10.1001/jamanetworkopen.2019.11514
ONCOLOGY
David Hsiehchen, MD; Mary K. Watters, MD; Rong Lu, PhD; et al.
This cross-sectional study assesses the concordance of algorithm-driven medical record review by medical oncologists for the characterization of 8 immune-related adverse events in patients with cancer treated with immune checkpoint inhibitors.
JAMA Netw Open. 2019;2(9):e1911519. doi:10.1001/jamanetworkopen.2019.11519
HEALTH INFORMATICS
Mina S. Sedrak, MD, MS; Virginia Sun, RN, PhD; Jennifer Liu, BS; et al.
This qualitative study examines physician attitudes toward and perceptions of social media use for therapeutic trial recruitment of patients with cancer.
JAMA Netw Open. 2019;2(9):e1911528. doi:10.1001/jamanetworkopen.2019.11528
PEDIATRICS
Abby R. Rosenberg, MD, MS, MA; Miranda C. Bradford, MS; Courtney C. Junkins, PsyD; et al.
This phase 2 randomized clinical trial compares the effects of individual- or group-based delivery of the novel intervention Promoting Resilience in Stress Management for Parents (PRISM-P) with the effects of usual care on improved self-reported resilience among parents of children receiving a new diagnosis of cancer.
JAMA Netw Open. 2019;2(9):e1911578. doi:10.1001/jamanetworkopen.2019.11578
PHARMACY AND CLINICAL PHARMACOLOGY
Andrea L. Schaffer, MSc, MBiostat, PhD; Nicholas A. Buckley, MD; Rose Cairns, PhD; et al.
This interrupted time series analysis and cross-sectional study examines changes in alprazolam prescribing patterns after a national policy change that reduced alprazolam subsidies in Australia.
JAMA Netw Open. 2019;2(9):e1911590. doi:10.1001/jamanetworkopen.2019.11590
UROLOGY
Joseph D. Shirk, MD; David D. Thiel, MD; Eric M. Wallen, MD; et al.
This single-blind randomized clinical trial examines whether 3-dimensional (3-D) virtual reality models used to plan robotic-assisted partial nephrectomy can reduce the operative time, estimated blood loss, clamp time, and length of hospital stay.
JAMA Netw Open. 2019;2(9):e1911598. doi:10.1001/jamanetworkopen.2019.11598
ONCOLOGY
Tomasz Burzykowski, PhD; Elisabeth Coart, PhD; Everardo D. Saad, MD; et al.
This study examines the use of time to nadir and depth of nadir as surrogate end points for overall survival in phase 3 randomized clinical trials evaluating first-line treatment in patients with metastatic colorectal cancer.
JAMA Netw Open. 2019;2(9):e1911750. doi:10.1001/jamanetworkopen.2019.11750
CARDIOLOGY
Husam Abdel-Qadir, MD, PhD; Paaladinesh Thavendiranathan, MD, MSc; Kinwah Fung, MSc; et al.
This matched cohort study investigates whether early-stage breast cancer and subsequent chemotherapy are associated with the risk of developing atrial fibrillation among women in Ontario, Canada, who were diagnosed with early-stage breast cancer compared with women without breast cancer.
JAMA Netw Open. 2019;2(9):e1911838. doi:10.1001/jamanetworkopen.2019.11838
ONCOLOGY
Yu Chen, MD, PhD; Gang Chen, MD; Jin Li, PhD; et al.
This cohort study examines the association of comutation of tumor protein p53 (TP53) and ataxia-telangiectasia mutated (ATM) genes with response to immune checkpoint inhibitor (ICI) treatment and overall survival among patients with non鈥搒mall cell lung cancer (NSCLC).
JAMA Netw Open. 2019;2(9):e1911895. doi:10.1001/jamanetworkopen.2019.11895
SUBSTANCE USE AND ADDICTION
Hongying Dai, PhD; Kimber P. Richter, PhD
This survey study analyzes the prevalence and patterns of marijuana use among adults with and without medical conditions using data from the 2016 and 2017 Behavioral Risk Factor Surveillance System surveys.
has audio
JAMA Netw Open. 2019;2(9):e1911936. doi:10.1001/jamanetworkopen.2019.11936
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Podcast:
Effect of Electronic Medication Reconciliation on Adverse Events, and Marijuana Use Patterns in Adults
PSYCHIATRY
Katherine A. Kaplan, PhD; Meital Mashash, BA; Rayma Williams, BS; et al.
This randomized clinical trial examines whether a novel intervention, using both light exposure during sleep and cognitive behavioral therapy, increases total sleep time in teenagers by enabling them to go to sleep earlier than usual.
JAMA Netw Open. 2019;2(9):e1911944. doi:10.1001/jamanetworkopen.2019.11944
ONCOLOGY
Steven D. Criss, BS; Meghan J. Mooradian, MD; Tina R. Watson, BA; et al.
This economic evaluation examines whether atezolizumab plus bevacizumab, carboplatin, and paclitaxel is cost-effective vs bevacizumab, carboplatin, and paclitaxel alone as a first-line treatment for US patients with metastatic nonsquamous non鈥搒mall cell lung cancer (NSCLC).
JAMA Netw Open. 2019;2(9):e1911952. doi:10.1001/jamanetworkopen.2019.11952
ONCOLOGY
Wei Jie Seow, ScD; Xiao-Ou Shu, PhD; Jeremy K. Nicholson, PhD; et al.
This case-control study investigates the association between urinary metabolomic biomarkers and lung cancer risk among never-smoking women in China.
JAMA Netw Open. 2019;2(9):e1911970. doi:10.1001/jamanetworkopen.2019.11970
ONCOLOGY
Nicholas T. Usher; Suyoung Chang, MD; Robin S. Howard, MA; et al.
This 60-year follow-up of a clinical trial investigates the association between BCG vaccination during childhood and diagnosis with cancer in adulthood.
JAMA Netw Open. 2019;2(9):e1912014. doi:10.1001/jamanetworkopen.2019.12014
DIABETES AND ENDOCRINOLOGY
Eric M. Schmidt, PhD; James Barnes, MD, MS; Cheng Chen, MS; et al.
This cohort study uses data from the US Veterans Affairs health care systems to examine whether preexisting mental health or substance use disorders and primary care utilization before a new diabetes diagnosis are associated with the long-term severity of diabetes complications.
JAMA Netw Open. 2019;2(9):e1912060. doi:10.1001/jamanetworkopen.2019.12060
SURGERY
Florian Roquet, MD; Arthur Neuschwander, MD; Sophie Hamada, MD; et al.
This cohort study analyzes data from the French national trauma registry Traumabase to examine whether an early, high ratio of fresh frozen plasma to packed red blood cells is associated with all-cause 30-day mortality in adults with severe bleeding after trauma.
JAMA Netw Open. 2019;2(9):e1912076. doi:10.1001/jamanetworkopen.2019.12076
GERIATRICS
Risha Gidwani-Marszowski, DrPH; Steven M. Asch, MD, MPH; Vincent Mor, PhD; et al.
To provide physicians with reference cost estimates, this cohort study quantifies beneficiary and health system costs incurred in association with receipt of intensive medical services in the last month of life among patients with advanced cancer.
JAMA Netw Open. 2019;2(9):e1912161. doi:10.1001/jamanetworkopen.2019.12161
CARDIOLOGY
Alan Rozanski, MD; Chirag Bavishi, MD, MPH; Laura D. Kubzansky, PhD; et al.
This meta-analysis assesses whether individuals with a mindset of optimism have a lower risk of cardiovascular events and all-cause mortality.
has expired quiz
JAMA Netw Open. 2019;2(9):e1912200. doi:10.1001/jamanetworkopen.2019.12200
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Invited Commentary
Optimism and Health: Where Do We Go From Here?
Jeff C. Huffman, MD
JAMA Netw Open
PEDIATRICS
Daniel C. Payne, PhD, MSPH; Janet A. Englund, MD; Geoffrey A. Weinberg, MD; et al.
This case-control study assesses US vaccine effectiveness for 2 rotavirus vaccines in preventing rotavirus inpatient and emergency department visits among children younger than 5 years.
JAMA Netw Open. 2019;2(9):e1912242. doi:10.1001/jamanetworkopen.2019.12242
ONCOLOGY
Paul M. Cinciripini, PhD; Maher Karam-Hage, MD; George Kypriotakis, PhD; et al.
This cohort analysis examines the use of a tobacco treatment program for patients with cancer who continue to smoke after diagnosis.
JAMA Netw Open. 2019;2(9):e1912251. doi:10.1001/jamanetworkopen.2019.12251
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Invited Commentary
Effective Cessation Treatment for Patients With Cancer Who Smoke鈥擳he Fourth Pillar of Cancer Care
Michael C. Fiore, MD, MPH, MBA; Heather D鈥橝ngelo, MHS, PhD; Timothy Baker, PhD
JAMA Netw Open
ONCOLOGY
Gordon P. Watt, PhD; Anne S. Reiner, MPH; Susan A. Smith, MPH; et al.
This case-control study assesses the association of a genetic risk score based on variants in a DNA repair pathway with risk of a second primary contralateral breast cancer after radiation therapy for a first breast cancer.
JAMA Netw Open. 2019;2(9):e1912259. doi:10.1001/jamanetworkopen.2019.12259
HEALTH POLICY
Joshua M. Liao, MD, MSc; Ezekiel J. Emanuel, MD, PhD; Atheendar S. Venkataramani, MD, PhD; et al.
This cohort study examines the association between coparticipation in voluntary accountable care organizations (ACOs) and hospital performance on lower-extremity joint replacement outcomes and spending.
JAMA Netw Open. 2019;2(9):e1912270. doi:10.1001/jamanetworkopen.2019.12270
ONCOLOGY
Xue Xu, PhD; Jianqiang Li, PhD; Jinfeng Zou, PhD; et al.
This genetic association study examines whether germline variants of natural killer cells are associated with tumor immune microenvironment subtypes, the abundance of tumor-infiltrating lymphocytes, response to immune checkpoint therapy, clinical outcomes, and cancer risk.
JAMA Netw Open. 2019;2(9):e199292. doi:10.1001/jamanetworkopen.2019.9292
INFECTIOUS DISEASES
James H. Ford II, PhD; Lillian Vranas, MS; DaRae Coughlin, RN, MSN, FNP-BC; et al.
This trial protocol describes a randomized clinical trial intended to compare 2 strategies for implementing a toolkit for enhancing recognition and management of urinary tract infections in nursing homes.
JAMA Netw Open. 2019;2(9):e199526. doi:10.1001/jamanetworkopen.2019.9526
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Invited Commentary
Taking a Ride on the Stewardship Side of Long-term Care: The Cadillac and the Camry
Barbara W. Trautner, MD, PhD; Aanand D. Naik, MD
JAMA Netw Open
NEUROLOGY
Lara M. C. Puhlmann, MSc; Sofie L. Valk, PhD; Veronika Engert, PhD; et al.
This randomized clinical trial examines the effect of mental attention training on leukocyte telomere length and cortical thickness among healthy adults.
JAMA Netw Open. 2019;2(9):e199687. doi:10.1001/jamanetworkopen.2019.9687
OCCUPATIONAL HEALTH
Hillel W. Cohen, DrPH, MPH; Rachel Zeig-Owens, DrPH, MPH; Cynthia Joe, MPH; et al.
This cohort study examines the long-term risk for the development of cardiovascular disease in firefighters who responded to the World Trade Center disaster on September 11, 2001, and worked at the site thereafter.
JAMA Netw Open. 2019;2(9):e199775. doi:10.1001/jamanetworkopen.2019.9775