SURGERY
Andrew C. Qi, BS; Kate Peacock, MPH; Alina A. Luke, MPH; et al.
This cross-sectional study examines whether social risk factors, including race/ethnicity, insurance status, and neighborhood income, are associated with higher rates of surgical site infection after colectomy or abdominal hysterectomy.
JAMA Netw Open. 2019;2(10):e1912339. doi:10.1001/jamanetworkopen.2019.12339
ENVIRONMENTAL HEALTH
Guoying Wang, MD, PhD; Jessica DiBari, PhD; Eric Bind, MPP; et al.
This cohort study investigates the associations between maternal red blood cell lead levels and intergenerational risk of overweight or obesity and whether adequate maternal folate status is associated with a reduction in this risk.
JAMA Netw Open. 2019;2(10):e1912343. doi:10.1001/jamanetworkopen.2019.12343
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Invited Commentary
Adequate Prenatal Maternal Folate鈥擜n Additional Intervention Strategy Among Populations Affected by Prenatal Lead Exposure?
Marco Sanchez-Guerra, PhD, MSc; Andres Cardenas, PhD, MPH; Citlalli Osorio-Yáñez, PhD, MSc
JAMA Netw Open
GERIATRICS
Amal A. Wanigatunga, PhD, MPH; Junrui Di, PhD; Vadim Zipunnikov, PhD; et al.
This cohort study of adults aged 65 years and older examines whether more fragmentated physical activity, rather than total daily activity, is associated with increased mortality risk.
JAMA Netw Open. 2019;2(10):e1912352. doi:10.1001/jamanetworkopen.2019.12352
PHYSICAL MEDICINE AND REHABILITATION
Emily Somerville, OTD, OTR/L; Brittany Minor, MS, OTR/L; Marian Keglovits, MSci, OTD, OTR/L; et al.
This trial protocol describes a randomized clinical trial that will investigate the efficacy and safety of a novel enhanced rehabilitation program to reduce environmental barriers and improve daily activity performance and community participation among stroke survivors.
JAMA Netw Open. 2019;2(10):e1912356. doi:10.1001/jamanetworkopen.2019.12356
SURGERY
Victor H. Hatcher, MHS; Colette Galet, PhD; Michele Lilienthal, RN, MA; et al.
This cohort study assesses whether clinical frailty scores are associated with readmission for falls after index admission for trauma-related injury among patients aged 50 years and older.
JAMA Netw Open. 2019;2(10):e1912409. doi:10.1001/jamanetworkopen.2019.12409
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Invited Commentary
Predicting Readmissions鈥擶ith a Twist
Lillian Min, MD, MSHS; Geoffrey J. Hoffman, PhD
JAMA Netw Open
ONCOLOGY
Nathan D. Seligson, PharmD; Achal Awasthi, MS; Sherri Z. Millis, PhD; et al.
This cross-sectional study characterizes secondary genomic alterations in patients with epithelioid hemangioendothelioma and their association with clinical outcomes.
JAMA Netw Open. 2019;2(10):e1912416. doi:10.1001/jamanetworkopen.2019.12416
DIABETES AND ENDOCRINOLOGY
Anna S. Frank, MSc; Angela Lupattelli, PhD; Ragnhild E. Brandlistuen, PhD; et al.
This population-based cohort study examines associations between prenatal thyroid hormone replacement therapy exposure and risk of language impairment and parent-reported symptoms of language and communication skill deficits in offspring at 8 years of age.
JAMA Netw Open. 2019;2(10):e1912424. doi:10.1001/jamanetworkopen.2019.12424
HEALTH POLICY
Luke J. DeRoos, MS; Wesley J. Marrero, MS; Elliot B. Tapper, MD; et al.
This decision analytical model study uses a simulation model to evaluate the potential implications of a presumed consent policy for deceased organ donation allocation and availability in the United States.
JAMA Netw Open. 2019;2(10):e1912431. doi:10.1001/jamanetworkopen.2019.12431
PUBLIC HEALTH
Rebecca Chen, BA; J. Aaron Hipp, PhD; Lily Morrison, MPH; et al.
This cross-sectional study investigates whether indoor tanning salons are disproportionately located in areas with higher concentrations of sexual-minority men, defined as gay and bisexual men, using male-male partnered households as a proxy measure.
JAMA Netw Open. 2019;2(10):e1912443. doi:10.1001/jamanetworkopen.2019.12443
INFECTIOUS DISEASES
Hai-Ling Lu, MD; Ying Ding, MD, PhD; Hemant Goyal, MD; et al.
This systematic review and meta-analysis assesses the association of rotavirus vaccination among neonates and infants with risk of intussusception for up to 2 years after vaccination overall and by type of vaccine.
JAMA Netw Open. 2019;2(10):e1912458. doi:10.1001/jamanetworkopen.2019.12458
OBSTETRICS AND GYNECOLOGY
Charlotte Skoglund, PhD; Helena Kopp Kallner, PhD; Alkistis Skalkidou, PhD; et al.
This cohort study examines the association of attention-deficit/hyperactivity disorder (ADHD) with teenage pregnancy among women and girls in Sweden.
JAMA Netw Open. 2019;2(10):e1912463. doi:10.1001/jamanetworkopen.2019.12463
PUBLIC HEALTH
Lauren Brinkley-Rubinstein, PhD; Josie Sivaraman, MSPH; David L. Rosen, PhD, MD; et al.
This cohort study evaluates whether restrictive housing, otherwise known as solitary confinement, during incarceration is associated with reincarceration and mortality after release.
JAMA Netw Open. 2019;2(10):e1912516. doi:10.1001/jamanetworkopen.2019.12516
GASTROENTEROLOGY AND HEPATOLOGY
David E. Kleiner, MD; Elizabeth M. Brunt, MD; Laura A. Wilson, ScM; et al.
This cohort study evaluates the progression and regression of hepatic fibrosis over time in association with the severity of nonalcoholic fatty liver disease.
JAMA Netw Open. 2019;2(10):e1912565. doi:10.1001/jamanetworkopen.2019.12565
ONCOLOGY
Michael W. Piepkorn, MD, PhD; Gary M. Longton, MS; Lisa M. Reisch, PhD; et al.
This diagnostic study evaluates whether fellowship training and board certification of physicians in dermatopathology affect the diagnostic reliability of second-opinion strategies for difficult-to-diagnose cutaneous melanocytic lesions.
JAMA Netw Open. 2019;2(10):e1912597. doi:10.1001/jamanetworkopen.2019.12597
PEDIATRICS
Rachel Caskey, MD, MAPP; Kellyn Moran, PharmD; Daniel Touchette, PharmD; et al.
This randomized clinical trial assesses whether a comprehensive care coordination program reduces Medicaid expenditures by decreasing hospital and emergency department utilization among publicly insured children and youth.
JAMA Netw Open. 2019;2(10):e1912604. doi:10.1001/jamanetworkopen.2019.12604
OBSTETRICS AND GYNECOLOGY
Ngaire H. Anderson, PhD; Adrienne Gordon, PhD; Minglan Li, PhD; et al.
This prespecified subgroup analysis of control participants in an individual participant data meta-analysis examines the association between supine vs nonsupine maternal sleeping position in the third trimester of pregnancy and infant birth weight.
JAMA Netw Open. 2019;2(10):e1912614. doi:10.1001/jamanetworkopen.2019.12614
HEALTH INFORMATICS
Daniel R. Murphy, MD, MBA; Traber D. Giardina, MSW, PhD; Tyler Satterly, MEng; et al.
This qualitative analysis using interviews with physicians determines barriers and facilitators in electronic health record inbox management and suggestions for improvement.
JAMA Netw Open. 2019;2(10):e1912638. doi:10.1001/jamanetworkopen.2019.12638
STATISTICS AND RESEARCH METHODS
Natalia Blanco, PhD, MPH; Anthony D. Harris, MD, MPH; Laurence S. Magder, PhD, MPH; et al.
This study of national rates of health care鈥揳ssociated infections estimates the number of hospitals needed to power parallel cluster-randomized trials of interventions and evaluates how different parameters such as coefficient of variation and expected effect size are associated with the sample size estimates in practice.
JAMA Netw Open. 2019;2(10):e1912644. doi:10.1001/jamanetworkopen.2019.12644
HEMATOLOGY
Dawn Maze, MD, FRCPC, MSc; Sajida Kazi, MBBS, FRCPath, MRCP; Vikas Gupta, MD, FRCP, FRCPath; et al.
This systematic review and meta-analysis examines whether the use of aspirin, heparin, and interferon in pregnant women with myeloproliferative neoplasms is associated with live birth rate and adverse maternal outcomes.
JAMA Netw Open. 2019;2(10):e1912666. doi:10.1001/jamanetworkopen.2019.12666
PEDIATRICS
Jincheng Feng, MD; Ying He, MD; Lai Wei, MD; et al.
This cohort study uses Surveillance, Epidemiology, and End Results data to examine whether there is a survival benefit associated with liver transplant vs resection in pediatric patients with hepatoblastoma receiving chemotherapy.
JAMA Netw Open. 2019;2(10):e1912676. doi:10.1001/jamanetworkopen.2019.12676
HEALTH POLICY
Nathaniel Bell, PhD; Ana Lòpez-De Fede, PhD; Bo Cai, PhD; et al.
This cross-sectional study uses data from the New York State Health Cost and Utilization Project State Inpatient Database to examine whether the reliability of American Community Survey socioeconomic status estimates improves with the use of new peer group鈥揵ased strata compared with previous stratification by safety-net hospital designation.
JAMA Netw Open. 2019;2(10):e1912727. doi:10.1001/jamanetworkopen.2019.12727
NEUROLOGY
Romina Mariano, MBBCh; Silvia Messina, MD; Kurun Kumar, BM BCh; et al.
This cross-sectional study examines clinical and radiological outcomes among patients with myelin oligodendrocyte glycoprotein (MOG) antibody (Ab) disease or aquaporin-4 (AQP4)-Ab disease after experiencing a first transverse myelitis episode.
JAMA Netw Open. 2019;2(10):e1912732. doi:10.1001/jamanetworkopen.2019.12732
ONCOLOGY
Robert C. Grant, MD, MA; Rahim Moineddin, PhD; Zhan Yao, MSc; et al.
This cohort study uses population-based administrative and clinical databases to develop and validate a score to predict early use of acute care after initiating systemic therapy for cancer.
JAMA Netw Open. 2019;2(10):e1912823. doi:10.1001/jamanetworkopen.2019.12823
CARDIOLOGY
Charalambos Vlachopoulos, MD; Dimitrios Terentes-Printzios, MD; Stephane Laurent, MD, PhD; et al.
This secondary analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) investigates whether aortic stiffness, as assessed by estimated pulse wave velocity, and its response to treatment are associated with survival in individuals with hypertension.
JAMA Netw Open. 2019;2(10):e1912831. doi:10.1001/jamanetworkopen.2019.12831
PUBLIC HEALTH
Ashley E. Wolf, MD; Michelle M. Garrison, PhD, MPH; Brianna Mills, MA, PhD; et al.
This cohort study compares the resource utilization, clinical outcomes, and severity of injuries from a firearm vs other penetrating mechanisms among children and adolescents in the United States.
JAMA Netw Open. 2019;2(10):e1912850. doi:10.1001/jamanetworkopen.2019.12850
STATISTICS AND RESEARCH METHODS
Victoria L. Bartlett, BA; Sanket S. Dhruva, MD, MHS; Nilay D. Shah, PhD; et al.
This cross-sectional study analyzes the feasibility of replicating clinical trials by examining whether the interventions, indications, inclusion and exclusion criteria, and primary end points could be ascertained from observational data from insurance claims and/or electronic health records (EHRs).
JAMA Netw Open. 2019;2(10):e1912869. doi:10.1001/jamanetworkopen.2019.12869
PUBLIC HEALTH
Alexander Hodkinson, PhD; Evangelos Kontopantelis, PhD; Charles Adeniji, MD; et al.
This systematic review and meta-analysis examines the association of accelerometer- and pedometer-based interventions with increases in physical activity among participants with cardiometabolic conditions.
JAMA Netw Open. 2019;2(10):e1912895. doi:10.1001/jamanetworkopen.2019.12895
ENVIRONMENTAL HEALTH
Akhgar Ghassabian, MD; Livia Pierotti, MSc; Mikel Basterrechea, PhD; et al.
This cohort study evaluates the short-term association of exposure to air pollution in the first trimester with thyroid function throughout pregnancy among European and US cohorts.
JAMA Netw Open. 2019;2(10):e1912902. doi:10.1001/jamanetworkopen.2019.12902
PSYCHIATRY
Zachary J. Ward, MPH; Patricia Rodriguez, MPH; Davene R. Wright, PhD; et al.
This decision analytical model study uses a virtual cohort of 100鈥�000 individuals modeled from birth to age 40 years for 4 eating disorder diagnoses to examine whether increasing treatment coverage could reduce the mortality associated with eating disorders.
JAMA Netw Open. 2019;2(10):e1912925. doi:10.1001/jamanetworkopen.2019.12925
SURGERY
Jessica I. Billig, MD, MS; Kelly A. Speth, MS; Jacob S. Nasser, BS; et al.
This population-based cohort study examines treatment patterns for stenosing tenosynovitis (trigger finger) and determines surgeon-level factors associated with adherence to evidence-based treatment.
JAMA Netw Open. 2019;2(10):e1912960. doi:10.1001/jamanetworkopen.2019.12960
PUBLIC HEALTH
Shannon B. Juengst, PhD, CRC; Alexa Royston, DO; Isabel Huang, MD; et al.
This cross-sectional US nationwide survey study assesses the negative and positive aspects of family leave and return-to-work experiences among physician mothers to identify best practices for supporting physician parents.
JAMA Netw Open. 2019;2(10):e1913054. doi:10.1001/jamanetworkopen.2019.13054
CARDIOLOGY
Vinay Kini, MD, MSHP; Timea Viragh, MA; David Magid, MD, MPH; et al.
This cohort study assesses whether changes in overall rates of use of diagnostic cardiovascular tests were associated with changes in high-value testing recommended by guidelines and low-value testing that is expected to provide minimal benefits among a 5% national sample of Medicare beneficiaries between 2000 and 2006.
JAMA Netw Open. 2019;2(10):e1913070. doi:10.1001/jamanetworkopen.2019.13070
RHEUMATOLOGY
Jawad Bilal, MD; Adam Berlinberg, MD; Irbaz Bin Riaz, MD, MS; et al.
This systematic review and meta-analysis examines the risk for serious infections, opportunistic infections, and cancers in individuals receiving interleukin inhibitor therapies for rheumatologic diseases.
JAMA Netw Open. 2019;2(10):e1913102. doi:10.1001/jamanetworkopen.2019.13102
NEPHROLOGY
Claire A. Richards, PhD, RN; Paul L. Hebert, PhD; Chuan-Fen Liu, PhD, MPH; et al.
This survey study examines the association of family-rated quality of end-of-life care with stopping dialysis treatment and receipt of hospice services among veterans with end-stage renal disease.
JAMA Netw Open. 2019;2(10):e1913115. doi:10.1001/jamanetworkopen.2019.13115
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Invited Commentary
Stopping Dialysis, Good Deaths, and Social Justice
Channing E. Tate, MPH; Daniel D. Matlock, MD, MPH
JAMA Netw Open
NEUROLOGY
Line Jee Hartmann Rasmussen, PhD; Avshalom Caspi, PhD; Antony Ambler, MSc; et al.
This 5-decade cohort study of a New Zealand population examines whether slow gait speed in middle age is associated with accelerated biological aging, as well as poor neurocognitive functioning in childhood and cognitive decline from childhood to middle age.
JAMA Netw Open. 2019;2(10):e1913123. doi:10.1001/jamanetworkopen.2019.13123
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Invited Commentary
Gait Speed Reveals Clues to Lifelong Health
Stephanie Studenski, MD, MPH
JAMA Netw Open
CARDIOLOGY
Liyuan Han, PhD; Dingyun You, PhD; Wenjie Ma, PhD; et al.
This cross-sectional study examines the association of adherence to the American Heart Association (AHA) revised Life鈥檚 Simple 7 (LS7) metrics with reduced risk of all-cause, cancer, and cardiovascular disease鈥搑elated mortality and compares the revised metrics with the original LS7 metrics.
JAMA Netw Open. 2019;2(10):e1913131. doi:10.1001/jamanetworkopen.2019.13131
DIABETES AND ENDOCRINOLOGY
Rene Rodriguez-Gutierrez, MD, MSc; Jeph Herrin, PhD; Kasia J. Lipska, MD, MHS; et al.
This cohort study examines racial/ethnic differences in all-cause readmission among US adults with diabetes and categorizes patient- and system-level factors associated with these differences.
JAMA Netw Open. 2019;2(10):e1913249. doi:10.1001/jamanetworkopen.2019.13249
EMERGENCY MEDICINE
Peter A. Kahn, MD, MPH, ThM; Sanket S. Dhruva, MD, MHS; Taeho Greg Rhee, PhD, MSW; et al.
This cross-sectional study uses data from the National Emergency Medical Services Information System to investigate the use of mechanical cardiopulmonary resuscitation (CPR) in the prehospital setting and determine whether patient demographics or geographical location is associated with its use.
JAMA Netw Open. 2019;2(10):e1913298. doi:10.1001/jamanetworkopen.2019.13298
PSYCHIATRY
Muhammad Mamdani, PharmD, MA, MPH; Tara Gomes, MHSc, PhD; Simon Greaves, MSc; et al.
This population-based case-control study of individuals aged 66 years and older in Ontario, Canada, examines whether angiotensin receptor blockers are associated with a higher risk of suicide than angiotensin-converting enzyme inhibitors.
JAMA Netw Open. 2019;2(10):e1913304. doi:10.1001/jamanetworkopen.2019.13304
HEALTH POLICY
Ishani Ganguli, MD, MPH; Arabella L. Simpkin, MD, MMSc; Claire Lupo, BBA; et al.
This survey study estimates the national frequency and consequences of cascades of care after incidental findings using results from a national survey of US physicians.
JAMA Netw Open. 2019;2(10):e1913325. doi:10.1001/jamanetworkopen.2019.13325
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Invited Commentary
The Important but Rarely Studied Cascade of Care
John Mandrola, MD; Daniel J. Morgan, MD, MS
JAMA Netw Open
GERIATRICS
Yanxia Lu, PhD; Mathew Niti, PhD; Keng Bee Yap, MMed (Internal Med), MRCP (UK); et al.
This secondary analysis of a randomized clinical trial examines the association of a 6-month multidomain active lifestyle intervention with sarcopenia among elderly participants in Singapore.
JAMA Netw Open. 2019;2(10):e1913346. doi:10.1001/jamanetworkopen.2019.13346
NEUROLOGY
Jason C. You, MD, PhD; Erica Jones, BS; Devon E. Cross, BS, BA; et al.
This survey study examines whether 尾-amyloid deposition in the brain is associated with sleep dysfunction and cognition in elderly individuals with cognitive disorders.
JAMA Netw Open. 2019;2(10):e1913383. doi:10.1001/jamanetworkopen.2019.13383
OBSTETRICS AND GYNECOLOGY
Rabel Misbah Rameez, MD; Divyajot Sadana, MD; Simrat Kaur, MD; et al.
This systematic review and meta-analysis examines the association between breastfeeding and maternal risk of diabetes and hypertension.
JAMA Netw Open. 2019;2(10):e1913401. doi:10.1001/jamanetworkopen.2019.13401
DERMATOLOGY
Michael Phillips, MMedSci; Helen Marsden, PhD; Wayne Jaffe, MB, ChB, FRCS; et al.
This diagnostic study determines the accuracy of an artificial intelligence algorithm in identifying melanoma in dermoscopic images of lesions taken with smartphone and digital single-lens reflex (DSLR) cameras.
JAMA Netw Open. 2019;2(10):e1913436. doi:10.1001/jamanetworkopen.2019.13436
NEUROLOGY
Gregory S. Day, MD, MSc; Carlos Cruchaga, PhD; Thomas Wingo, MD; et al.
This cohort study examines the associations of acquired and heritable factors associated with intergenerational differences in age at symptomatic onset of Alzheimer disease among offspring of parents with Alzheimer disease.
JAMA Netw Open. 2019;2(10):e1913491. doi:10.1001/jamanetworkopen.2019.13491
HEALTH POLICY
Michelle Ko, MD, PhD; Armin Dorri, BA, BS
This qualitative study describes the professional experiences and the perceived associations with gender, race/ethnicity, sexual orientation, and gender identity of a diverse group of primary care clinicians and clinic directors in an underserved rural and agricultural region of California.
JAMA Netw Open. 2019;2(10):e1913535. doi:10.1001/jamanetworkopen.2019.13535
CARDIOLOGY
Ryan T. Borne, MD; Tiffany Randolph, MD; Yongfei Wang, MS; et al.
This cross-sectional study examines temporal trends and variations in the use of defibrillation testing among patients undergoing first-time implantable cardioverter-defibrillator implantation.
JAMA Netw Open. 2019;2(10):e1913553. doi:10.1001/jamanetworkopen.2019.13553
OCCUPATIONAL HEALTH
Orianne Dumas, PhD; Raphaëlle Varraso, PhD; Krislyn M. Boggs, MPH; et al.
This cohort study evaluates data from the Nurses鈥� Health Study II to investigate the association of occupational exposure to disinfectants and other cleaning products with the incidence of chronic obstructive pulmonary disease (COPD) among female US registered nurses with no history of COPD at baseline.
has audio
JAMA Netw Open. 2019;2(10):e1913563. doi:10.1001/jamanetworkopen.2019.13563
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Podcast:
Disinfectant Exposure and COPD Among Nurses; Pediatric Socioeconomic Status and Associated Hospital Efficiency and Costs
INFECTIOUS DISEASES
Daniel A. Caroff, MD, MPH; Christina Chan, MPH; Ken Kleinman, ScD; et al.
This cohort study compares the surgical site infection rate associated with laparoscopic colon surgery vs open-approach laparoscopy.
JAMA Netw Open. 2019;2(10):e1913570. doi:10.1001/jamanetworkopen.2019.13570
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Invited Commentary
Learning Curves and the Challenges of Adopting New Surgical Techniques
Laura A. Graham, PhD, MPH; Mary T. Hawn, MD, MPH
JAMA Netw Open
CARDIOLOGY
Kelvin N. V. Bush, MD; Julie L. Teel, FNP; James A. Watts, MD; et al.
This cohort study examines endothelial function in patients with early HIV infection at baseline and after antiretroviral therapy initiation.
JAMA Netw Open. 2019;2(10):e1913615. doi:10.1001/jamanetworkopen.2019.13615
ONCOLOGY
Bin Zhang, PhD; Min Min Li, MD; Wen Hui Chen, PhD; et al.
This systematic review and meta-analysis assesses whether concurrent chemoradiotherapy is associated with improvement in survival outcomes for patients with locoregionally advanced nasopharyngeal carcinoma.
JAMA Netw Open. 2019;2(10):e1913619. doi:10.1001/jamanetworkopen.2019.13619
GLOBAL HEALTH
Eleanor Frances Georgina Neal, MPH; Cattram Nguyen, PhD; Felista Tupou Ratu, BPHN; et al.
This cross-sectional study uses surveys to describe and compare pneumococcal nasopharyngeal carriage and density by vaginal vs cesarean delivery in young Fijian infants.
JAMA Netw Open. 2019;2(10):e1913650. doi:10.1001/jamanetworkopen.2019.13650
HEALTH POLICY
Morgane Michel, MD; Corinne Alberti, PhD; Jean-Claude Carel, PhD; et al.
This cohort study examines the association of pediatric inpatient socioeconomic status with the hospital鈥檚 efficiency and financial balance in France.
has audio
JAMA Netw Open. 2019;2(10):e1913656. doi:10.1001/jamanetworkopen.2019.13656
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Podcast:
Disinfectant Exposure and COPD Among Nurses; Pediatric Socioeconomic Status and Associated Hospital Efficiency and Costs
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Invited Commentary
Adjusting Hospital Reimbursement to Account for Social Influences on Health
Matthew M. Davis, MD, MAPP; Kristin Kan, MD, MPH, MSc
JAMA Netw Open
Abstract
Full Text
pdf link PDF
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Podcast:
Disinfectant Exposure and COPD Among Nurses; Pediatric Socioeconomic Status and Associated Hospital Efficiency and Costs
INFECTIOUS DISEASES
Wenjing Ji, PhD; Caroline McKenna, MPH; Aileen Ochoa, MPH; et al.
This cohort study develops and assesses electronic surveillance definitions for nonventilator hospital-acquired pneumonia using clinical data routinely recorded in electronic health records.
JAMA Netw Open. 2019;2(10):e1913674. doi:10.1001/jamanetworkopen.2019.13674
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Invited Commentary
Working Toward Better Metrics for Nonventilator Hospital-Acquired Pneumonia
Jonathan Baghdadi, MD; Anthony D. Harris, MD, MPH
JAMA Netw Open
MEDICAL JOURNALS AND PUBLISHING
Emma G. Thomas, MSc, MA; Bamini Jayabalasingham, PhD; Tom Collins, PhD; et al.
This case-control study examines gender differences in authorship of invited commentaries published in medical journals from 2013 to 2017, controlling for field of expertise, seniority, and publication metrics.
JAMA Netw Open. 2019;2(10):e1913682. doi:10.1001/jamanetworkopen.2019.13682
NUTRITION, OBESITY, AND EXERCISE
Radhika V. Seimon, PhD; Anthony L. Wild-Taylor, BSc (Hons); Shelley E. Keating, PhD; et al.
This randomized clinical trial compares the long-term effects of weight loss via severe vs moderate energy restriction on lean mass and other aspects of body composition among postmenopausal women with obesity.
JAMA Netw Open. 2019;2(10):e1913733. doi:10.1001/jamanetworkopen.2019.13733
PUBLIC HEALTH
Andrea C. Villanti, PhD, MPH; Amanda L. Johnson, MHS; Allison M. Glasser, MPH; et al.
This cohort study uses data from the Population Assessment of Tobacco and Health (PATH) Study to examine whether first use of flavored tobacco products is associated with subsequent tobacco use among US youth and adults.
JAMA Netw Open. 2019;2(10):e1913804. doi:10.1001/jamanetworkopen.2019.13804
PSYCHIATRY
Kristina Aspvall, MSc; Erik Andersson, PhD; Fabian Lenhard, PhD; et al.
This protocol describes a randomized clinical noninferiority trial to determine whether cognitive behavioral therapy delivered online as part of a stepped care model is noninferior to, and cost-effective compared with, face-to-face cognitive behavioral therapy for pediatric obsessive-compulsive disorder (OCD).
JAMA Netw Open. 2019;2(10):e1913810. doi:10.1001/jamanetworkopen.2019.13810
SUBSTANCE USE AND ADDICTION
Brinton Clark, MD, MPH; Mari Kai, MD; Ryan Dix, PsyD; et al.
This quality improvement study examines the association of a multimodal educational intervention for primary care physicians (PCPs) with prescriptions of buprenorphine for treatment of patients with opioid use disorder.
JAMA Netw Open. 2019;2(10):e1913818. doi:10.1001/jamanetworkopen.2019.13818
INFECTIOUS DISEASES
Mark W. Vander Weg, PhD; Eli N. Perencevich, MD, MS; Amy M. J. O鈥橲hea, PhD; et al.
This cluster randomized trial investigates the effect of frequency of changing hand hygiene reminder signs on hand hygiene adherence among health care workers.
JAMA Netw Open. 2019;2(10):e1913823. doi:10.1001/jamanetworkopen.2019.13823
GENETICS AND GENOMICS
Rachid Karam, MD, PhD; Blair Conner, MS; Holly LaDuca, MS, GC; et al.
This diagnostic study evaluates whether RNA genetic testing (RGT) is associated with an improvement in the diagnostic outcome of DNA genetic testing (DGT) and in the delivery of personalized cancer risk management for patients with hereditary cancer predisposition.
JAMA Netw Open. 2019;2(10):e1913900. doi:10.1001/jamanetworkopen.2019.13900
NEUROLOGY
Vijay K Ramanan, MD, PhD; Anna M. Castillo, MS; David S. Knopman, MD; et al.
This cohort study investigates the association of the apolipoprotein E (APOE) 蓻4 allele, education levels, and sex with tau deposition and tau-mediated metabolic dysfunction in older adults.
JAMA Netw Open. 2019;2(10):e1913909. doi:10.1001/jamanetworkopen.2019.13909
ALLERGY
Marcus Shaker, MD, MSc; Dana Wallace, MD; David B. K. Golden, MD; et al.
This economic evaluation uses computer-simulated patients to examine the cost-effectiveness of short (1 hour) vs prolonged (鈮�6 hours) medical observation for biphasic anaphylaxis after an episode of resolved anaphylaxis.
JAMA Netw Open. 2019;2(10):e1913951. doi:10.1001/jamanetworkopen.2019.13951
GENETICS AND GENOMICS
Olena M. Vaske, PhD; Isabel Bjork, JD, MSc; Sofie R. Salama, PhD; et al.
This cohort study evaluates the feasibility and utility of incorporating comparative gene expression information into the precision medicine framework for difficult-to-treat pediatric and young adult patients with cancer.
JAMA Netw Open. 2019;2(10):e1913968. doi:10.1001/jamanetworkopen.2019.13968
COMPLEMENTARY AND ALTERNATIVE MEDICINE
Michelle Beidelschies, PhD; Marilyn Alejandro-Rodriguez, BSAS; Xinge Ji, MS; et al.
This cohort study uses the Patient-Reported Outcome Measurement Information System to assess the association between the functional medicine model of care and patient-reported health-related quality of life among adults.
JAMA Netw Open. 2019;2(10):e1914017. doi:10.1001/jamanetworkopen.2019.14017
NUTRITION, OBESITY, AND EXERCISE
Renying Xu, MD, PhD; Xiang Gao, MD, PhD; Yanping Wan, MD; et al.
This cohort study assesses the association of metabolically healthy overweight phenotype with the risk of glucose level abnormality and high blood pressure in Chinese adults.
JAMA Netw Open. 2019;2(10):e1914025. doi:10.1001/jamanetworkopen.2019.14025
PEDIATRICS
Nicolas F. Schlecht, PhD; Martin Masika, MD; Angela Diaz, MD, PhD; et al.
This cohort study assesses associations between sexual activity, the oral presence of human papillomavirus (HPV), and HPV vaccination among sexually active female adolescents vaccinated against 4 HPV types.
JAMA Netw Open. 2019;2(10):e1914031. doi:10.1001/jamanetworkopen.2019.14031
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Invited Commentary
Young Women and Oral Human Papillomavirus鈥擵accination Is Associated With Protection
Rachel A. Katzenellenbogen, MD; Kenneth H. Fife, MD, PhD
JAMA Netw Open
HEALTH INFORMATICS
Brett Beaulieu-Jones, PhD; Samuel G. Finlayson, MS; Corey Chivers, PhD; et al.
This qualitative study analyzes submissions to a popular machine learning for health workshop to assess the current state of health research, including areas of methodologic and clinical focus, limitations, and underexplored areas.
JAMA Netw Open. 2019;2(10):e1914051. doi:10.1001/jamanetworkopen.2019.14051
NEUROLOGY
Viviane Valdes, MPH; Carmen D. Zorrilla, MD; Laurel Gabard-Durnam, PhD; et al.
This cross-sectional study of 65 infants in Puerto Rico examines the associations of exposure to maternal Zika virus and Hurricane Maria with infant cognitive scores.
JAMA Netw Open. 2019;2(10):e1914061. doi:10.1001/jamanetworkopen.2019.14061
PEDIATRICS
Jordan E. DeVylder, PhD; Taylor C. Ryan, MS; Mary Cwik, PhD; et al.
This cohort study examines the association between results of universal and selective screening for suicide risk in a pediatric emergency department using the Ask Suicide-Screening Questions (ASQ) instrument and subsequent suicide-related outcomes.
JAMA Netw Open. 2019;2(10):e1914070. doi:10.1001/jamanetworkopen.2019.14070
PUBLIC HEALTH
Michael J. LaMonte, PhD, MPH; Jean Wactawski-Wende, PhD; Joseph C. Larson, MS; et al.
This cohort study of the Women鈥檚 Health Initiative (WHI) assesses the associations of physical activity and sedentary behavior with fracture incidence among postmenopausal women.
JAMA Netw Open. 2019;2(10):e1914084. doi:10.1001/jamanetworkopen.2019.14084
HEALTH POLICY
Rena M. Conti, PhD; Sayeh S. Nikpay, PhD, MPH; Melinda B. Buntin, PhD
This cross-sectional study reports revenues and estimated profits from the 340B drug discount program that hospitals collect from Medicare and Medicare beneficiaries for outpatient clinic administration of prescription drugs covered under Medicare Part B.
JAMA Netw Open. 2019;2(10):e1914141. doi:10.1001/jamanetworkopen.2019.14141
INFECTIOUS DISEASES
Nicholas A. Turner, MD, MHSc; Steven C. Grambow, PhD; Christopher W. Woods, MD, MPH; et al.
This cohort study examines the 5-year incidence of community-acquired and health care facility鈥揳ssociated Clostridioides difficile infection among patients in US community hospitals.
JAMA Netw Open. 2019;2(10):e1914149. doi:10.1001/jamanetworkopen.2019.14149
NEUROLOGY
Patricia Hafner, MD; Ulrike Bonati, MD; Andrea Klein, MD; et al.
This randomized clinical trial evaluates the effect of treatment with a combination of L-citrulline and metformin on the motor function of ambulant boys with Duchenne muscular dystrophy.
JAMA Netw Open. 2019;2(10):e1914171. doi:10.1001/jamanetworkopen.2019.14171
PUBLIC HEALTH
Emma Sartin, PhD, MPH; Tyler R. Bell, PhD; Catherine C. McDonald, PhD, RN; et al.
This systematic review and meta-analysis evaluates whether caregiver-targeted interventions are associated with changes in the use of child restraint systems in motor vehicles.
JAMA Netw Open. 2019;2(10):e1914180. doi:10.1001/jamanetworkopen.2019.14180
ORTHOPEDICS
Jasvinder A. Singh, MBBS, MPH; Michael J. Kallan, MS; Yong Chen, PhD; et al.
This cohort study examines the association of race/ethnicity with discharge disposition and 90-day hospital readmission overall and stratified by age among patients who have undergone total knee arthroplasty.
JAMA Netw Open. 2019;2(10):e1914259. doi:10.1001/jamanetworkopen.2019.14259
CARDIOLOGY
Rajesh Kabra, MD; Saket Girotra, MD, SM; Mary Vaughan Sarrazin, PhD
This cohort study of patients with atrial fibrillation who underwent left atrial appendage closure with an implanted device evaluates postprocedural mortality rates and rates of readmission and ischemic stroke.
JAMA Netw Open. 2019;2(10):e1914268. doi:10.1001/jamanetworkopen.2019.14268
NEUROLOGY
Dara McCreary, MSc; Ebun Omoyinmi, PhD; Ying Hong, PhD; et al.
This cohort study describes the development and validation of a targeted next-generation sequencing gene panel to identify monogenic disease-causing mutations in children with unclassified neuroinflammation.
JAMA Netw Open. 2019;2(10):e1914274. doi:10.1001/jamanetworkopen.2019.14274
HEALTH POLICY
Cesar Garriga, PhD; José Leal, DPhil; Maria T. Sánchez-Santos, MSc; et al.
This cohort study evaluates variation in patient outcomes and costs for primary hip and knee replacement across health areas in England and identifies whether patient, surgical, or hospital factors are associated with such variation.
JAMA Netw Open. 2019;2(10):e1914325. doi:10.1001/jamanetworkopen.2019.14325
PSYCHIATRY
Catharina Voss, MSc; Theresa M. Ollmann, MSc; Marcel Miché, PhD; et al.
This cross-sectional epidemiological study of a random community sample of adolescents and young adults in Dresden, Germany, examines the prevalence and timing of suicidal ideation, planning, and attempt.
JAMA Netw Open. 2019;2(10):e1914386. doi:10.1001/jamanetworkopen.2019.14386
ONCOLOGY
Ravi B. Parikh, MD, MPP; Christopher Manz, MD; Corey Chivers, PhD; et al.
This cohort study develops, validates, and compares machine learning algorithms that use structured electronic health record data before a clinic visit to predict mortality among patients with cancer.
JAMA Netw Open. 2019;2(10):e1915997. doi:10.1001/jamanetworkopen.2019.15997