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October 2024 - January 1908

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Issue

May 2022, Vol 182, No. 5, Pages 467-579

Original Investigation

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis

Paula Byrne, PhD; Maryanne Demasi, PhD; Mark Jones, PhD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):474-481. doi:10.1001/jamainternmed.2022.0134

This systematic review and meta-analysis examines the association between absolute reductions in low-density lipoprotein cholesterol levels with treatment with statin therapy and all-cause mortality, myocardial infarction, and stroke.

Less Is More

Outcomes and Safety of History-Based Screening for Medication Abortion: A Retrospective Multicenter Cohort Study

Ushma D. Upadhyay, PhD, MPH; Elizabeth G. Raymond, MD, MPH; Leah R. Koenig, MSPH; et al.
Abstract Full Text
open access
JAMA Intern Med. 2022;182(5):482-491. doi:10.1001/jamainternmed.2022.0217

This cohort study evaluates the outcomes and safety of a history-based screening, no-test approach to medication abortion care.

Accessible Hepatitis C Care for People Who Inject Drugs: A Randomized Clinical Trial

Benjamin Eckhardt, MD; Pedro Mateu-Gelabert, PhD; Yesenia Aponte-Melendez, PhD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):494-502. doi:10.1001/jamainternmed.2022.0170

This randomized clinical trial examines the efficacy of an accessible care model for treating hepatitis C virus in people who inject drugs.

Perinatal Complications in Individuals in California With or Without SARS-CoV-2 Infection During Pregnancy

Assiamira Ferrara, MD, PhD; Monique M. Hedderson, PhD; Yeyi Zhu, PhD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):503-512. doi:10.1001/jamainternmed.2022.0330

This cohort study examines the risk for perinatal complications in pregnant individuals with SARS-CoV-2 infection.

Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Risk of Gallbladder and Biliary Diseases: A Systematic Review and Meta-analysis of Randomized Clinical Trials

Liyun He, MM; Jialu Wang, MM; Fan Ping, MD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):513-519. doi:10.1001/jamainternmed.2022.0338

This systematic review and meta-analysis of 76 randomized clinical trials examines the effects of glucagon-like peptide-1 receptor agonist use on the risk of gallbladder and biliary diseases.

Association of Antipsychotic Drug Exposure in Pregnancy With Risk of Neurodevelopmental Disorders: A National Birth Cohort Study

Loreen Straub, MD, MS; Sonia Hernández-Díaz, MD, DrPH; Brian T. Bateman, MD, MS; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):522-533. doi:10.1001/jamainternmed.2022.0375

This nationwide birth cohort study of 3.4 million children nested in nationwide health care utilization data with up to 14 years of follow-up evaluates the risk of specific neurodevelopment disorders associated with in utero exposure to antipsychotic medications.

Deprescribing Education vs Usual Care for Patients With Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial

Elizabeth A. Bayliss, MD, MSPH; Susan M. Shetterly, MS; Melanie L. Drace, MPH; et al.
Abstract Full Text
open access
JAMA Intern Med. 2022;182(5):534-542. doi:10.1001/jamainternmed.2022.0502

This cluster randomized clinical trial examines the effectiveness of educating patients and clinicians about the potential to deprescribe unnecessary or risky medications among patients with dementia or mild cognitive impairment.

Editorial

JAMA Internal Medicine鈥擸ear in Review, 2021

Rita F. Redberg, MD, MSc
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):469-470. doi:10.1001/jamainternmed.2022.0464

New US Preventive Services Task Force Recommendations on Screening for Eating Disorders

Jason M. Nagata, MD, MSc; Neville H. Golden, MD
Abstract Full Text
free access has audio
JAMA Intern Med. 2022;182(5):471-473. doi:10.1001/jamainternmed.2022.0121
  • Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults
Invited Commentary

It Is Time to Change the Standard of Medication Abortion

Jennifer Karlin, MD, PhD; Jamila Perritt, MD, MPH
Abstract Full Text
JAMA Intern Med. 2022;182(5):491-493. doi:10.1001/jamainternmed.2022.0216

Glucagon-Like Peptide-1 Receptor Agonists鈥擧ow Safe Are They?

Shanzay Haider, MD; Kasia J. Lipska, MD, MHS
Abstract Full Text
JAMA Intern Med. 2022;182(5):520-521. doi:10.1001/jamainternmed.2022.0335
Editor's Note

Curing Hepatitis C鈥擱equires More Than a Prescription

Asha Choudhury, MD, MPH, MS; Mitchell H. Katz, MD
Abstract Full Text
JAMA Intern Med. 2022;182(5):502. doi:10.1001/jamainternmed.2022.0181
Teachable Moment

Less Is More

Inpatient Management of Type 2 Diabetes

Shane Warnock, MD; Niloofar Latifi, MD
Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(5):543-544. doi:10.1001/jamainternmed.2022.0410

This Teachable Moment describes treatment plans that reduce the frequency of finger stick blood glucose checks for patients with type 2 diabetes.

Less Is More

The Harms of Postoperative Antibiotic Prophylaxis: A Teachable Moment

Sheliza Halani, MD; Mark McIntyre, PharmD, RPh; Alon Vaisman, MD, MAS
Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(5):545-546. doi:10.1001/jamainternmed.2022.0413

This Teachable Moment describes a man in his 70s with coronary artery disease who presented to the emergency department with fever and chills and was diagnosed with Clostridium difficile infection.

Research Letter

Comparison of US Cancer Center Recommendations for Prostate Cancer Screening With Evidence-Based Guidelines

Elizabeth S. Koh, BA; Andrew Y. J. Lee, BS; Behfar Ehdaie, MD, MPH; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):555-556. doi:10.1001/jamainternmed.2022.0091

This cross-sectional study examines prostate cancer recommendations among US cancer centers to identify differences from clinical practice guidelines.

US Food and Drug Administration鈥揗andated Postmarketing Studies for High-risk Cardiovascular Devices Approved 2015-2019

Danelle Hidano, MD; Sanket S. Dhruva, MD, MHS; Rita F. Redberg, MD, MSc
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):556-558. doi:10.1001/jamainternmed.2022.0184

This qualitative study assesses the availability and strength of evidence of postapproval studies for high-risk cardiovascular devices subsequent to the 21st Century Cures Act.

Workforce Providing Abortion Care and Management of Pregnancy Loss in the US

Julia Strasser, DrPH, MPH; Ellen Schenk, MPP; Kirsten Das, MD; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):558-559. doi:10.1001/jamainternmed.2022.0223

This cross-sectional study uses national medical claims data set to examine the workforce providing abortion care and management of pregnancy loss.

Evaluation of Evidence-Based Dual Antiplatelet Therapy for Secondary Prevention in US Patients With Acute Ischemic Stroke

Ying Xian, MD, PhD; Haolin Xu, MS; Eric E. Smith, MD, MPH; et al.
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):559-564. doi:10.1001/jamainternmed.2022.0323

This cohort study examines patterns in prescriptions of dual antiplatelet therapy after publication of important trials and release of updated guidelines.

Medical Documentation Burden Among US Office-Based Physicians in 2019: A National Study

Adam Gaffney, MD, MPH; Stephanie Woolhandler, MD, MPH; Christopher Cai, MD; et al.
Abstract Full Text
free access has audio
JAMA Intern Med. 2022;182(5):564-566. doi:10.1001/jamainternmed.2022.0372

This cross-sectional study uses data from the 2019 National Electronic Health Records Survey to assess the burden and time spent on medical documentation outside office hours among US physicians.

  • Podcast: Medical Documentation Burden Among US Office-Based Physicians
Challenges in Clinical Electrocardiography

Where Is the Culprit Lesion in the New Electrocardiogram Pattern?

Chuan-Hai Zhang, MD; Zhaolong Xu, MD
Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(5):547-548. doi:10.1001/jamainternmed.2022.0011

This case report presents the electrocardiogram findings of a patient in their 60s with paroxysmal chest pain.

Acute Myocardial Infarction With Wide Complex Rhythm: What Is the Culprit Artery?

Qinghua Chang, MD; Yuanzhe Jin, MD
Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(5):549-550. doi:10.1001/jamainternmed.2022.0122

This case report presents the electrocardiographic findings of a man in his 70s who presented to the emergency department with sudden-onset chest pain and profuse sweating.

Diagnostic Dilemma of Pericarditis Concurrent With ST Elevation Myocardial Infarction

Mochammad Yusuf Alsagaff, MD, PhD; Yudi Her Oktaviono, MD, PhD; Terrence Timothy Evan Lusida, MD
Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(5):551-552. doi:10.1001/jamainternmed.2022.0318

This case report presents the electrocardiogram findings of a 57-year-old man with persistent diffuse ST elevation after failed treatment with streptokinase therapy.

Tachycardiomyopathy鈥擳he Eye Cannot See What the Mind Does Not Know

Gauravkumar Divani, MD, DM; Anunay Gupta, MD, DM; Ankit Jain, MD, DM
Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(5):553-554. doi:10.1001/jamainternmed.2022.0515

This case report describes a patient in his 20s with no comordities who presented with recurrent heart palpitations and progressive heart failure for 6 months.

Comment & Response

Follow-up Duration and Gender Differences in Study of Older Adults Living Alone

Mengyang He, MD; Minjing Luo, MD; Jinchang Huang, PhD
Abstract Full Text
JAMA Intern Med. 2022;182(5):566. doi:10.1001/jamainternmed.2022.0058

Follow-up Duration and Gender Differences in a Study of Older Adults Living Alone鈥擱eply

Sachin J. Shah, MD, MPH; Kenneth E. Covinsky, MD, MPH
Abstract Full Text
JAMA Intern Med. 2022;182(5):566-567. doi:10.1001/jamainternmed.2022.0061

Point-of-Care Ultrasonography: Clearly More Than a Pretty Picture

Hamid Shokoohi, MD, MPH; Andrew S. Liteplo, MD; Irene W. Y. Ma, MD, PhD, RDMS, RDCS
Abstract Full Text
JAMA Intern Med. 2022;182(5):567. doi:10.1001/jamainternmed.2022.0067

Point-of-Care Ultrasonography: Clearly More Than a Pretty Picture

Timothy J. Wilt, MD, MPH; Carolyn J. Crandall, MD, MS; Amir Qaseem, MD, PhD, MHA
Abstract Full Text
JAMA Intern Med. 2022;182(5):567-568. doi:10.1001/jamainternmed.2022.0070

Point-of-Care Ultrasonography: Clearly More Than a Pretty Picture鈥擱eply

Eden Bernstein, MD; Tracy Y. Wang, MD, MHS, MSc
Abstract Full Text
JAMA Intern Med. 2022;182(5):568. doi:10.1001/jamainternmed.2022.0073

Maybe Not an Acute Inferior Myocardial Infarction

Yi-Wei Cao, MD; Hao-Yu Wu, MD, PhD
Abstract Full Text
JAMA Intern Med. 2022;182(5):569. doi:10.1001/jamainternmed.2022.0096

Maybe Not an Acute Inferior Myocardial Infarction鈥擱eply

Desmond B. Jay, MD; Timothy D. Henry, MD; Scott W. Sharkey, MD
Abstract Full Text
JAMA Intern Med. 2022;182(5):569. doi:10.1001/jamainternmed.2022.0099

A Different Case of Penumbra: A Japanese Framework for Safe and Expedited Access to High-risk Medical Devices

Haruko Yamamoto, MD, PhD; Tetsuya Kusakabe, PhD; Mimei Takahashi, RPh
Abstract Full Text
JAMA Intern Med. 2022;182(5):569-570. doi:10.1001/jamainternmed.2022.0102

A Different Case of Penumbra鈥擱eply: A Japanese Framework for Safe and Expedited Access to High-Risk Medical Devices

Kushal T. Kadakia, MSc; Joseph S. Ross, MD, MHS; Harlan M. Krumholz, MD, SM
Abstract Full Text
JAMA Intern Med. 2022;182(5):570-571. doi:10.1001/jamainternmed.2022.0105

Inhaled Ciclesonide for Patients With Asthma or Chronic Obstructive Pulmonary Disease and COVID-19

Chao-Hsien Chen, MD; Cheng-Yi Wang, MD; Chih-Cheng Lai, MD
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):571-572. doi:10.1001/jamainternmed.2022.0207

Inhaled Ciclesonide for Patients With Asthma or Chronic Obstructive Pulmonary Disease and COVID-19鈥擱eply

Brian M. Clemency, DO; David J. Koster, MS; Michael S. Blaiss, MD
Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):572. doi:10.1001/jamainternmed.2022.0210

Missed Signs of Acute Pulmonary Embolism in Electrocardiogram Findings

Yun-Tao Zhao, MD, PhD; Lei Wang, MD
Abstract Full Text
JAMA Intern Med. 2022;182(5):572-573. doi:10.1001/jamainternmed.2022.0384

Missed Signs of Acute Pulmonary Embolism in Electrocardiogram Findings

Ting-Ting Li, MD; Xiaohong Chen, MD
Abstract Full Text
JAMA Intern Med. 2022;182(5):573. doi:10.1001/jamainternmed.2022.0387

Missed Signs of Acute Pulmonary Embolism in Electrocardiogram Findings鈭扲eply

Ian S. deSouza, MD; Jane Belyavskaya, MD
Abstract Full Text
JAMA Intern Med. 2022;182(5):573-574. doi:10.1001/jamainternmed.2022.0390

Physical Maneuvers and Recent Tools to Break the Silence of Clinically Undetectable Heart Sounds

John Maidens, PhD; John S. Chorba, MD; James D. Thomas, MD
Abstract Full Text
JAMA Intern Med. 2022;182(5):574-575. doi:10.1001/jamainternmed.2022.0399

Physical Maneuvers and Recent Tools to Break the Silence of Clinically Undetectable Heart Sounds

Oscar M. P. Jolobe, DPhil, MRCP(UK)
Abstract Full Text
JAMA Intern Med. 2022;182(5):575. doi:10.1001/jamainternmed.2022.0402

Physical Maneuvers and Recent Tools to Break the Silence of Clinically Undetectable Heart Sounds鈥擱eply

Nancy Jariwala; Seth Klapman, MBA, MD; Jonathon McBride, MS
Abstract Full Text
JAMA Intern Med. 2022;182(5):575-576. doi:10.1001/jamainternmed.2022.0405

Serology Test Results and Other Important Characteristics of Patients With Persistent COVID-19 Symptoms

Yochai Re鈥檈m, MD; Menelaos Symeonides, PhD; Lisa McCorkell, MPP
Abstract Full Text
JAMA Intern Med. 2022;182(5):576-577. doi:10.1001/jamainternmed.2022.0418

Serology Test Results and Other Important Characteristics of Patients With Persistent COVID-19 Symptoms

Michiel Tack
Abstract Full Text
JAMA Intern Med. 2022;182(5):577. doi:10.1001/jamainternmed.2022.0421

Serology Test Results and Other Important Characteristics of Patients With Persistent COVID-19 Symptoms鈥擱eply

Cédric Lemogne, MD, PhD; Joane Matta, PhD; Olivier Robineau, MD, PhD
Abstract Full Text
JAMA Intern Med. 2022;182(5):577-578. doi:10.1001/jamainternmed.2022.0424
Correction

Numerical Errors and Clarification of Study Participants With Undefined Responses, Missing Data, and Complete Data

Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):579. doi:10.1001/jamainternmed.2022.0450

Error in Quiz Answer Choice Caused by Error in Related Article

Abstract Full Text
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JAMA Intern Med. 2022;182(5):579. doi:10.1001/jamainternmed.2022.0451

Error in Abstract and Results

Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):579. doi:10.1001/jamainternmed.2022.0668

Error in Figure 3

Abstract Full Text
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JAMA Intern Med. 2022;182(5):579. doi:10.1001/jamainternmed.2022.1671
Peer Reviewers List

JAMA Internal Medicine Peer Reviewers in 2021

Abstract Full Text
free access online only
JAMA Intern Med. 2022;182(5):e220153. doi:10.1001/jamainternmed.2022.0153
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2022;182(5):467. doi:10.1001/jamainternmed.2021.6077
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