ÌÇÐÄvlog

This cohort study assesses which patients with advanced solid tumors derive the greatest clinical benefit from next-generation sequencing.

This randomized clinical trial compares magnetic resonance imaging with targeted biopsy with systematic biopsy for the diagnosis of clinically significant prostate cancer.

This ancillary study of the NRG/RTOG 9601 randomized clinical trial assesses the validity of a genomic classifier to estimate the risk of distant metastasis after radical prostatectomy in patients with prostate cancer.

This exploratory analysis of a randomized clinical trial evaluates the association of bone metastasis count and location with survival benefit from prostate radiotherapy in patients with newly diagnosed metastatic prostate cancer.

This randomized, multicenter clinical trial assesses changes in estradiol levels in male patients with hormone receptor–positive breast cancer after treatment with aromatase inhibitor plus gonadotropin-releasing hormone analogue, with gonadotropin-releasing hormone analogue plus tamoxifen, or with tamoxifen alone.

This phase 3 randomized clinical trial compares the clinical efficacy of margetuximab vs trastuzumab, each with chemotherapy, in patients with pretreated ERBB2-positive advanced breast cancer.

This case series uses data from 876 families with BRCA1 and BRCA2 variants from the Breast Cancer Family Registry to assess whether risk-reducing salpingo-oophorectomy is associated with a reduction in breast cancer risk for women carrying these pathogenic variants.