Louise Ninett Carlsen, MD; Signe Bruun Munksgaard, MD, PhD; Mia Nielsen, MD; et al.
free access
JAMA Neurol. 2020;77(9):1069-1078. doi:10.1001/jamaneurol.2020.1179
This randomized clinical trial compares 3 treatment strategies among patients with medication overuse headache in Denmark.
Céline Louapre, MD; Nicolas Collongues, MD; Bruno Stankoff, MD; et al.
free access
JAMA Neurol. 2020;77(9):1079-1088. doi:10.1001/jamaneurol.2020.2581
This cohort study describes the clinical characteristics and outcomes in patients with multiple sclerosis who contract COVID-19 and identifies factors associated with COVID-19 severity.
Radu Tanasescu, MD, PhD; Christopher R. Tench, PhD; Cris S. Constantinescu, MD, PhD; et al.
free access
JAMA Neurol. 2020;77(9):1089-1098. doi:10.1001/jamaneurol.2020.1118
This randomized clinical trial assesses the effect of hookworm treatment on magnetic resonance imaging activity and T regulatory cells in British patients with relapsing multiple sclerosis.
Suzanne Craft, PhD; Rema Raman, PhD; Tiffany W. Chow, MD; et al.
free access
has audio
JAMA Neurol. 2020;77(9):1099-1109. doi:10.1001/jamaneurol.2020.1840
This randomized clinical trial examines the safety, efficacy, and feasibility of intranasal insulin for the treatment of persons with mild cognitive impairment and Alzheimer disease dementia.
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Podcast:
Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia
Salomeh Keyhani, MD, MPH; Eric M. Cheng, MD; Katherine J. Hoggatt, PhD; et al.
open access
JAMA Neurol. 2020;77(9):1110-1121. doi:10.1001/jamaneurol.2020.1427
This comparative effectiveness study describes the analytical strategy, methods, and results of a target trial emulation examining cohorts of US veterans with carotid stenosis.
Jerry R. Mendell, MD; Zarife Sahenk, MD, PhD; Kelly Lehman, MSN; et al.
open access
JAMA Neurol. 2020;77(9):1122-1131. doi:10.1001/jamaneurol.2020.1484
This nonrandomized controlled trial analyzes safety, biological, and functional outcomes associated with the infusion of rAAVrh74.MHCK7.micro-dystrophin gene transfer in a small group of patients with Duchenne muscular dystrophy.
Ludwig Kappos, MD; Jerry S. Wolinsky, MD; Gavin Giovannoni, PhD; et al.
open access
JAMA Neurol. 2020;77(9):1132-1140. doi:10.1001/jamaneurol.2020.1568
This secondary analysis of data from 2 randomized clinical trials examines the relative contribution of relapse-associated vs relapse-independent progression to overall confirmed disability accumulation in patients with multiple sclerosis and assesses respective baseline prognostic factors and outcomes of the 2 treatments.
Alberto Bizzi, MD; Riccardo Pascuzzo, PhD; Janis Blevins, BSc; et al.
free access
JAMA Neurol. 2020;77(9):1141-1149. doi:10.1001/jamaneurol.2020.1319
This diagnostic study assesses the sensitivity and specificity of diffusion magnetic resonance imaging with a new criterion of at least 1 positive brain region for the diagnosis of sporadic Creutzfeldt-Jakob disease.
Gregory W. J. Hawryluk, MD, PhD; Jessica L. Nielson, PhD; J. Russell Huie, PhD; et al.
free access
JAMA Neurol. 2020;77(9):1150-1158. doi:10.1001/jamaneurol.2020.1310
This study investigates associations between intracranial pressure values and outcomes in neurocritical care patients.