Liane E. Hunter, PhD; Yun Freudenberg-Hua, MD; Peter Davies, PhD; et al.
free access
has audio
JAMA Neurol. 2020;77(4):419-426. doi:10.1001/jamaneurol.2019.4828
This cross-sectional study examines whether the apolipoprotein E ε4 allele and 12-month ball heading exposure are associated with verbal memory in a cohort of adult amateur soccer players.
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Podcast:
Associations of APOE ε4 Genotype and Ball Heading With Verbal Memory in Amateur Soccer Players
Stephen Mullin, PhD, MRCP; Laura Smith, MSc; Katherine Lee, MRes; et al.
open access
JAMA Neurol. 2020;77(4):427-434. doi:10.1001/jamaneurol.2019.4611
This single-center open-label nonrandomized, noncontrolled trial assesses the safety, tolerability, cerebrospinal fluid penetration, and biochemical changes associated with ambroxol therapy for the treatment of patients with Parkinson disease with and without mutations in the glucocerebrosidase gene.
Anthony P. Kontos, PhD; Kendra Jorgensen-Wagers, PhD; Alicia M. Trbovich, PhD; et al.
free access
JAMA Neurol. 2020;77(4):435-440. doi:10.1001/jamaneurol.2019.4552
This cross-sectional study investigates the association of the time from a sports injury to the initiation of clinical care with recovery time after concussion in adolescents and young adults.
Angela K. Birnbaum, PhD; Kimford J. Meador, MD; Ashwin Karanam, PharmD; et al.
free access
JAMA Neurol. 2020;77(4):441-450. doi:10.1001/jamaneurol.2019.4443
This cohort study aims to provide direct, objective information on infants’ antiepileptic drug exposure through breast milk.
Jack F. V. Hunt, BA; William Buckingham, PhD; Alice J. Kim, BA; et al.
free access
JAMA Neurol. 2020;77(4):451-460. doi:10.1001/jamaneurol.2019.4501
This cross-sectional study examines whether neighborhood-level socioeconomic disadvantage is associated with decreased brain volume in a cognitively unimpaired population enriched for Alzheimer disease risk.
Stuart H. Isaacson, MD; William Ondo, MD; Carlayne E. Jackson, MD; et al.
open access
JAMA Neurol. 2020;77(4):461-469. doi:10.1001/jamaneurol.2019.4565
This randomized clinical trial evaluates the safety and efficacy of rimabotulinumtoxinB injections in the management of sialorrhea in adults.
Joseph Therriault, BSc; Andrea L. Benedet, MSc; Tharick A. Pascoal, MD, PhD; et al.
open access
JAMA Neurol. 2020;77(4):470-479. doi:10.1001/jamaneurol.2019.4421
This study investigates whether apolipoprotein E ε4 is associated with medial temporal tau pathology independently of amyloid-β, sex, clinical status, and age.
Christina N. Fournier, MD, MSc; Richard Bedlack, MD, PhD, MS; Colin Quinn, MD; et al.
free access
JAMA Neurol. 2020;77(4):480-488. doi:10.1001/jamaneurol.2019.4490
This study describes the development and validation of a new self-reported amyotrophic lateral sclerosis disability scale.
Jed A. Hartings, PhD; Norberto Andaluz, MD; M. Ross Bullock, MD; et al.
free access
JAMA Neurol. 2020;77(4):489-499. doi:10.1001/jamaneurol.2019.4476
This multicenter cohort study assesses the association between spreading depolarizations in the brains of individuals who have undergone surgery for traumatic brain injury and neurologic outcomes.
Aaron F. Struck, MD; Mohammad Tabaeizadeh, MD; Sarah E. Schmitt, MD; et al.
free access
JAMA Neurol. 2020;77(4):500-507. doi:10.1001/jamaneurol.2019.4656
This study assesses the validity of the 2HELPS2B score in predicting risk for electrographic seizures among patients undergoing electroencephalogram.
Pierre-François Meyer, PhD; Alexa Pichet Binette, MSc; Julie Gonneaud, PhD; et al.
free access
JAMA Neurol. 2020;77(4):508-516. doi:10.1001/jamaneurol.2019.4749
This study characterizes individuals in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) data set with tau abnormality indicated by cerebrospinal fluid assay or positron emission tomography.