Clinical Trial
Tobias Cronberg, MD, PhD; Gisela Lilja, OT; Janneke Horn, MD, PhD; et al.
free access
JAMA Neurol. 2015;72(6):634-641. doi:10.1001/jamaneurol.2015.0169
This multicenter randomized clinical trial found good quality of life in patients with cardiac arrest receiving targeted temperature management.
Pedro M. Rodríguez Cruz, MD, MSc; Michal Al-Hajjar, MD; Saif Huda, MB, ChB; et al.
free access
JAMA Neurol. 2015;72(6):642-649. doi:10.1001/jamaneurol.2015.0203
This cohort study determines the diagnostic usefulness of cell-based assays in the diagnosis of myasthenia gravis and compares the clinical features of patients with antibodies only to clustered acetylcholine receptors with those of patients with seronegative myasthenia gravis. See the Editorial by Vernino.
John P. Betjemann, MD; S. Andrew Josephson, MD; Daniel H. Lowenstein, MD; et al.
free access
JAMA Neurol. 2015;72(6):650-655. doi:10.1001/jamaneurol.2015.0188
This retrospective study of patients with status epilepticus demonstrated that status epilepticus鈥搑elated mortality remained relatively steady from 1999 to 2010, but the rate of hospitalizations for status epilepticus increased significantly in the same period.
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Editorial
Status Epilepticus: Redefined or Increasingly Detected?
Amy C. Jongeling, MD, PhD; Carl W. Bazil, MD, PhD; Jan Claassen, MD
JAMA Neurol
Rawan Tarawneh, MD; Denise Head, PhD; Samantha Allison, MA; et al.
free access
JAMA Neurol. 2015;72(6):656-665. doi:10.1001/jamaneurol.2015.0202
This longitudinal observational study investigates the usefulness of CSF VILIP-1, tau, p-tau181, and A尾42 levels in predicting rates of whole-brain and regional atrophy in early AD and cognitively normal control subjects over time.
Michela Ripolone, PhD; Dario Ronchi, PhD; Raffaella Violano, BS; et al.
free access
JAMA Neurol. 2015;72(6):666-675. doi:10.1001/jamaneurol.2015.0178
This review of oxidative metabolism in biopsy samples finds that an altered regulation of myogenesis and a downregulated mitochondrial biogenesis contribute to pathologic change in the muscle of patients with spinal muscular atrophy.
Avi Gadoth, MD; Beatrice Nefussy, PhD; Margalit Bleiberg, PhD; et al.
free access
JAMA Neurol. 2015;72(6):676-681. doi:10.1001/jamaneurol.2015.48
This case-control study suggests that an amyotrophic lateral sclerosis syndrome might be associated with autoimmunity and gluten sensitivity.
Jie Ding, PhD; Sigurdur Sigurdsson, MSc; Melissa Garcia, MPH; et al.
free access
JAMA Neurol. 2015;72(6):682-688. doi:10.1001/jamaneurol.2015.0174
This population-based brain imaging study finds similar risk factors for intracerebral hemorrhage and cerebral microbleeds (CMBs), with a distinction between lobar and deep CMBs, in a sample of people older than 65 years.
Kristen Zukosky, PhD; Katherine Meilleur, PhD; Bryan J. Traynor, MD, PhD; et al.
free access
has multimedia
JAMA Neurol. 2015;72(6):689-698. doi:10.1001/jamaneurol.2015.37
This observational genetics study identifies a new scapuloperoneal phenotype associated with an ACTA1 mutation.
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Video:
Patient VI-2, Gower sign 1
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Video:
Patient VI-2, Gower sign 2
Rodrigo P. Almeida, BS; Stephanie A. Schultz, BS; Benjamin P. Austin, PhD; et al.
free access
JAMA Neurol. 2015;72(6):699-706. doi:10.1001/jamaneurol.2015.0098
This cross-sectional cohort study investigates whether cognitive reserve modifies the adverse influence of age on key cerebrospinal fluid biomarkers of Alzheimer disease in a cognitively normal group and a cognitively impaired group.