Michael Cecchini, MD; Ronald R. Salem, MD; Marie Robert, MD; et al.
open access
JAMA Oncol. 2024;10(8):1027-1035. doi:10.1001/jamaoncol.2024.1575
This nonrandomized clinical trial assesses whether neoadjuvant modified 5-fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFIRINOX) leads to early control of micrometastasis and improves survival.
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Invited Commentary
The Sequencing Conundrum in Localized Pancreatic Adenocarcinoma—Progress or Passive Acceptance?
Priyadarshini Pathak, MBBS; Colin D. Weekes, MD, PhD; Rachna T. Shroff, MD, MS
JAMA Oncol
Daniel R. Richardson, MD, MA, MSc; Xi Zhou, PhD; Katherine Reeder-Hayes, MBA, MD; et al.
JAMA Oncol. 2024;10(8):1038-1046. doi:10.1001/jamaoncol.2024.1823
This retrospective cohort study quantifies and compares home time for older patients with newly diagnosed acute myeloid leukemia receiving either hypomethylating agents or anthracycline-based chemotherapy.
Wenzhe Fan, MD; Bowen Zhu, MSc; Shuling Chen, MD; et al.
JAMA Oncol. 2024;10(8):1047-1054. doi:10.1001/jamaoncol.2024.1831
This randomized clinical trial evaluates the efficacy and safety of transarterial chemoembolization (TACE) plus sorafenib vs TACE alone for patients with recurrent intermediate-stage hepatocellular carcinoma.
Timothée Olivier, MD; Alyson Haslam, PhD; Vinay Prasad, MD, MPH
open access
JAMA Oncol. 2024;10(8):1055-1059. doi:10.1001/jamaoncol.2024.1569
This systematic review examines the proportion and quality of postrecurrence treatment among patients in US Food and Drug Administration (FDA) registration trials of anticancer therapy in the neoadjuvant or adjuvant setting.
Alise Blake, MS, CGC; Melissa R. Perrino, MD; Cara E. Morin, MD, PhD; et al.
JAMA Oncol. 2024;10(8):1060-1067. doi:10.1001/jamaoncol.2024.1878
This cohort study evaluates surveillance outcomes across a wide spectrum of cancer predisposition syndromes in children and young adults.
Kemi M. Doll, MD, MSCR; Mindy Pike, PhD; Julianna Alson, MPH; et al.
has audio
JAMA Oncol. 2024;10(8):1068-1076. doi:10.1001/jamaoncol.2024.1891
This diagnostic study of Black patients assesses the false-negative probability and accuracy of ultrasonography-measured endometrial thickness thresholds as triage for endometrial cancer diagnosis.
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Podcast:
Endometrial Thickness as Diagnostic Triage for Endometrial Cancer in Black Individuals
Veerle C. M. Geurts, MD; Sara Balduzzi, PhD; Tessa G. Steenbruggen, MD, PhD; et al.
JAMA Oncol. 2024;10(8):1077-1086. doi:10.1001/jamaoncol.2024.1917
This cohort study examines the association between the presence of stromal tumor-infiltrating lymphocytes and survival among patients with stage I triple-negative breast cancer (TNBC) for whom chemotherapy may not be beneficial.
Amanda L. Blackford, ScM; Marcia Irene Canto, MD, MHS; Mohamad Dbouk, MD; et al.
open access
JAMA Oncol. 2024;10(8):1087-1096. doi:10.1001/jamaoncol.2024.1930
This cohort study compares survival of high-risk patients with screen-detected pancreatic cancer with a matched cohort from the Surveillance, Epidemiology, and End Results program.
Nikhile Mookerji, MD; Tyler Pfanner, MD; Amaris Hui, MD; et al.
open access
JAMA Oncol. 2024;10(8):1097-1103. doi:10.1001/jamaoncol.2024.3196
This study assesses the accuracy of fluorine-18 prostate-specific membrane antigen–1007 positron emission tomography (PET)/computed tomography (CT) compared to multiparametric magnetic resonance imaging (MRI) in locoregional staging of prostate cancer.