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October 2024 - April 2015

Decade

Year

Issue

July 2024, Vol 10, No. 7, Pages 856-992

Original Investigation

Longer Interval Between First Colonoscopy With Negative Findings for Colorectal Cancer and Repeat Colonoscopy

Abstract Full Text
JAMA Oncol. 2024;10(7):866-873. doi:10.1001/jamaoncol.2024.0827

This cohort study uses registry data to examine the risk of colorectal cancer (CRC) and CRC-specific death for up to 20 years after having a first colonoscopy with findings negative for CRC.

Cardiovascular Events and Androgen Receptor Signaling Inhibitors in Advanced Prostate Cancer: A Systematic Review and Meta-Analysis

Abstract Full Text
JAMA Oncol. 2024;10(7):874-884. doi:10.1001/jamaoncol.2024.1549

This systematic review and meta-analysis investigates the incidence of cardiovascular events with addition of novel androgen receptor signaling inhibitors (ARSI) to standard of care in locally advanced and metastatic prostate cancer.

Systemic Anticancer Therapy and Overall Survival in Patients With Very Advanced Solid Tumors

Abstract Full Text
open access
JAMA Oncol. 2024;10(7):887-895. doi:10.1001/jamaoncol.2024.1129

This cohort study evaluates whether the overall population of patients with metastatic cancer receiving care at practices with higher rates of oncologic therapy for very advanced disease experienced longer survival.

Intensity-Modulated Reirradiation Therapy With Nivolumab in Recurrent or Second Primary Head and Neck Squamous Cell Carcinoma: A Nonrandomized Controlled Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):896-904. doi:10.1001/jamaoncol.2024.1143

This nonrandomized controlled trial assessed the benefits and toxic effects of intensity-modulated reirradiation therapy with nivolumab in the treatment of patients with recurrent or second primary head and neck squamous cell carcinoma.

Long-Term Engagement of Patients With Advanced Cancer: Results From the EPAC Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):905-911. doi:10.1001/jamaoncol.2024.1221

This secondary analysis of data from the EPAC randomized clinical trial examines the association of a lay health worker鈥搇ed advance care planning intervention among patients with advanced stages of cancer with overall survival and end-of-life health care use and costs.

Comprehensive Audiologic Analyses After Cisplatin-Based Chemotherapy

Abstract Full Text
JAMA Oncol. 2024;10(7):912-922. doi:10.1001/jamaoncol.2024.1233

This cohort study evaluates cisplatin-related hearing loss with comprehensive audiologic assessments, assesses the longitudinal progression of cisplatin-related hearing loss, and identifies factors associated with risk.

Neoadjuvant Nivolumab Plus Chemotherapy Followed By Response-Adaptive Therapy for HPV+ Oropharyngeal Cancer: OPTIMA II Phase 2 Open-Label Nonrandomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):923-931. doi:10.1001/jamaoncol.2024.1530

This phase 2 nonrandomized clinical trial evaluates effectiveness and tolerance of neoadjuvant nivolumab, nab-paclitaxel, and carboplatin followed by response-adaptive therapy in patients with human papillomavirus鈭抪ositive oropharyngeal cancer.

Circulating Tumor DNA-Guided De-Escalation Targeted Therapy for Advanced Non鈭扴mall Cell Lung Cancer: A Nonrandomized Controlled Trial

Abstract Full Text
open access
JAMA Oncol. 2024;10(7):932-940. doi:10.1001/jamaoncol.2024.1779

This nonrandomized controlled trial assesses the feasibility of using a circulating tumor DNA鈭抔uided adaptive de-escalation tyrosine kinase inhibitor strategy in patients with advanced non鈭抯mall cell lung cancer to achieve complete remission after local consolidative therapy.

Stereotactic Ablative Radiotherapy for Gynecological Oligometastatic and Oligoprogessive Tumors

Abstract Full Text
JAMA Oncol. 2024;10(7):941-948. doi:10.1001/jamaoncol.2024.1796

This cohort study evaluates the outcomes of stereotactic ablative radiotherapy in patients with oligometastatic and oligoprogressive gynecologic cancers.

Brief Report

Coaches Activating, Reaching, and Engaging Patients to Engage in Advance Care Planning: A Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):949-953. doi:10.1001/jamaoncol.2024.1242

This randomized clinical trial evaluates whether a multilevel advance care planning (ACP) intervention improves clinician ACP documentation for patients with advanced genitourinary cancers compared with a clinician-level intervention only.

Physician and Artificial Intelligence Chatbot Responses to Cancer Questions From Social Media

Abstract Full Text
JAMA Oncol. 2024;10(7):956-960. doi:10.1001/jamaoncol.2024.0836

This equivalence study compared the use of oncologist vs chatbot responses to patient questions regarding cancer in an online forum.

Dose-Adjusted EPOCH Plus Inotuzumab Ozogamicin in Adults With Relapsed or Refractory B-Cell ALL: A Phase 1 Dose-Escalation Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):961-965. doi:10.1001/jamaoncol.2024.0967

This phase 1 dose-escalation trial examines whether inotuzumab ozogamicin plus dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (EPOCH) is safe and effective for adults with relapsed or refractory B-cell acute lymphoblastic leukemia or lymphoma (ALL).

Research Letter

Genetic Testing in Men With Metastatic Castration-Resistant Prostate Cancer

Abstract Full Text
open access
JAMA Oncol. 2024;10(7):975-977. doi:10.1001/jamaoncol.2024.0851

This cross-sectional study assesses homologous recombination repair mutation genetic testing and associated characteristics among men with metastatic castration-resistant prostate cancer (mCRPC).

Climate Change in Comprehensive Cancer Control Plans in the US

Abstract Full Text
JAMA Oncol. 2024;10(7):977-979. doi:10.1001/jamaoncol.2024.1294

This cross-sectional study examines the inclusion of climate- and climate change鈥搑elated mitigation efforts in cancer prevention plans in US states, tribes, and territories.

Comprehensive Bridging Radiotherapy for Limited Pre-CART Non-Hodgkin Lymphoma

Abstract Full Text
JAMA Oncol. 2024;10(7):979-981. doi:10.1001/jamaoncol.2024.1113

This cohort study examines the role of comprehensive bridging radiotherapy in the setting of chimeric antigen receptor T-cell therapy for non-Hodgkin lymphoma.

Axillary Surgery for Chemoresidual (ypN-Positive) Nodal Disease

Abstract Full Text
JAMA Oncol. 2024;10(7):981-984. doi:10.1001/jamaoncol.2024.1136

This cohort study using pooled data from 2 randomized clinical trials examines whether removing more lymph nodes with axillary lymph node dissection improved outcomes over sentinel lymph node biopsy when most patients received adjuvant radiation therapy or regional nodal irradiation.

Radiation Therapy Followed by Intrathecal Trastuzumab-Pertuzumab for ERBB2-Positive Breast Leptomeningeal Disease: A Phase 1 Nonrandomized Controlled Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):984-986. doi:10.1001/jamaoncol.2024.1299

This nonrandomized controlled trial examines the safety of radiation therapy (RT) followed by intrathecal trastuzumab and pertuzumab for patients with ERBB2-positive breast leptomeningeal disease (LMD).

Review

Obstacles to Biosimilar Acceptance and Uptake in Oncology: A Review

Abstract Full Text
has active quiz
JAMA Oncol. 2024;10(7):966-972. doi:10.1001/jamaoncol.2024.1447

This narrative review discusses psychological, attitudinal, and educational factors among both health care professionals and payers that may play a role in slowing biosimilar uptake.

JAMA Oncology Clinical Challenge

A Patient With Slow Communication and Difficulty Walking

Abstract Full Text
JAMA Oncol. 2024;10(7):973-974. doi:10.1001/jamaoncol.2024.0978

A 70-year-old woman with hypertension and dyslipidemia presented with slow communication and difficulty walking 90 days after 6 courses of postoperative chemotherapy following right breast cancer surgery. What is your diagnosis?

Viewpoint

Compassionate Machines: The Ethics of 鈥淎rtificial Empathy鈥 in Cancer Care

Abstract Full Text
JAMA Oncol. 2024;10(7):857-858. doi:10.1001/jamaoncol.2024.0824

This Viewpoint discusses the ethics of artificial intelligence鈥揼enerated compassion in cancer care and outlines 4 main points of concern.

Watch and Wait for Near-Complete Responders鈥擜 Word of Caution

Abstract Full Text
JAMA Oncol. 2024;10(7):858-860. doi:10.1001/jamaoncol.2024.0856

This Viewpoint discusses the establishment of a cutoff point as the watch and wait approach is increasingly used in patients with locally advanced rectal cancer.

Dual Checkpoint Inhibition in Melanoma With 鈮1% PD-L1鈥擳ime to Reassess the Evidence

Abstract Full Text
JAMA Oncol. 2024;10(7):860-862. doi:10.1001/jamaoncol.2024.1117

This Viewpoint discusses use of anti鈥揚D-1 monotherapy as the primary treatment option for patients with treatment-naive metastatic melanoma staining positive for PD-L1 over dual checkpoint inhibition therapy.

Editorial

The Interval for Screening Colonoscopy鈥擨s 15 the New 10?

Abstract Full Text
JAMA Oncol. 2024;10(7):864-865. doi:10.1001/jamaoncol.2024.0249
Invited Commentary

Cardiovascular Risk in Prostate Cancer鈥擜 Call to Action?

Abstract Full Text
JAMA Oncol. 2024;10(7):885-886. doi:10.1001/jamaoncol.2024.0860

Community Health Care Workers Empowering Advance Care Planning

Abstract Full Text
JAMA Oncol. 2024;10(7):954-955. doi:10.1001/jamaoncol.2024.0375
Cancer Care Chronicles

Predictions

Abstract Full Text
JAMA Oncol. 2024;10(7):863. doi:10.1001/jamaoncol.2024.1140

This essay describes a physician鈥檚 experience with ushering a patient to the end of their life.

Poetry and Oncology

Snapshots From My Staycay With Chemo

Abstract Full Text
JAMA Oncol. 2024;10(7):991-992. doi:10.1001/jamaoncol.2024.1253
Comment & Response

Substance Use Disorders Among Cancer Survivors

Abstract Full Text
JAMA Oncol. 2024;10(7):986. doi:10.1001/jamaoncol.2024.1044

Umbilical Cord鈥揇erived Mesenchymal Stromal Cells For Prevention of Chronic Graft-vs-Host Disease

Abstract Full Text
JAMA Oncol. 2024;10(7):986-987. doi:10.1001/jamaoncol.2024.1521

Umbilical Cord鈥揇erived Mesenchymal Stromal Cells For Prevention of Chronic Graft-vs-Host Disease鈥擱eply

Abstract Full Text
JAMA Oncol. 2024;10(7):987-988. doi:10.1001/jamaoncol.2024.1524

Results of the TARGET-TP Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):988. doi:10.1001/jamaoncol.2024.0113

Results of the TARGET-TP Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2024;10(7):988-989. doi:10.1001/jamaoncol.2024.1869

Results of the TARGET-TP Randomized Clinical Trial鈥擱eply

Abstract Full Text
JAMA Oncol. 2024;10(7):989. doi:10.1001/jamaoncol.2024.0140
Correction

Errors in Figure 4 and Incorrect DNA Sequencing Manufacturer

Abstract Full Text
free access
JAMA Oncol. 2024;10(7):989. doi:10.1001/jamaoncol.2024.3204
JAMA Oncology Masthead

JAMA Oncology

Abstract Full Text
free access
JAMA Oncol. 2024;10(7):856. doi:10.1001/jamaoncol.2023.4652
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