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October 28, 2024
Viewpoint

Neonatal Neurocritical Care Training—The Time Has Come

Abstract Full Text
JAMA Neurol. Published online October 28, 2024. doi:10.1001/jamaneurol.2024.3619

This Viewpoint describes the advent of neonatal neurocritical care training, the data supporting the need and its efficacy, and the ways this training can optimize outcomes for vulnerable patients and their families.

On the Brain

A Clown With Traumatic Brain Injury

Abstract Full Text
JAMA Neurol. Published online October 28, 2024. doi:10.1001/jamaneurol.2024.3622

This essay describes the efforts patients might make to hold onto their humanity in the midst of an absurd world: being in the emergency department with a neurological injury.

Editorial

Mobile Stroke Units—Time for Legislation and Renumeration

Abstract Full Text
JAMA Neurol. Published online October 28, 2024. doi:10.1001/jamaneurol.2024.3627
Original Investigation

Mobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis

Abstract Full Text
JAMA Neurol. Published online October 28, 2024. doi:10.1001/jamaneurol.2024.3659

This cohort study investigates if prehospital management in a mobile stroke unit compared with standard emergency medical services management reduces the level of global disability at hospital discharge in patients with ischemic stroke who are potentially eligible for intravenous thrombolysis.

October 21, 2024
Viewpoint

Digital Biomarkers for Neurodegenerative Disease

Abstract Full Text
JAMA Neurol. Published online October 21, 2024. doi:10.1001/jamaneurol.2024.3533

This Viewpoint discusses using digital biomarkers for neurodegenerative disease.

Original Investigation

Development and Validation of a Clinical Score to Predict Epilepsy After Cerebral Venous Thrombosis

Abstract Full Text
JAMA Neurol. Published online October 21, 2024. doi:10.1001/jamaneurol.2024.3481

This study attempts to develop and externally validate a prognostic score to estimate the individual risk of postcerebral venous thrombosis epilepsy.

Risk of Inflammatory Central Nervous System Diseases After Tumor Necrosis Factor–Inhibitor Treatment for Autoimmune Diseases: A Systematic Review and Meta-Analysis

Abstract Full Text
JAMA Neurol. Published online October 21, 2024. doi:10.1001/jamaneurol.2024.3524

This systematic review and meta-analysis evaluates the risk of new-onset inflammatory central nervous system diseases after tumor necrosis factor–inhibitor treatment for autoimmune disease.

Hearing Loss, Incident Parkinson Disease, and Treatment With Hearing Aids

Abstract Full Text
JAMA Neurol. Published online October 21, 2024. doi:10.1001/jamaneurol.2024.3568

This cohort study analyzes electronic health record data for US veterans with an audiogram to determine whether hearing loss is associated with an increased risk of Parkinson disease and to gauge its effect modification by well-established prodromal conditions and hearing aids.

Research Letter

Genome Sequencing After Exome Sequencing in Pediatric Epilepsy

Abstract Full Text
JAMA Neurol. Published online October 21, 2024. doi:10.1001/jamaneurol.2024.3582

This cohort study examined the yield and use of genome sequencing after nondiagnostic exome sequencing for pediatric patients with unexplained epilepsy between August 2018 and May 2023.

October 14, 2024
Viewpoint

Collaborative Dementia Care During the New Therapeutic Era

Abstract Full Text
JAMA Neurol. Published online October 14, 2024. doi:10.1001/jamaneurol.2024.3379

This Viewpoint advocates for the implementation of collaborative care with care navigation in the diagnosis and treatment of Alzheimer disease.

Original Investigation

Multisite Skin Biopsies vs Cerebrospinal Fluid for Prion Seeding Activity in the Diagnosis of Prion Diseases

Abstract Full Text
JAMA Neurol. Published online October 14, 2024. doi:10.1001/jamaneurol.2024.3458

This diagnostic study evaluates the ability of multiple skin biopsies to detect prion seeding activity compared with the cerebrospinal fluid (CSF) as a diagnostic biomarker in prion diseases.

Images in Neurology

Crossed Clonus Response

Abstract Full Text
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JAMA Neurol. Published online October 14, 2024. doi:10.1001/jamaneurol.2024.3488

This case report describes a novel crossed clonus response in a 48-year-old man with compressive cervical myelopathy.

October 7, 2024
Viewpoint

Barriers to Tofersen Therapy for Variant SOD1-Mediated ALS

Abstract Full Text
JAMA Neurol. Published online October 7, 2024. doi:10.1001/jamaneurol.2024.3331

This Viewpoint advocates for the accelerated adoption of tofersen therapy to treat patients with variant SOD1-mediated amyotrophic lateral sclerosis (ALS) and describes the current barriers to treatment.

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