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October 2024 - July 1959

Decade

Year

Issue

October 2024, Vol 81, No. 10, Pages 1020-1103

Viewpoint

It Is Time for Medicare to Cover Driving Safety Assessments

Abstract Full Text
JAMA Neurol. 2024;81(10):1021-1022. doi:10.1001/jamaneurol.2024.2461

This Viewpoint advocates for Medicare coverage of driving assessments for older individuals.

Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases

Abstract Full Text
JAMA Neurol. 2024;81(10):1023-1024. doi:10.1001/jamaneurol.2024.2464

This Viewpoint describes the evidence for iatrogenic disease based on amyloid-β prions and the possibility that Alzheimer disease has an iatrogenic form wherein amyloid β and tau behave as prions that transmit the disease.

On the Brain

Behind the Brow That Furrows

Abstract Full Text
JAMA Neurol. 2024;81(10):1025-1026. doi:10.1001/jamaneurol.2024.2835

This essay describes the author’s observations while examining a pregnant mother who has multiple sclerosis.

Editorial

JAMA Neurology Editorial Fellowship—Call for Applicants

Abstract Full Text
JAMA Neurol. 2024;81(10):1027. doi:10.1001/jamaneurol.2024.2554

How Is the X Chromosome Involved in Alzheimer Disease?

Abstract Full Text
JAMA Neurol. 2024;81(10):1028-1029. doi:10.1001/jamaneurol.2024.2831

Blood-Based Biomarkers for Alzheimer Disease—Ready for Primary Care?

Abstract Full Text
JAMA Neurol. 2024;81(10):1030-1031. doi:10.1001/jamaneurol.2024.2801
Original Investigation

Role of the X Chromosome in Alzheimer Disease Genetics

Abstract Full Text
open access
JAMA Neurol. 2024;81(10):1032-1042. doi:10.1001/jamaneurol.2024.2843

This genetic association study evaluates the association between the X chromosome and Alzheimer disease.

Endovascular vs Medical Management of Acute Basilar Artery Occlusion: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2024;81(10):1043-1050. doi:10.1001/jamaneurol.2024.2652

This secondary analysis of a randomized clinical trial assesses 1-year clinical outcomes following endovascular thrombectomy in patients with acute basilar artery occlusion.

MRI Signature of α-Synuclein Pathology in Asymptomatic Stages and a Memory Clinic Population

Abstract Full Text
JAMA Neurol. 2024;81(10):1051-1059. doi:10.1001/jamaneurol.2024.2713

This cohort study investigates the association between cerebrospinal fluid seed amplification α-synuclein positivity and magnetic resonance imaging (MRI) structural measures across the continuum from clinically unimpaired to cognitively impaired individuals.

Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage: A Randomized Clinical Trial

Abstract Full Text
open access has audio
JAMA Neurol. 2024;81(10):1060-1065. doi:10.1001/jamaneurol.2024.2564

This randomized clinical trial investigated the safety and efficacy of nicardipine release implants for preventing proximal angiographic vasospasm after aneurysmal subarachnoid hemorrhage.

Lecanemab and Vascular-Amyloid Deposition in Brains of People With Down Syndrome

Abstract Full Text
JAMA Neurol. 2024;81(10):1066-1072. doi:10.1001/jamaneurol.2024.2579

This study investigates the binding properties of lecanemab in the brains of people with Down syndrome, in anticipation of their inclusion in clinical trials or access to antiamyloid immunotherapies.

Time to Treat First Acute Attack of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Abstract Full Text
JAMA Neurol. 2024;81(10):1073-1084. doi:10.1001/jamaneurol.2024.2811

This cohort study evaluates if the time to treat the first acute attack of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is associated with the disease course and seronegative conversion of anti–myelin oligodendrocyte glycoprotein immunoglobulin G.

Review

Endovascular Stroke Thrombectomy for Patients With Large Ischemic Core: A Review

Abstract Full Text
has active quiz
JAMA Neurol. 2024;81(10):1085-1093. doi:10.1001/jamaneurol.2024.2500

This narrative review discusses the results of 6 recently published trials on the efficacy and safety of endovascular thrombectomy as treatment for patients with ischemic stroke, anterior-circulation large vessel occlusions, and large areas of ischemic change and highlights areas of persistent uncertainty in the use of this treatment.

Images in Neurology

Steroid-Responsive Myorhythmia in Pectoralis Muscles

Abstract Full Text
has active quiz has multimedia
JAMA Neurol. 2024;81(10):1094-1095. doi:10.1001/jamaneurol.2024.2008

This case report describes a patient experiencing involuntary contractions in his right pectoralis muscles with anti-Tr antibodies in his serum, which is characteristic of myorhythmia.

Lesioning the Brain—From Serendipity to Science

Abstract Full Text
has active quiz has multimedia
JAMA Neurol. 2024;81(10):1096-1097. doi:10.1001/jamaneurol.2024.2221

This case report describes use of high-intensity focused ultrasound as a method to create spatially precise thermal lesions in the brain without a craniotomy.

Research Letter

Association of Cardiovascular Events With Spouse’s Subsequent Dementia

Abstract Full Text
JAMA Neurol. 2024;81(10):1098-1099. doi:10.1001/jamaneurol.2024.2612

This cohort study evaluates whether a spousal cardiovascular event is associated with one’s own risk of dementia.

Updated Multiple Sclerosis Incidence, 2015-2022

Abstract Full Text
JAMA Neurol. 2024;81(10):1100-1102. doi:10.1001/jamaneurol.2024.2876

This cohort study uses population-based claims data to provide an update of multiple sclerosis incidence in Germany.

Comment & Response

Sex Differences in Case-Fatality Rates of Stroke

Abstract Full Text
JAMA Neurol. 2024;81(10):1102-1103. doi:10.1001/jamaneurol.2024.2596

Sex Differences in Case-Fatality Rates of Stroke—Reply

Abstract Full Text
JAMA Neurol. 2024;81(10):1103. doi:10.1001/jamaneurol.2024.2599
Correction

Error in Figure

Abstract Full Text
free access
JAMA Neurol. 2024;81(10):1103. doi:10.1001/jamaneurol.2024.3566
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2024;81(10):1020. doi:10.1001/jamaneurol.2023.3787
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