July 1, 2022 Issue of JAMA Cardiology

July 2022, Vol 7, No. 7, Pages 662-776

Original Investigation

Association Between High-Density Lipoprotein Cholesterol Levels and Adverse Cardiovascular Outcomes in High-risk Populations

Chang Liu, MPH; Devinder Dhindsa, MD; Zakaria Almuwaqqat, MD, MPH; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):672-680. doi:10.1001/jamacardio.2022.0912

This cohort study investigates the association between very high high-density lipoprotein cholesterol (HDL-C) level and outcomes in patients with coronary artery disease.

Editor's Note
Very Elevated High-Density Lipoprotein Cholesterol and Mortality鈥擳he Good Gone Bad?
Sadiya S. Khan, MD, MSc; Gregg C. Fonarow, MD

JAMA Cardiol

Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke: A Post Hoc Analysis From the AUGUSTUS Trial

M. Cecilia Bahit, MD; Amit N. Vora, MD, MPH; Zhuokai Li, PhD; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):682-689. doi:10.1001/jamacardio.2022.1166

This randomized clinical trial analyzes data comparing treatment regimens according to prior stroke, transient ischemic attack, or thromboembolism to determine the safety and efficacy of apixaban, vitamin K antagonists, and aspirin.

Management of Acute Coronary Syndromes in Patients in Rural Australia: The MORACS Randomized Clinical Trial

Fiona Dee, RN; Lindsay Savage, RN; James W. Leitch, MBBS; et al.

Abstract Full Text

open access

JAMA Cardiol. 2022;7(7):690-698. doi:10.1001/jamacardio.2022.1188

This randomized clinical trial seeks to improve outcomes of ST-segment elevation myocardial infarction in rural areas in Australia by reducing missed diagnoses and increasing administration of primary reperfusion therapy.

Invited Commentary
Improving the Detection of ST-Segment Elevation Myocardial Infarction in Rural Settings: When Texting Saves Lives
Uchenna R. Ofoma, MD, MS; Karen E. Joynt Maddox, MD, MPH

JAMA Cardiol

Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial

Caroline Hauw-Berlemont, MD, MS; Lionel Lamhaut, MD, PhD; Jean-Luc Diehl, MD; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):700-707. doi:10.1001/jamacardio.2022.1416

This randomized clinical trial investigates the use of emergency coronary angiogram vs delayed coronary angiogram in patients who experience out-of-hospital cardiac arrest without ST-segment elevation.

Health Care Access and Management of Cardiovascular Risk Factors Among Working-Age Adults With Low Income by State Medicaid Expansion Status

Andrew S. Oseran, MD, MBA; Tianyu Sun, PhD; Rishi K. Wadhera, MD, MPP, MPhil

Abstract Full Text

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JAMA Cardiol. 2022;7(7):708-714. doi:10.1001/jamacardio.2022.1282

This cross-sectional study evaluates insurance coverage, health care access, and management of cardiovascular risk factors among working-age adults with low income by state Medicaid expansion status and individuals鈥� insurance status.

Rare and Common Genetic Variation Underlying the Risk of Hypertrophic Cardiomyopathy in a National Biobank

Kiran J. Biddinger; Sean J. Jurgens, BSc; Dimitri Maamari, MD; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):715-722. doi:10.1001/jamacardio.2022.1061

This cohort study examines data from the UK Biobank and Mass General Brigham Biobank to assess the contribution of rare and common genetic variants to risk of hypertrophic cardiomyopathy in the general population.

Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality

Aniruddh P. Patel, MD; Jacqueline S. Dron, PhD; Minxian Wang, PhD; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):723-732. doi:10.1001/jamacardio.2022.0901

This genetic association study investigates the association of pathogenic DNA variants implicated in inherited cardiomyopathy with cardiovascular disease outcomes and all-cause mortality.

Podcast: Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes

Editorial
Genetic Testing for Early-Onset Atrial Fibrillation鈥擨s It Time to Personalize Care?
Elizabeth M. McNally, MD, PhD; Sadiya S. Khan, MD, MS

JAMA Cardiol

Mortality Among Patients With Early-Onset Atrial Fibrillation and Rare Variants in Cardiomyopathy and Arrhythmia Genes

Zachary T. Yoneda, MD, MSCI; Katherine C. Anderson, ScM, CGC; Fei Ye, PhD; et al.

Abstract Full Text

open access has audio

JAMA Cardiol. 2022;7(7):733-741. doi:10.1001/jamacardio.2022.0810

This cohort study assesses the association of rare variants of cardiomyopathy and arrhythmia genes with all-cause mortality among patients with early-onset atrial fibrillation.

Podcast: Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes

Editorial
Genetic Testing for Early-Onset Atrial Fibrillation鈥擨s It Time to Personalize Care?
Elizabeth M. McNally, MD, PhD; Sadiya S. Khan, MD, MS

JAMA Cardiol

Brief Report

Trends in De Novo Hypertensive Disorders of Pregnancy Among Asian and Hispanic Population Subgroups in the United States, 2011 to 2019

Nilay S. Shah, MD, MPH; Katharine A. Harrington, MPH; Xiaoning Huang, PhD; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):742-746. doi:10.1001/jamacardio.2022.1378

This cross-sectional study examines data from the National Center for Health Statistics to determine rates of de novo hypertensive disorders of pregnancy among individuals with a first live birth according to racial and ethnic subgroup.

Research Letter

Trends in Transcatheter vs Surgical Mitral Valve Repair Among Medicare Beneficiaries, 2012 to 2019

Michael N. Young, MD; Stephen Kearing, MS; Mazen A. Albaghdadi, MD, MSc; et al.

Abstract Full Text

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JAMA Cardiol. 2022;7(7):770-772. doi:10.1001/jamacardio.2022.0775

This cross-sectional study of Medicare data from 2012 to 2019 assesses national trends in the use of mitral transcatheter edge-to-edge repair relative to surgical mitral valve repair.

Endurance Exercise Following Ascending Thoracic Aortic Aneurysm Resection in Bicuspid Aortic Valve Aortopathy

Andrew F. Lai, MD; Alan C. Braverman, MD

Abstract Full Text

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JAMA Cardiol. 2022;7(7):772-773. doi:10.1001/jamacardio.2022.1410

This case series study evaluates aortic outcomes in athletes performing endurance exercise or competition after ascending thoracic aortic aneurysm resection with bicuspid aortic valve aortopathy.

Viewpoint

Athletes With Cardiovascular Disease and Competitive Sports Eligibility: Progress and Challenges Ahead

Jonathan H. Kim, MD, MSc; Neal W. Dickert, MD, PhD

Abstract Full Text

JAMA Cardiol. 2022;7(7):663-664. doi:10.1001/jamacardio.2022.0806

This Viewpoint discusses patient centered shared-decision making for athletes with heart disease.

From the Heart

Passing the Stethoscope

Tim Sanborn, MD, MS

Abstract Full Text

JAMA Cardiol. 2022;7(7):665-666. doi:10.1001/jamacardio.2022.0656

This essay describes the author鈥檚 father, a surgeon, passing the baton on to him as a second-generation pysician.

Editorial

USPSTF Report on Aspirin for Primary Prevention

Donald M. Lloyd-Jones, MD, ScM

Abstract Full Text

JAMA Cardiol. 2022;7(7):667-669. doi:10.1001/jamacardio.2022.0935

This Editorial discusses recommendations from the US Preventive Services Task Force on aspirin use to prevent cardiovascular disease and colorectal cancer.

Editorial
Should Patients Take Aspirin for Primary Cardiovascular Prevention?Updated Recommendations From the US Preventive Services Task Force
Allan S. Brett, MD

JAMA
- Podcast: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease
Whom to Treat for Primary Prevention of Atherosclerotic Cardiovascular Disease: The Aspirin Dilemma
Samia Mora, MD, MHS; Chrisandra L. Shufelt, MD, MS; JoAnn E. Manson, MD, DrPH

JAMA Intern Med
- Podcast: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease

Genetic Testing for Early-Onset Atrial Fibrillation鈥擨s It Time to Personalize Care?

Elizabeth M. McNally, MD, PhD; Sadiya S. Khan, MD, MS

Abstract Full Text

JAMA Cardiol. 2022;7(7):669-671. doi:10.1001/jamacardio.2022.0909

Invited Commentary

Improving the Detection of ST-Segment Elevation Myocardial Infarction in Rural Settings: When Texting Saves Lives

Uchenna R. Ofoma, MD, MS; Karen E. Joynt Maddox, MD, MPH

Abstract Full Text

JAMA Cardiol. 2022;7(7):698-699. doi:10.1001/jamacardio.2022.1195

Review

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review

Behnood Bikdeli, MD, MS; Farbod Zahedi Tajrishi, MD; Parham Sadeghipour, MD; et al.

Abstract Full Text

has active quiz

JAMA Cardiol. 2022;7(7):747-759. doi:10.1001/jamacardio.2022.1292

This narrative review evaluates the alignment between clinical practice and randomized clinical trial findings in the use of dose-reduced direct oral anticoagulants.

Lipoprotein(a) and its Significance in Cardiovascular Disease: A Review

Freddy Duarte Lau, MD; Robert P. Giugliano, MD, SM

Abstract Full Text

has active quiz

JAMA Cardiol. 2022;7(7):760-769. doi:10.1001/jamacardio.2022.0987

This narrative review evaluates evidence of an association between elevated lipoprotein(a) levels, atherosclerotic cardiovascular disease, and aortic valve stenosis.

Cardiovascular Images

Incidental Murmur in a Preadolescent Boy

Jordan L. W. Lam, MBBS; Sara Saleh, MD; Cormac O. Maher, MD

Abstract Full Text

online only has active quiz has multimedia

JAMA Cardiol. 2022;7(7):e220927. doi:10.1001/jamacardio.2022.0927

This case report describes a preadolescent boy with a history of ventriculoperitoneal shunt and an incidental murmur found on physical examination.

Video: Ventriculoperitoneal Shunt Catheter Visualized by Transesophageal Echocardiography

Comment & Response

The 鈥淧ower of Zero鈥� in Younger Patients鈥擜 Glass Half Empty or a Glass Half Full?

Pedro M. Lopes, MD; Pedro Freitas, MD; António M. Ferreira, MD

Abstract Full Text

JAMA Cardiol. 2022;7(7):773-774. doi:10.1001/jamacardio.2022.0978

The 鈥淧ower of Zero鈥� in Younger Patients鈥擜 Glass Half Empty or a Glass Half Full?鈥擱eply

Martin Bødtker Mortensen, MD, PhD

Abstract Full Text

JAMA Cardiol. 2022;7(7):774. doi:10.1001/jamacardio.2022.0981

Macular Degeneration and CETP Inhibition

Alan R. Tall, MD; Daniel J. Rader, MD; John J. P. Kastelein, MD, PhD

Abstract Full Text

JAMA Cardiol. 2022;7(7):774-775. doi:10.1001/jamacardio.2022.1276

Macular Degeneration and CETP Inhibition鈥擱eply

Liv Tybjærg Nordestgaard, MD, PhD; Børge Grønne Nordestgaard, MD, DMSc; Anne Tybjærg-Hansen, MD, DMSc

Abstract Full Text

JAMA Cardiol. 2022;7(7):775-776. doi:10.1001/jamacardio.2022.1279

Editor's Note

Very Elevated High-Density Lipoprotein Cholesterol and Mortality鈥擳he Good Gone Bad?

Sadiya S. Khan, MD, MSc; Gregg C. Fonarow, MD

Abstract Full Text

JAMA Cardiol. 2022;7(7):681. doi:10.1001/jamacardio.2022.0924

Correction

Error in SI Conversion Factor

Abstract Full Text

free access

JAMA Cardiol. 2022;7(7):776. doi:10.1001/jamacardio.2022.2074

Error in Figure

Abstract Full Text

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JAMA Cardiol. 2022;7(7):776. doi:10.1001/jamacardio.2022.2240

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October 2024 - April 2016

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Issue

July 2022, Vol 7, No. 7, Pages 662-776

Association Between High-Density Lipoprotein Cholesterol Levels and Adverse Cardiovascular Outcomes in High-risk Populations

Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke: A Post Hoc Analysis From the AUGUSTUS Trial

Management of Acute Coronary Syndromes in Patients in Rural Australia: The MORACS Randomized Clinical Trial

Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial

Health Care Access and Management of Cardiovascular Risk Factors Among Working-Age Adults With Low Income by State Medicaid Expansion Status

Rare and Common Genetic Variation Underlying the Risk of Hypertrophic Cardiomyopathy in a National Biobank

Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality

Mortality Among Patients With Early-Onset Atrial Fibrillation and Rare Variants in Cardiomyopathy and Arrhythmia Genes

Trends in De Novo Hypertensive Disorders of Pregnancy Among Asian and Hispanic Population Subgroups in the United States, 2011 to 2019

Trends in Transcatheter vs Surgical Mitral Valve Repair Among Medicare Beneficiaries, 2012 to 2019

Endurance Exercise Following Ascending Thoracic Aortic Aneurysm Resection in Bicuspid Aortic Valve Aortopathy

Athletes With Cardiovascular Disease and Competitive Sports Eligibility: Progress and Challenges Ahead

Passing the Stethoscope

USPSTF Report on Aspirin for Primary Prevention

Genetic Testing for Early-Onset Atrial Fibrillation鈥擨s It Time to Personalize Care?

Improving the Detection of ST-Segment Elevation Myocardial Infarction in Rural Settings: When Texting Saves Lives

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review

Lipoprotein(a) and its Significance in Cardiovascular Disease: A Review

Incidental Murmur in a Preadolescent Boy

The 鈥淧ower of Zero鈥� in Younger Patients鈥擜 Glass Half Empty or a Glass Half Full?

The 鈥淧ower of Zero鈥� in Younger Patients鈥擜 Glass Half Empty or a Glass Half Full?鈥擱eply

Macular Degeneration and CETP Inhibition

Macular Degeneration and CETP Inhibition鈥擱eply

Very Elevated High-Density Lipoprotein Cholesterol and Mortality鈥擳he Good Gone Bad?

Error in SI Conversion Factor

Error in Figure

JAMA Cardiology

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