ÌÇÐÄvlog

This randomized withdrawal study compares the efficacy of esketamine nasal spray plus an oral antidepressant with an oral antidepressant plus placebo nasal spray in delaying relapse of depressive symptoms in patients with treatment-resistant depression who were in stable remission after treatment with esketamine nasal spray plus an oral antidepressant.

This network meta-analysis compared 12 randomized clinical trials comprising 992 patients to assess the short- and long-term outcomes of psychotherapy, pharmacotherapy, and combination therapies for adults with posttraumatic stress disorder.

This systematic review and meta-analysis examines articles indexed in Web of Science and PubMed to understand the advantages of identifying blood and cerebrospinal fluid markers in the endocannabinoid system in the diagnosis and prognosis of psychotic disorder.

This report of a genome-wide association study and a mouse-model study assesses genetic variants associated with anxiety and stress-related disorders among participants in the Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) study and mice exposed to social defeat.

This study analyzes nearly 20 years of suicide data from the Centers for Disease Control and Prevention, as well as specific Twitter and Instagram posts, to estimate incidence of suicide among children and teenagers exposed to the suicide theme and depiction in the Netflix show 13 Reasons Why.

This pharmacoepidemiologic study explores the possible association between parental use of prescription opioids and the increasing rate of youth suicide.

This nested case-control study examines the association of maternal benzodiazepine use by pregnant women and by drug class, duration of action, and specific benzodiazepine agent with the risk of spontaneous abortion in Canadian women during early pregnancy.

This cohort study uses neuroimaging to examine which neural reward regions are associated with improved psychiatric symptoms and psychosocial function in young adults.

This community-based cohort study compares the association of low socioeconomic status and traumatic stressful events with psychopathology, puberty, neurocognition, and multimodal neuroimaging parameters in brain maturation among children and young adults.