Marc M. Bohlken, MSc; Rachel M. Brouwer, PhD; René C. W. Mandl, PhD; et al.
free access
JAMA Psychiatry. 2016;73(1):11-19. doi:10.1001/jamapsychiatry.2015.1925
This twin study uses structural equation modeling to examine whether white matter integrity is associated with the genetic liability for developing schizophrenia.
Debra D’Angelo, MS; Sébastien Lebon, MD; Qixuan Chen, PhD; et al.
free access
JAMA Psychiatry. 2016;73(1):20-30. doi:10.1001/jamapsychiatry.2015.2123
This international cohort study assesses the effects of the 16p11.2 duplication on cognitive, behavioral, medical, and anthropometric traits in carriers and compared these findings with effects in 16p11.2 deletion carriers and the relatives of both groups.
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Editorial
Following the Trail From Genotype to Phenotypes
Catherine Lord, PhD; Jeremy Veenstra-VanderWeele, MD
JAMA Psychiatry
Joan L. Luby, MD; Andy C. Belden, PhD; Joshua J. Jackson, PhD; et al.
free access
JAMA Psychiatry. 2016;73(1):31-38. doi:10.1001/jamapsychiatry.2015.2356
This longitudinal behavioral and neuroimaging study reports an association between childhood depression and the trajectory of cortical gray matter development in late school-aged children and those in early adolescence.
Bridget F. Grant, PhD, PhD; Tulshi D. Saha, PhD; W. June Ruan, MA; et al.
free access
JAMA Psychiatry. 2016;73(1):39-47. doi:10.1001/jamapsychiatry.2015.2132
This survey study presents nationally representative findings on the prevalence, correlates, psychiatric comorbidity, disability, and treatment of DSM-5 drug use disorder diagnoses overall and by severity level.
Eva Velthorst, PhD; Abraham Reichenberg, PhD; Ori Kapra, BA; et al.
free access
JAMA Psychiatry. 2016;73(1):48-55. doi:10.1001/jamapsychiatry.2015.2253
This population-based study of Israeli male adolescents who underwent behavioral assessment to determine military service eligibility reports that different components of impaired community functioning in schizophrenia followed different developmental trajectories.
Raymond W. Lam, MD; Anthony J. Levitt, MBBS; Robert D. Levitan, MD, MSc; et al.
free access
JAMA Psychiatry. 2016;73(1):56-63. doi:10.1001/jamapsychiatry.2015.2235
This randomized clinical trial compares the efficacy of light treatment, both as monotherapy and in combination with fluoxetine, with a sham placebo condition for adults with nonseasonal major depressive disorder.
Meta-analysis
Jack C. Rogers, PhD; Stéphane A. De Brito, PhD
free access
JAMA Psychiatry. 2016;73(1):64-72. doi:10.1001/jamapsychiatry.2015.2423
This meta-analysis of whole-brain structural neuroimaging studies of youths with conduct problems identifies gray matter reductions within the insula, amygdala, and frontal and temporal regions.
Tina D. Hoang, MSPH; Jared Reis, PhD; Na Zhu, MD, MPH; et al.
free access
JAMA Psychiatry. 2016;73(1):73-79. doi:10.1001/jamapsychiatry.2015.2468
This observational study evaluates the effect of physical activity levels and television viewing habits of young adults over a 25-year period on cognitive function at midlife.
Dale C. Hesdorffer, PhD; Lianna Ishihara, PhD; David J. Webb, MSc; et al.
free access
JAMA Psychiatry. 2016;73(1):80-86. doi:10.1001/jamapsychiatry.2015.2516
This cohort study reports on the magnitude of the association between attempted suicide and epilepsy.