ÌÇÐÄvlog

This randomized clinical trial investigates if intrapleural tissue plasminogen activator and dornase alfa is more effective than intrapleural tissue plasminogen activator alone at reducing hospital length of stay in children with pleural empyema.

This systematic review and network meta-analysis examines whether prophylactic pharmacologic treatments are more effective than placebo and whether there are differences between drugs regarding efficacy, safety, and acceptability.

This cohort study characterizes US trends in primary care visit rates among individuals 17 or younger covered by a large national commercial health plan from 2008 to 2016 and identifies variables associated with visit rates.

This population-based cross-sectional study assesses whether antenatal transfer of pregnant women to a level III hospital in a perinatal network is associated with reduced neonatal mortality in infants born very preterm.

This diagnostic accuracy study compares the sensitivity and specificity of 3 screening tools—the Ages and Stages Questionnaire, Parents’ Evaluation of Developmental Status, and Survey of Well-being of Young Children: Milestones—used for detecting developmental delays among infants and young children.

This systematic review and meta-analysis evaluates published data on pubertal timing based on age at thelarche and evaluates the change in pubertal onset in healthy girls around the world.

This systematic review and meta-analysis compares sustained inflation vs intermittent positive pressure ventilation and continuous positive airway pressure for the prevention of hospital mortality and morbidity for preterm infants.