Simiao Chen, ScD; Zhong Cao, BE; Klaus Prettner, PhD; et al.
open access
JAMA Oncol. 2023;9(4):465-472. doi:10.1001/jamaoncol.2022.7826
This decision analytical model study estimates the macroeconomic cost of 29 cancers in 204 countries and territories.
Erik Eckhert, MD, MS; Olivia Lansinger, BA; Victor Ritter, PhD; et al.
free access
JAMA Oncol. 2023;9(4):473-480. doi:10.1001/jamaoncol.2022.7146
This case-control study investigates the quality of breast cancer treatment and recurrence outcomes for patients from sex and gender minority groups compared with cisgender heterosexual patients.
Yvonne M. Geurts, MSc; Rebecca Shakir, MD, DPhil; Georgios Ntentas, DPhil; et al.
open access
JAMA Oncol. 2023;9(4):481-489. doi:10.1001/jamaoncol.2022.7153
This nested case-control study of 5-year Hodgkin lymphoma survivors explores dose-response associations of radiation therapy and procarbazine with colorectal cancer.
Aranzazu Fernandez-Martinez, MD, PhD; Tomás Pascual, MD; Baljit Singh, MD; et al.
open access
JAMA Oncol. 2023;9(4):490-499. doi:10.1001/jamaoncol.2022.6288
This prognostic study (in which a combined correlative analysis of the CALGB 40601 and PAMELA trials was conducted) compares the effectiveness of tumor-infiltrating lymphocytes vs immune-related gene expression signatures in predicting pathologic complete response and event-free survival in patients with early-stage ERBB2/HER2-positive breast cancer.
Daniel S. Peiffer, MD, PhD; Fangyuan Zhao, MA; Nan Chen, MD; et al.
open access
JAMA Oncol. 2023;9(4):500-510. doi:10.1001/jamaoncol.2022.7476
This cohort study uses National Cancer Database data to investigate whether breast cancer with low ERBB2 expression is a clinically distinct subtype compared with breast cancer with no ERBB2 expression, with distinct epidemiological characteristics, prognosis, and response to neoadjuvant chemotherapy.
Neil F. Mariados, MD; Peter F. Orio III, DO, MS; Zvi Schiffman, MD; et al.
open access
JAMA Oncol. 2023;9(4):511-518. doi:10.1001/jamaoncol.2022.7592
This randomized clinical trial examines whether a hyaluronic acid rectal spacer could improve rectal dosimetry and affect acute grade 2 or higher gastrointestinal toxic effects for hypofractionated radiation therapy.
Martin Bornhäuser, MD; Christoph Schliemann, MD; Johannes Schetelig, MD; et al.
free access
JAMA Oncol. 2023;9(4):519-526. doi:10.1001/jamaoncol.2022.7605
This randomized clinical trial of adults with intermediate-risk acute myeloid leukemia explores the optimal therapy for these patients after complete remission.
Mark A. Socinski, MD; Robert M. Jotte, MD, PhD; Federico Cappuzzo, MD; et al.
open access
JAMA Oncol. 2023;9(4):527-535. doi:10.1001/jamaoncol.2022.7711
This analysis of pooled data from 3 randomized clinical trials evaluates the association between immune-related adverse events and atezolizumab efficacy in patients with advanced non–small cell lung cancer.
Kent F. Hoskins, MD; Gregory S. Calip, PharmD, MPH, PhD; Hsiao-Ching Huang, MPH; et al.
free access
JAMA Oncol. 2023;9(4):536-545. doi:10.1001/jamaoncol.2022.7705
This retrospective mediation analysis examines the proportion of the Black-White disparity in breast cancer survival from estrogen receptor–positive, axillary node-negative breast cancer that is mediated by adverse social determinants and high-risk tumor biology.