ÌÇÐÄvlog

This case-control study evaluates pathogenic variants in panel genes tested in women with breast cancer.

This study examines the association among mismatch repair deficiency, microsatellite instability, and survival in patients with resectable gastroesophageal cancer randomized to surgery alone or perioperative chemotherapy.

This longitudinal registry study assesses the clinical spectra and age-related penetrance in individuals with pheochromocytomas and paragangliomas and mutations in the SDHA, TMEM127, MAX, and SDHAF2 genes.

This survey evaluates pediatric patients’ and parents’ perceptions of symptom burden during early cancer treatment and assesses their attitudes toward early integration of palliative care in pediatric oncology.

This randomized clinical trial compares the effects of metronomic chemotherapy on progression-free survival vs placebo in pediatric patients with primary extracranial, nonhematopoietic solid malignant tumors that progress after at least 2 lines of chemotherapy.

This population-based, case-control, cohort study uses data from the Breast Cancer Surveillance Consortium to assess risk factors associated with breast cancer in premenopausal and postmenopausal women.

This phase 2 trial assesses the effect of neoadjuvant chemotherapy followed by surgery on survival in patients with metastatic gastric and gastroesophageal junction cancer.

This study analyzes how patient preferences and burden of disease can be incorporated into randomized clinical trials in oncology using Bayesian decision analysis and the impact that these factors have on statistical thresholds for drug approval.

This phase 1/2 open-label study reports a planned update of the safety and efficacy of durvalumab in patients with locally advanced/metastatic urothelial carcinoma who had progressed on, were ineligible for, or refused prior chemotherapy.