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October 2024 - April 2015

Decade

Year

Issue

June 2017, Vol 3, No. 6, Pages 719-860

Original Investigation

Out-of-Pocket Spending and Financial Burden Among Medicare Beneficiaries With Cancer

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):757-765. doi:10.1001/jamaoncol.2016.4865

This study uses data from the Heath and Retirement Study to measure out-of-pocket costs incurred by Medicare beneficiaries with cancer and identify which factors contribute to high out-of-pocket costs.

Association of Proton Pump Inhibitors and Capecitabine Efficacy in Advanced Gastroesophageal Cancer: Secondary Analysis of the TRIO-013/LOGiC Randomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):767-773. doi:10.1001/jamaoncol.2016.3358

This secondary analysis of the TRIO-013 phase 3 randomized clinical trial attempts to determine if gastric acid suppressants such as proton pump inhibitors may impair capecitabine efficacy.

Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma

Abstract Full Text
open access
JAMA Oncol. 2017;3(6):774-783. doi:10.1001/jamaoncol.2016.3916

This cohort study uses resected cases from the International Cancer Genome Consortium to classify pancreatic ductal adenocarcinoma according to distinct mutational processes.

Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):784-792. doi:10.1001/jamaoncol.2016.6020

This secondary analysis of a randomized clinical trial assesses whether molecular variables improve prognostic classification of glioblastomas treated with radiation and temozolomide.

Adjuvant Capecitabine in Combination With Docetaxel, Epirubicin, and Cyclophosphamide for Early Breast Cancer: The Randomized Clinical FinXX Trial

Abstract Full Text
open access
JAMA Oncol. 2017;3(6):793-800. doi:10.1001/jamaoncol.2016.6120

This randomized clinical trial compares 10-year survival rates for 2 adjuvant combination therapies for early breast cancer: docetaxel followed by cyclophosphamide, epirubicin, and fluorouracil vs docetaxel plus capecitabine followed cyclophosphamide, epirubicin, and capecitabine.

Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):801-809. doi:10.1001/jamaoncol.2016.6108

This genomic analysis compares the prevalence and types of mutations in a cohort of black and white patients with lung cancer.

Prevalence of Genital Human Papillomavirus Infection and Human Papillomavirus Vaccination Rates Among US Adult Men: National Health and Nutrition Examination Survey (NHANES) 2013-2014

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):810-816. doi:10.1001/jamaoncol.2016.6192

This cross-sectional study of the NHANES 2013-2014 estimates the prevalence of genital human papillomavirus (HPV) infection and the HPV vaccination rate in the United States among adult men and examines potential risk factors for HPV infection.

Resource Use and Medicare Costs During Lay Navigation for Geriatric Patients With Cancer

Abstract Full Text
open access
JAMA Oncol. 2017;3(6):817-825. doi:10.1001/jamaoncol.2016.6307

This study examines the influence of lay navigation on health care spending and resource use among geriatric patients with cancer within an academic health system cancer community network.

Brief Report

Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA)

Abstract Full Text
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JAMA Oncol. 2017;3(6):827-831. doi:10.1001/jamaoncol.2016.3834

This database analysis evaluates the addition of gene mutations and alterations to the criteria of the Diagnosis-Specific Graded Prognostic Assessment and updates its prognostic capacity in non–small-cell lung cancer with newly diagnosed brain metastases.

Population-Based Incidence Rates of Cervical Intraepithelial Neoplasia in the Human Papillomavirus Vaccine Era

Abstract Full Text
open access
JAMA Oncol. 2017;3(6):833-837. doi:10.1001/jamaoncol.2016.3609

This population-based registry study determines the cervical intraepithelial neoplasia trends among female adolescents and young women after adjusting for changes in cervical screening practices that overlapped with HPV vaccination implementation.

Research Letter

Independent Validation of Effect of HSD3B1 Genotype on Response to Androgen-Deprivation Therapy in Prostate Cancer

Abstract Full Text
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JAMA Oncol. 2017;3(6):856-857. doi:10.1001/jamaoncol.2017.0147

Using data from a prostate cancer registry, this study correlated HSD3B1 genotype with response to androgen-deprivation therapy in patients with prostate cancer.

Review

Oncolytic Viruses in Cancer Treatment: A Review

Abstract Full Text
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JAMA Oncol. 2017;3(6):841-849. doi:10.1001/jamaoncol.2016.2064

This review discusses oncolytic viruses that are currently in preclinical and clinical trials for treatment of many types of cancer.

JAMA Oncology Clinical Challenge

Rapidly Enlarging Thyroid Mass in a Patient With History of Multiple Cancers

Abstract Full Text
JAMA Oncol. 2017;3(6):853-854. doi:10.1001/jamaoncol.2016.7084

A woman in her 30s presented with a palpable, nontender, firm mass in the neck. She had a medical history of high-grade osteosarcoma with areas of leimyosarcoma of the tibia. What is your diagnosis?

Viewpoint

A Case Where Switching the End Points for Clinical Trial Interpretation Might Be the Right Choice

Abstract Full Text
JAMA Oncol. 2017;3(6):735-736. doi:10.1001/jamaoncol.2016.4896

This Viewpoint examines the value of changing end points in a phase 3 clinical trials.

Drug-Drug Interactions With Oral Antineoplastic Agents

Abstract Full Text
JAMA Oncol. 2017;3(6):736-738. doi:10.1001/jamaoncol.2016.3323

This Viewpoint addresses the increasing incidence of drug-drug interactions with personalized cancer treatment drugs.

Trustworthiness of Patient-Reported Outcomes in Unblinded Cancer Clinical Trials

Abstract Full Text
JAMA Oncol. 2017;3(6):738-739. doi:10.1001/jamaoncol.2016.3328

This Viewpoint discusses the trustworthiness of patient-reported outcomes in unblinded cancer clinical trials.

Technology Spotlight

Genomic Analysis of Plasma Cell-Free DNA in Patients With Cancer

Abstract Full Text
JAMA Oncol. 2017;3(6):740-741. doi:10.1001/jamaoncol.2016.2835

This Viewpoint examines the use of assays that allow for genetic analyses of plasma cell-free DNA in patients with cancer.

From the ÌÇÐÄvlog

Chemoradiation for Locally Advanced Unresectable Pancreatic Cancer—What Now?

Abstract Full Text
JAMA Oncol. 2017;3(6):850-851. doi:10.1001/jamaoncol.2016.3012

This commentary discusses lessons learned from a trial published in JAMA that reported no difference in survival between chemoradiotherapy vs chemotherapy alone in patients with locally advanced unresectable pancreatic cancer.

Invited Commentary

Mitigating Financial Toxicity Among US Patients With Cancer

Abstract Full Text
JAMA Oncol. 2017;3(6):765-766. doi:10.1001/jamaoncol.2016.4850

Patient Navigation—An Effective Strategy to Reduce Health Care Costs and Improve Health Outcomes

Abstract Full Text
JAMA Oncol. 2017;3(6):825-826. doi:10.1001/jamaoncol.2016.6107

Association of Molecular Marker Status With Graded Prognostic Assessment of Lung Cancer With Brain Metastases

Abstract Full Text
JAMA Oncol. 2017;3(6):831-832. doi:10.1001/jamaoncol.2016.3818
Cancer Care Chronicles

The Patient I Thought I Knew

Abstract Full Text
JAMA Oncol. 2017;3(6):742-743. doi:10.1001/jamaoncol.2016.3331
Comment & Response

Risk of Bias and Heterogeneity

Abstract Full Text
JAMA Oncol. 2017;3(6):857-858. doi:10.1001/jamaoncol.2017.0164

Risk of Bias and Heterogeneity—Reply

Abstract Full Text
JAMA Oncol. 2017;3(6):858-859. doi:10.1001/jamaoncol.2017.0160

Inferior Survival Rates After Chemoradiation for Rectal Cancer Without Surgery

Abstract Full Text
JAMA Oncol. 2017;3(6):859. doi:10.1001/jamaoncol.2016.6618

Inferior Survival Rates After Chemoradiation for Rectal Cancer Without Surgery—Reply

Abstract Full Text
JAMA Oncol. 2017;3(6):859-860. doi:10.1001/jamaoncol.2017.0407
Correction

Errors in Table

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):860. doi:10.1001/jamaoncol.2016.5910
JAMA Oncology Masthead

JAMA Oncology

Abstract Full Text
free access
JAMA Oncol. 2017;3(6):721. doi:10.1001/jamaoncol.2016.4440
In This Issue of JAMA Oncology

Highlights

Abstract Full Text
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JAMA Oncol. 2017;3(6):719. doi:10.1001/jamaoncol.2016.4439
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