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JAMA Dermatology
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October 2024 - January 1920

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March 2023, Vol 159, No. 3, Pages 244-348

Viewpoint

Double Standards and Inconsistencies in Access to Care鈥擶hat Constitutes a Cosmetic Treatment?

John S. Barbieri, MD, MBA; Avery LaChance, MD, MPH; Joerg Albrecht, MD, PhD
Abstract Full Text
has audio
JAMA Dermatol. 2023;159(3):245-246. doi:10.1001/jamadermatol.2022.6322

This Viewpoint examines the inconsistencies in classification of cosmetic vs medical care and offers potential solutions to the issue of payers not providing coverage for skin conditions that have psychosocial effects.

  • Podcast: Double Standards and Inconsistencies in Access to Dermatologic Care
Editorial

Therapeutic Relief for Erythrodermic Atopic Dermatitis

Dawn Z. Eichenfield, MD, PhD
Abstract Full Text
JAMA Dermatol. 2023;159(3):247-248. doi:10.1001/jamadermatol.2022.6162

Differentiating Activity From Damage鈥擳he Morphological Challenge of Morphea

Amanda M. Saracino, MBBS, BMedSci, PhD; Mandana Nikpour, MBBS, PhD
Abstract Full Text
JAMA Dermatol. 2023;159(3):249-251. doi:10.1001/jamadermatol.2022.6364
Original Investigation

Efficacy and Safety of Dupilumab in Patients With Erythrodermic Atopic Dermatitis: A Post Hoc Analysis of 6 Randomized Clinical Trials

Amy S. Paller, MD; Jonathan I. Silverberg, MD, PhD; Michael J. Cork, PhD; et al.
Abstract Full Text
open access
JAMA Dermatol. 2023;159(3):255-266. doi:10.1001/jamadermatol.2022.6192

This post hoc analysis of 6 randomized, double-blind, placebo-controlled trials assesses the efficacy and safety of dupilumab in patients with erythrodermic atopic dermatitis.

Trends in the Prevalence of Methylchloroisothiazolinone/Methylisothiazolinone Contact Allergy in North America and Europe

Margo J. Reeder, MD; Erin Warshaw, MD, MS; Srikanth Aravamuthan, MS; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):267-274. doi:10.1001/jamadermatol.2022.5991

This cohort study examines the prevalence of positive patch test reactions to methylchloroisothiazolinone/methylisothiazolinone combination and methylisothiazolinone alone in North America and Europe.

Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study

Sizheng Steven Zhao, MD, PhD; Zenas Z. N. Yiu, MD, PhD; Anne Barton, MD, PhD; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):275-280. doi:10.1001/jamadermatol.2022.6051

This mendelian randomization examines the association between genetically proxied lipid-lowering drugs and psoriasis risk.

Prevalence and Odds of Depressive and Anxiety Disorders and Symptoms in Children and Adults With Alopecia Areata: A Systematic Review and Meta-analysis

Sophie Lauron, MD; Camille Plasse, MD; Marion Vaysset, MD; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):281-288. doi:10.1001/jamadermatol.2022.6085

This systematic review and meta-analysis performs separate analyses of the prevalence of depressive and anxiety disorders and the prevalence of depressive and anxiety symptoms in patients with alopecia areata.

Risk of Infection in Children With Psoriasis Receiving Treatment With Ustekinumab, Etanercept, or Methotrexate Before and After Labeling Expansion

Maria C. Schneeweiss, MD; Timothy J. Savage, MD, MPH; Richard Wyss, PhD; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):289-298. doi:10.1001/jamadermatol.2022.6325

This cohort study uses insurance claims data to estimate the 6-month rate of infections among children with psoriasis who started treatment with ustekinumab, etanercept, or methotrexate.

Development and Validation of the Morphea Activity Measure in Patients With Pediatric Morphea

Maria Teresa García-Romero, MD, MPH; Megha Tollefson, MD; Elena Pope, MD, MSc; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):299-307. doi:10.1001/jamadermatol.2022.6365

This diagnostic study uses a Delphi consensus method to develop the Morphea Activity Measure, a scoring tool designed to evaluate morphea disease activity of any type and severity for use in clinical and research settings, and validates the tool among pediatric patients with morphea.

Brief Report

Clinical Associations of Degos-Like Lesions in Patients With Systemic Sclerosis

Paula Song, MD; Shufeng Li, MS; Matthew A. Lewis, MD; et al.
Abstract Full Text
JAMA Dermatol. 2023;159(3):308-313. doi:10.1001/jamadermatol.2022.6330

This cohort study assesses the cutaneous and systemic manifestations of systemic sclerosis.

Review

Values and Preferences of Patients and Caregivers Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review

Keon Andre Maleki-Yazdi, MD, MSc; Anja Fog Heen, MD; Irene X. Zhao, BHSc; et al.
Abstract Full Text
has active quiz
JAMA Dermatol. 2023;159(3):320-330. doi:10.1001/jamadermatol.2022.6045

This systematic review summarizes the values and preferences of patients and caregivers regarding the treatment of atopic dermatitis (eczema).

Images in Dermatology

Benign Familial Pemphigus in Skin of Color

Jamie B. Harris, BS; Tyler Werbel, MD, MS; Sami K. Saikaly, MD
Abstract Full Text
has active quiz
JAMA Dermatol. 2023;159(3):331. doi:10.1001/jamadermatol.2022.5117

This case report describes friable erythematous plaques on the neck, inguinal folds, buttocks, bilateral axillae, and bilateral antecubital fossae.

Cutaneous Angiosarcoma

Jason C. Klein, MD, PhD; Arturo R. Dominguez, MD
Abstract Full Text
has active quiz
JAMA Dermatol. 2023;159(3):332. doi:10.1001/jamadermatol.2022.5446

This case report describes a large, purpuric plaque involving most of the right face with associated periorbital swelling but without ulceration.

JAMA Dermatology Clinicopathological Challenge

Pruritic Rash in a Woman With Endometrial Cancer

Sydney E. Liang, MD; Randie H. Kim, MD, PhD
Abstract Full Text
has active quiz
JAMA Dermatol. 2023;159(3):333-334. doi:10.1001/jamadermatol.2022.6349

A woman in her 60s presents with a pruritic rash that initially developed on the legs and progressed to her feet, arms, hands, and trunk, with associated symptoms of a burning sensation and occasional pain. What is your diagnosis?

Persistent Green-Blue Plaque in a Healthy Woman

Brenna G. Kelly, BA; Ting Liu, MD; Dekker C. Deacon, MD, PhD
Abstract Full Text
has active quiz
JAMA Dermatol. 2023;159(3):335-336. doi:10.1001/jamadermatol.2022.6356

A woman in her 30s presents with a bruise on her hand with a blue-green plaque that appeared after a twisting injury to the affected hand. What is your diagnosis?

JAMA Dermatology Patient Page

Drug Reaction With Eosinophilia and Systemic Symptoms

Matthew S. Krantz, MD; Elizabeth J. Phillips, MD
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):348. doi:10.1001/jamadermatol.2022.4519

This Patient Page describes the symptoms, diagnosis, and treatment of drug reaction with eosinophilia and systemic symptoms.

Research Letter

Assessing the Discriminatory Ability of Diagnostic Criteria for Ulcerative Pyoderma Gangrenosum and Its Mimickers

Antonio Ji-Xu, BM BCh; William Liakos, MD; Alexander Merleev, PhD; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):337-338. doi:10.1001/jamadermatol.2022.5978

This comparative effectiveness research study assesses the discriminatory ability of diagnostic criteria for pyoderma gangrenosum.

Outcomes Associated With Neutropenia and Lymphopenia in Epidermal Necrolysis: A Single-Center Retrospective Study of 147 Patients

Saskia Ingen-Housz-Oro, MD; Thomas Bettuzzi, MD; Bouchra Badaoui, MD; et al.
Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):338-340. doi:10.1001/jamadermatol.2022.6262

This retrospective cohort study examines the association of lymphocyte and neutrophil levels with treatment outcomes in 147 patients with epidermal necrolysis in France.

Observation

Treatment of Trichilemmomas With Topical Sirolimus

Anisha Bhanot, MD; Katelin Harrell, MD; Jarad Levin, MD
Abstract Full Text
JAMA Dermatol. 2023;159(3):340-342. doi:10.1001/jamadermatol.2022.5701

This case report describes a woman in her 60s flesh-colored papules that were localized to the central face and a lobular downgrowth of cells with clear, expanded, faintly glassy cytoplasm.

Treatment of Recurrent Epidermolysis Bullosa Acquisita With Tofacitinib

Birao Fan, MD; Mingyue Wang, MD, PhD
Abstract Full Text
JAMA Dermatol. 2023;159(3):342-344. doi:10.1001/jamadermatol.2022.6250

This case report describes a patient with recurrent epidermolysis bullosa acquisita who was treated with tofacitinib.

Correction

Error in Figure 1

Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):344. doi:10.1001/jamadermatol.2023.0470
JAMA Dermatology Masthead

JAMA Dermatology

Abstract Full Text
free access
JAMA Dermatol. 2023;159(3):244. doi:10.1001/jamadermatol.2022.4404
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